M L. Fero, et.al., A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27(Kip1)-deficient mice., Cell, 1996, 85

http://rdf.ncbi.nlm.nih.gov/pubmed/8646781

M L. Fero, et.al., A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27(Kip1)-deficient mice., Cell, 1996, 85

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Cdkn1b<tm1Mlf>
  http://metadb.riken.jp/db/mgi_rdf/MGI:1857146

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased T cell proliferation_Cdkn1b<tm1Mlf>/Cdkn1b<tm1Mlf>
  http://metadb.riken.jp/0005348I129S4SvJaeSorC57BL6JCdkn1btm1MlfCdkn1btm1MlfCdkn1btm1Mlf
• enlarged thymus_Cdkn1b<tm1Mlf>/Cdkn1b<tm1Mlf>
  http://metadb.riken.jp/0000709I129S4SvJaeSorC57BL6JCdkn1btm1MlfCdkn1btm1MlfCdkn1btm1Mlf
• thymus hyperplasia_Cdkn1b<tm1Mlf>/Cdkn1b<tm1Mlf>
  http://metadb.riken.jp/0000708I129S4SvJaeSorC57BL6JCdkn1btm1MlfCdkn1btm1MlfCdkn1btm1Mlf
• increased pituitary adenoma incidence_Cdkn1b<tm1Mlf>/Cdkn1b<tm1Mlf>
  http://metadb.riken.jp/0002041I129S4SvJaeSorC57BL6JCdkn1btm1MlfCdkn1btm1MlfCdkn1btm1Mlf
• female infertility_Cdkn1b<tm1Mlf>/Cdkn1b<tm1Mlf>
  http://metadb.riken.jp/0001926I129S4SvJaeSorC57BL6JCdkn1btm1MlfCdkn1btm1MlfCdkn1btm1Mlf
• abnormal cerebral cortex morphology_Cdkn1b<tm1Mlf>/Cdkn1b<tm1Mlf>
  http://metadb.riken.jp/0000788I129S4SvJaeSorC57BL6JCdkn1btm1MlfCdkn1btm1MlfCdkn1btm1Mlf
• increased body weight_Cdkn1b<tm1Mlf>/Cdkn1b<tm1Mlf>
  http://metadb.riken.jp/0001260I129S4SvJaeSorC57BL6JCdkn1btm1MlfCdkn1btm1MlfCdkn1btm1Mlf
• abnormal thymus morphology_Cdkn1b<tm1Mlf>/Cdkn1b<tm1Mlf>
  http://metadb.riken.jp/0000703I129S4SvJaeSorC57BL6JCdkn1btm1MlfCdkn1btm1MlfCdkn1btm1Mlf
• enlarged pituitary gland_Cdkn1b<tm1Mlf>/Cdkn1b<tm1Mlf>
  http://metadb.riken.jp/0000636I129S4SvJaeSorC57BL6JCdkn1btm1MlfCdkn1btm1MlfCdkn1btm1Mlf
• abnormal definitive hematopoiesis_Cdkn1b<tm1Mlf>/Cdkn1b<tm1Mlf>
  http://metadb.riken.jp/0002123I129S4SvJaeSorC57BL6JCdkn1btm1MlfCdkn1btm1MlfCdkn1btm1Mlf
• abnormal retinal neuronal layer morphology_Cdkn1b<tm1Mlf>/Cdkn1b<tm1Mlf>
  http://metadb.riken.jp/0006069I129S4SvJaeSorC57BL6JCdkn1btm1MlfCdkn1btm1MlfCdkn1btm1Mlf
• disorganized retinal layers_Cdkn1b<tm1Mlf>/Cdkn1b<tm1Mlf>
  http://metadb.riken.jp/0001328I129S4SvJaeSorC57BL6JCdkn1btm1MlfCdkn1btm1MlfCdkn1btm1Mlf
• pituitary gland hyperplasia_Cdkn1b<tm1Mlf>/Cdkn1b<tm1Mlf>
  http://metadb.riken.jp/0000635I129S4SvJaeSorC57BL6JCdkn1btm1MlfCdkn1btm1MlfCdkn1btm1Mlf
• abnormal hippocampus morphology_Cdkn1b<tm1Mlf>/Cdkn1b<tm1Mlf>
  http://metadb.riken.jp/0000807I129S4SvJaeSorC57BL6JCdkn1btm1MlfCdkn1btm1MlfCdkn1btm1Mlf
• enlarged spleen_Cdkn1b<tm1Mlf>/Cdkn1b<tm1Mlf>
  http://metadb.riken.jp/0000691I129S4SvJaeSorC57BL6JCdkn1btm1MlfCdkn1btm1MlfCdkn1btm1Mlf
• abnormal spleen morphology_Cdkn1b<tm1Mlf>/Cdkn1b<tm1Mlf>
  http://metadb.riken.jp/0000689I129S4SvJaeSorC57BL6JCdkn1btm1MlfCdkn1btm1MlfCdkn1btm1Mlf
• spleen hyperplasia_Cdkn1b<tm1Mlf>/Cdkn1b<tm1Mlf>
  http://metadb.riken.jp/0000693I129S4SvJaeSorC57BL6JCdkn1btm1MlfCdkn1btm1MlfCdkn1btm1Mlf
• premature death_Cdkn1b<tm1Mlf>/Cdkn1b<tm1Mlf>
  http://metadb.riken.jp/0002083I129S4SvJaeSorC57BL6JCdkn1btm1MlfCdkn1btm1MlfCdkn1btm1Mlf
• abnormal hepatocyte morphology_Cdkn1b<tm1Mlf>/Cdkn1b<tm1Mlf>
  http://metadb.riken.jp/0000607I129S4SvJaeSorC57BL6JCdkn1btm1MlfCdkn1btm1MlfCdkn1btm1Mlf
• abnormal epithalamus morphology_Cdkn1b<tm1Mlf>/Cdkn1b<tm1Mlf>
  http://metadb.riken.jp/0000840I129S4SvJaeSorC57BL6JCdkn1btm1MlfCdkn1btm1MlfCdkn1btm1Mlf
• absent corpus luteum_Cdkn1b<tm1Mlf>/Cdkn1b<tm1Mlf>
  http://metadb.riken.jp/0001134I129S4SvJaeSorC57BL6JCdkn1btm1MlfCdkn1btm1MlfCdkn1btm1Mlf

class

http://purl.org/net/cito/citesAsAuthority

• Cdkn1b<tm1Mlf>
  http://metadb.riken.jp/db/mgi_rdf/MGI:1857146