S. Kimura, et.al., The T/ebp null mouse: thyroid-specific enhancer-binding protein is essential for the organogenesis of the thyroid, lung, ventral forebrain, and pituitary., Genes & development, 1996, 10

http://rdf.ncbi.nlm.nih.gov/pubmed/8557195

S. Kimura, et.al., The T/ebp null mouse: thyroid-specific enhancer-binding protein is essential for the organogenesis of the thyroid, lung, ventral forebrain, and pituitary., Genes & development, 1996, 10

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Nkx2-1<tm1Shk>
  http://metadb.riken.jp/db/mgi_rdf/MGI:1857494

class

http://purl.org/net/cito/citesAsAuthority

• Nkx2-1<tm1Shk>
  http://metadb.riken.jp/db/mgi_rdf/MGI:1857494

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal pleural cavity morphology_Nkx2-1<tm1Shk>/Nkx2-1<tm1Shk>
  http://metadb.riken.jp/0012684I129S4SvJaeNkx21tm1ShkNkx21tm1ShkNkx21tm1Shk
• neonatal lethality, complete penetrance_Nkx2-1<tm1Shk>/Nkx2-1<tm1Shk>
  http://metadb.riken.jp/0011087I129S4SvJaeNkx21tm1ShkNkx21tm1ShkNkx21tm1Shk
• abnormal hypothalamus morphology_Nkx2-1<tm1Shk>/Nkx2-1<tm1Shk>
  http://metadb.riken.jp/0000837I129S4SvJaeNkx21tm1ShkNkx21tm1ShkNkx21tm1Shk
• abnormal lung development_Nkx2-1<tm1Shk>/Nkx2-1<tm1Shk>
  http://metadb.riken.jp/0001176I129S4SvJaeNkx21tm1ShkNkx21tm1ShkNkx21tm1Shk
• abnormal bronchus epithelium morphology_Nkx2-1<tm1Shk>/Nkx2-1<tm1Shk>
  http://metadb.riken.jp/0010943I129S4SvJaeNkx21tm1ShkNkx21tm1ShkNkx21tm1Shk
• abnormal pulmonary alveolar parenchyma morphology_Nkx2-1<tm1Shk>/Nkx2-1<tm1Shk>
  http://metadb.riken.jp/0010901I129S4SvJaeNkx21tm1ShkNkx21tm1ShkNkx21tm1Shk
• decreased fetal weight_Nkx2-1<tm1Shk>/Nkx2-1<tm1Shk>
  http://metadb.riken.jp/0009431I129S4SvJaeNkx21tm1ShkNkx21tm1ShkNkx21tm1Shk
• abnormal diencephalon morphology_Nkx2-1<tm1Shk>/Nkx2-1<tm1Shk>
  http://metadb.riken.jp/0000830I129S4SvJaeNkx21tm1ShkNkx21tm1ShkNkx21tm1Shk
• abnormal bronchus morphology_Nkx2-1<tm1Shk>/Nkx2-1<tm1Shk>
  http://metadb.riken.jp/0002264I129S4SvJaeNkx21tm1ShkNkx21tm1ShkNkx21tm1Shk
• absent thyroid gland_Nkx2-1<tm1Shk>/Nkx2-1<tm1Shk>
  http://metadb.riken.jp/0005314I129S4SvJaeNkx21tm1ShkNkx21tm1ShkNkx21tm1Shk
• abnormal forebrain morphology_Nkx2-1<tm1Shk>/Nkx2-1<tm1Shk>
  http://metadb.riken.jp/0000783I129S4SvJaeNkx21tm1ShkNkx21tm1ShkNkx21tm1Shk
• absent pituitary gland_Nkx2-1<tm1Shk>/Nkx2-1<tm1Shk>
  http://metadb.riken.jp/0005315I129S4SvJaeNkx21tm1ShkNkx21tm1ShkNkx21tm1Shk
• abnormal adrenal cortex morphology_Nkx2-1<tm1Shk>/Nkx2-1<tm1Shk>
  http://metadb.riken.jp/0008288I129S4SvJaeNkx21tm1ShkNkx21tm1ShkNkx21tm1Shk
• pulmonary hypoplasia_Nkx2-1<tm1Shk>/Nkx2-1<tm1Shk>
  http://metadb.riken.jp/0001178I129S4SvJaeNkx21tm1ShkNkx21tm1ShkNkx21tm1Shk
• impaired branching involved in bronchus morphogenesis_Nkx2-1<tm1Shk>/Nkx2-1<tm1Shk>
  http://metadb.riken.jp/0011028I129S4SvJaeNkx21tm1ShkNkx21tm1ShkNkx21tm1Shk