N. Jena, et.al., BMP7 null mutation in mice: developmental defects in skeleton, kidney, and eye., Experimental cell research, 1997, 230

http://rdf.ncbi.nlm.nih.gov/pubmed/9013703

N. Jena, et.al., BMP7 null mutation in mice: developmental defects in skeleton, kidney, and eye., Experimental cell research, 1997, 230

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Bmp7<Tg(BCL2)114Cro>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2158467

class

http://purl.org/net/cito/citesAsAuthority

• Bmp7<Tg(BCL2)114Cro>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2158467

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased bone mineral density_Bmp7<Tg(BCL2)114Cro>/Bmp7<Tg(BCL2)114Cro>
  http://metadb.riken.jp/0000063IC3HHeJC57BL6Bmp7TgBCL2114CroBmp7TgBCL2114CroBmp7TgBCL2114Cro
• fusion of vertebral bodies_Bmp7<Tg(BCL2)114Cro>/Bmp7<Tg(BCL2)114Cro>
  http://metadb.riken.jp/0004612IC3HHeJC57BL6Bmp7TgBCL2114CroBmp7TgBCL2114CroBmp7TgBCL2114Cro
• rib fusion_Bmp7<Tg(BCL2)114Cro>/Bmp7<Tg(BCL2)114Cro>
  http://metadb.riken.jp/0000154IC3HHeJC57BL6Bmp7TgBCL2114CroBmp7TgBCL2114CroBmp7TgBCL2114Cro
• abnormal distal convoluted tubule morphology_Bmp7<Tg(BCL2)114Cro>/Bmp7<Tg(BCL2)114Cro>
  http://metadb.riken.jp/0004757IC3HHeJC57BL6Bmp7TgBCL2114CroBmp7TgBCL2114CroBmp7TgBCL2114Cro
• impaired coordination_Bmp7<Tg(BCL2)114Cro>/Bmp7<Tg(BCL2)114Cro>
  http://metadb.riken.jp/0001405IC3HHeJC57BL6Bmp7TgBCL2114CroBmp7TgBCL2114CroBmp7TgBCL2114Cro
• tremors_Bmp7<Tg(BCL2)114Cro>/Bmp7<Tg(BCL2)114Cro>
  http://metadb.riken.jp/0000745IC3HHeJC57BL6Bmp7TgBCL2114CroBmp7TgBCL2114CroBmp7TgBCL2114Cro
• abnormal kidney development_Bmp7<Tg(BCL2)114Cro>/Bmp7<Tg(BCL2)114Cro>
  http://metadb.riken.jp/0000527IC3HHeJC57BL6Bmp7TgBCL2114CroBmp7TgBCL2114CroBmp7TgBCL2114Cro
• abnormal retinal pigment epithelium morphology_Bmp7<Tg(BCL2)114Cro>/Bmp7<Tg(BCL2)114Cro>
  http://metadb.riken.jp/0005201IC3HHeJC57BL6Bmp7TgBCL2114CroBmp7TgBCL2114CroBmp7TgBCL2114Cro
• decreased birth weight_Bmp7<Tg(BCL2)114Cro>/Bmp7<Tg(BCL2)114Cro>
  http://metadb.riken.jp/0009674IC3HHeJC57BL6Bmp7TgBCL2114CroBmp7TgBCL2114CroBmp7TgBCL2114Cro
• xiphoid process foramen_Bmp7<Tg(BCL2)114Cro>/Bmp7<Tg(BCL2)114Cro>
