J D. Hardin, et.al., Transgenes encoding both type I and type IV c-abl proteins rescue the lethality of c-abl mutant mice., Oncogene, 1996, 12

http://rdf.ncbi.nlm.nih.gov/pubmed/8700526

J D. Hardin, et.al., Transgenes encoding both type I and type IV c-abl proteins rescue the lethality of c-abl mutant mice., Oncogene, 1996, 12

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(ACTB-Abl1*I)1Spg
  http://metadb.riken.jp/db/mgi_rdf/MGI:4361569
• Tg(ACTB-Abl1*IV)1Spg
  http://metadb.riken.jp/db/mgi_rdf/MGI:4361572
• Tg(ACTB-Abl1*K290R)1Spg
  http://metadb.riken.jp/db/mgi_rdf/MGI:4361573

class

http://purl.org/net/cito/citesAsAuthority

• Tg(ACTB-Abl1*I)1Spg
  http://metadb.riken.jp/db/mgi_rdf/MGI:4361569
• Tg(ACTB-Abl1*IV)1Spg
  http://metadb.riken.jp/db/mgi_rdf/MGI:4361572
• Tg(ACTB-Abl1*K290R)1Spg
  http://metadb.riken.jp/db/mgi_rdf/MGI:4361573

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased survivor rate_Abl1<tm1Mlg>/Abl1<tm1Mlg>,Tg(ACTB-Abl1*K290R)1Spg/0
  http://metadb.riken.jp/0008770I129SSvEvCBAC57BL6JAbl1tm1MlgAbl1tm1MlgTgACTBAbl1K290R1Spg0Abl1tm1MlgTgACTBAbl1K290R1Spg
• decreased bone marrow cell number_Abl1<tm1Mlg>/Abl1<tm1Mlg>,Tg(ACTB-Abl1*I)1Spg/0
  http://metadb.riken.jp/0000333I129SSvEvCBAC57BL6JAbl1tm1MlgAbl1tm1MlgTgACTBAbl1I1Spg0TgACTBAbl1I1SpgAbl1tm1Mlg
• decreased survivor rate_Abl1<tm1Mlg>/Abl1<tm1Mlg>
  http://metadb.riken.jp/0008770I129SSvEvCBAC57BL6JAbl1tm1MlgAbl1tm1MlgAbl1tm1Mlg
• abnormal spleen morphology_Abl1<tm1Mlg>/Abl1<tm1Mlg>,Tg(ACTB-Abl1*K290R)1Spg/0
  http://metadb.riken.jp/0000689I129SSvEvCBAC57BL6JAbl1tm1MlgAbl1tm1MlgTgACTBAbl1K290R1Spg0Abl1tm1MlgTgACTBAbl1K290R1Spg
• decreased bone marrow cell number_Abl1<tm1Mlg>/Abl1<tm1Mlg>
  http://metadb.riken.jp/0000333I129SSvEvCBAC57BL6JAbl1tm1MlgAbl1tm1MlgAbl1tm1Mlg
• increased susceptibility to infection_Abl1<tm1Mlg>/Abl1<tm1Mlg>
  http://metadb.riken.jp/0002406I129SSvEvCBAC57BL6JAbl1tm1MlgAbl1tm1MlgAbl1tm1Mlg
• postnatal lethality, incomplete penetrance_Abl1<tm1Mlg>/Abl1<tm1Mlg>,Tg(ACTB-Abl1*K290R)1Spg/0
  http://metadb.riken.jp/0011086I129SSvEvCBAC57BL6JAbl1tm1MlgAbl1tm1MlgTgACTBAbl1K290R1Spg0Abl1tm1MlgTgACTBAbl1K290R1Spg
• rectal prolapse_Abl1<tm1Mlg>/Abl1<tm1Mlg>
  http://metadb.riken.jp/0000493I129SSvEvCBAC57BL6JAbl1tm1MlgAbl1tm1MlgAbl1tm1Mlg
• abnormal spleen morphology_Abl1<tm1Mlg>/Abl1<tm1Mlg>
  http://metadb.riken.jp/0000689I129SSvEvCBAC57BL6JAbl1tm1MlgAbl1tm1MlgAbl1tm1Mlg
• abnormal eye morphology_Abl1<tm1Mlg>/Abl1<tm1Mlg>
  http://metadb.riken.jp/0002092I129SSvEvCBAC57BL6JAbl1tm1MlgAbl1tm1MlgAbl1tm1Mlg
• decreased body size_Abl1<tm1Mlg>/Abl1<tm1Mlg>
  http://metadb.riken.jp/0001265I129SSvEvCBAC57BL6JAbl1tm1MlgAbl1tm1MlgAbl1tm1Mlg
• postnatal lethality, incomplete penetrance_Abl1<tm1Mlg>/Abl1<tm1Mlg>
  http://metadb.riken.jp/0011086I129SSvEvCBAC57BL6JAbl1tm1MlgAbl1tm1MlgAbl1tm1Mlg
• decreased cranium height_Abl1<tm1Mlg>/Abl1<tm1Mlg>
  http://metadb.riken.jp/0008525I129SSvEvCBAC57BL6JAbl1tm1MlgAbl1tm1MlgAbl1tm1Mlg
• decreased bone marrow cell number_Abl1<tm1Mlg>/Abl1<tm1Mlg>,Tg(ACTB-Abl1*IV)1Spg/0
  http://metadb.riken.jp/0000333I129SSvEvCBAC57BL6JAbl1tm1MlgAbl1tm1MlgTgACTBAbl1IV1Spg0Abl1tm1MlgTgACTBAbl1IV1Spg
• increased susceptibility to infection_Abl1<tm1Mlg>/Abl1<tm1Mlg>,Tg(ACTB-Abl1*K290R)1Spg/0
  http://metadb.riken.jp/0002406I129SSvEvCBAC57BL6JAbl1tm1MlgAbl1tm1MlgTgACTBAbl1K290R1Spg0Abl1tm1MlgTgACTBAbl1K290R1Spg
• abnormal digestive system morphology_Abl1<tm1Mlg>/Abl1<tm1Mlg>,Tg(ACTB-Abl1*K290R)1Spg/0
  http://metadb.riken.jp/0000462I129SSvEvCBAC57BL6JAbl1tm1MlgAbl1tm1MlgTgACTBAbl1K290R1Spg0Abl1tm1MlgTgACTBAbl1K290R1Spg