S R. McKercher, et.al., Targeted disruption of the PU.1 gene results in multiple hematopoietic abnormalities., The EMBO journal, 1996, 15

http://rdf.ncbi.nlm.nih.gov/pubmed/8896458

S R. McKercher, et.al., Targeted disruption of the PU.1 gene results in multiple hematopoietic abnormalities., The EMBO journal, 1996, 15

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Spi1<tm1Ram>
  http://metadb.riken.jp/db/mgi_rdf/MGI:1927876

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal B cell number_Spi1<tm1Ram>/Spi1<tm1Ram>
  http://metadb.riken.jp/0002458I129S2SvPasC57BL6Spi1tm1RamSpi1tm1RamSpi1tm1Ram
• decreased macrophage cell number_Spi1<tm1Ram>/Spi1<tm1Ram>
  http://metadb.riken.jp/0003884I129S2SvPasC57BL6Spi1tm1RamSpi1tm1RamSpi1tm1Ram
• absent mature B cells_Spi1<tm1Ram>/Spi1<tm1Ram>
  http://metadb.riken.jp/0008212I129S2SvPasC57BL6Spi1tm1RamSpi1tm1RamSpi1tm1Ram
• neonatal lethality, complete penetrance_Spi1<tm1Ram>/Spi1<tm1Ram>
  http://metadb.riken.jp/0011087I129S2SvPasC57BL6Spi1tm1RamSpi1tm1RamSpi1tm1Ram
• abnormal macrophage differentiation_Spi1<tm1Ram>/Spi1<tm1Ram>
  http://metadb.riken.jp/0008113I129S2SvPasC57BL6Spi1tm1RamSpi1tm1RamSpi1tm1Ram
• decreased CD8-positive, alpha-beta T cell number_Spi1<tm1Ram>/Spi1<tm1Ram>
  http://metadb.riken.jp/0008079I129S2SvPasC57BL6Spi1tm1RamSpi1tm1RamSpi1tm1Ram
• abnormal T cell number_Spi1<tm1Ram>/Spi1<tm1Ram>
  http://metadb.riken.jp/0006387I129S2SvPasC57BL6Spi1tm1RamSpi1tm1RamSpi1tm1Ram
• decreased CD4-positive, alpha beta T cell number_Spi1<tm1Ram>/Spi1<tm1Ram>
  http://metadb.riken.jp/0008075I129S2SvPasC57BL6Spi1tm1RamSpi1tm1RamSpi1tm1Ram
• decreased neutrophil cell number_Spi1<tm1Ram>/Spi1<tm1Ram>
  http://metadb.riken.jp/0000222I129S2SvPasC57BL6Spi1tm1RamSpi1tm1RamSpi1tm1Ram
• sepsis_Spi1<tm1Ram>/Spi1<tm1Ram>
  http://metadb.riken.jp/0005044I129S2SvPasC57BL6Spi1tm1RamSpi1tm1RamSpi1tm1Ram
• decreased spleen red pulp amount_Spi1<tm1Ram>/Spi1<tm1Ram>
  http://metadb.riken.jp/0008477I129S2SvPasC57BL6Spi1tm1RamSpi1tm1RamSpi1tm1Ram
• abnormal neutrophil differentiation_Spi1<tm1Ram>/Spi1<tm1Ram>
  http://metadb.riken.jp/0002415I129S2SvPasC57BL6Spi1tm1RamSpi1tm1RamSpi1tm1Ram
• abnormal T cell differentiation_Spi1<tm1Ram>/Spi1<tm1Ram>
  http://metadb.riken.jp/0002145I129S2SvPasC57BL6Spi1tm1RamSpi1tm1RamSpi1tm1Ram
• decreased thymocyte number_Spi1<tm1Ram>/Spi1<tm1Ram>
  http://metadb.riken.jp/0000715I129S2SvPasC57BL6Spi1tm1RamSpi1tm1RamSpi1tm1Ram
• abnormal liver morphology_Spi1<tm1Ram>/Spi1<tm1Ram>
  http://metadb.riken.jp/0000598I129S2SvPasC57BL6Spi1tm1RamSpi1tm1RamSpi1tm1Ram
• decreased double-positive T cell number_Spi1<tm1Ram>/Spi1<tm1Ram>
  http://metadb.riken.jp/0005092I129S2SvPasC57BL6Spi1tm1RamSpi1tm1RamSpi1tm1Ram

class

http://purl.org/net/cito/citesAsAuthority

• Spi1<tm1Ram>
  http://metadb.riken.jp/db/mgi_rdf/MGI:1927876