  http://metadb.riken.jp/0004679IC3HHeJC57BL6Bmp7TgBCL2114CroBmp7TgBCL2114CroBmp7TgBCL2114Cro
• neonatal lethality, incomplete penetrance_Bmp7<Tg(BCL2)114Cro>/Bmp7<Tg(BCL2)114Cro>
  http://metadb.riken.jp/0011088IC3HHeJC57BL6Bmp7TgBCL2114CroBmp7TgBCL2114CroBmp7TgBCL2114Cro
• polycystic kidney_Bmp7<Tg(BCL2)114Cro>/Bmp7<Tg(BCL2)114Cro>
  http://metadb.riken.jp/0008528IC3HHeJC57BL6Bmp7TgBCL2114CroBmp7TgBCL2114CroBmp7TgBCL2114Cro
• basisphenoid bone foramen_Bmp7<Tg(BCL2)114Cro>/Bmp7<Tg(BCL2)114Cro>
  http://metadb.riken.jp/0004463IC3HHeJC57BL6Bmp7TgBCL2114CroBmp7TgBCL2114CroBmp7TgBCL2114Cro
• decreased nephron number_Bmp7<Tg(BCL2)114Cro>/Bmp7<Tg(BCL2)114Cro>
  http://metadb.riken.jp/0011290IC3HHeJC57BL6Bmp7TgBCL2114CroBmp7TgBCL2114CroBmp7TgBCL2114Cro
• abnormal retinal pigmentation_Bmp7<Tg(BCL2)114Cro>/Bmp7<Tg(BCL2)114Cro>
  http://metadb.riken.jp/0005103IC3HHeJC57BL6Bmp7TgBCL2114CroBmp7TgBCL2114CroBmp7TgBCL2114Cro
• premature death_Bmp7<Tg(BCL2)114Cro>/Bmp7<Tg(BCL2)114Cro>
  http://metadb.riken.jp/0002083IC3HHeJC57BL6Bmp7TgBCL2114CroBmp7TgBCL2114CroBmp7TgBCL2114Cro
• polydactyly_Bmp7<Tg(BCL2)114Cro>/Bmp7<Tg(BCL2)114Cro>
  http://metadb.riken.jp/0000562IC3HHeJC57BL6Bmp7TgBCL2114CroBmp7TgBCL2114CroBmp7TgBCL2114Cro
• abnormal sacral vertebrae morphology_Bmp7<Tg(BCL2)114Cro>/Bmp7<Tg(BCL2)114Cro>
  http://metadb.riken.jp/0003050IC3HHeJC57BL6Bmp7TgBCL2114CroBmp7TgBCL2114CroBmp7TgBCL2114Cro
• kinked tail_Bmp7<Tg(BCL2)114Cro>/Bmp7<Tg(BCL2)114Cro>
  http://metadb.riken.jp/0000585IC3HHeJC57BL6Bmp7TgBCL2114CroBmp7TgBCL2114CroBmp7TgBCL2114Cro
• aphakia_Bmp7<Tg(BCL2)114Cro>/Bmp7<Tg(BCL2)114Cro>
  http://metadb.riken.jp/0003078IC3HHeJC57BL6Bmp7TgBCL2114CroBmp7TgBCL2114CroBmp7TgBCL2114Cro
• abnormal vertebrae morphology_Bmp7<Tg(BCL2)114Cro>/Bmp7<Tg(BCL2)114Cro>
  http://metadb.riken.jp/0000137IC3HHeJC57BL6Bmp7TgBCL2114CroBmp7TgBCL2114CroBmp7TgBCL2114Cro
• decreased lumbar vertebrae number_Bmp7<Tg(BCL2)114Cro>/Bmp7<Tg(BCL2)114Cro>
  http://metadb.riken.jp/0004647IC3HHeJC57BL6Bmp7TgBCL2114CroBmp7TgBCL2114CroBmp7TgBCL2114Cro
• eyelids fail to open_Bmp7<Tg(BCL2)114Cro>/Bmp7<Tg(BCL2)114Cro>
  http://metadb.riken.jp/0005176IC3HHeJC57BL6Bmp7TgBCL2114CroBmp7TgBCL2114CroBmp7TgBCL2114Cro
• small kidney_Bmp7<Tg(BCL2)114Cro>/Bmp7<Tg(BCL2)114Cro>
  http://metadb.riken.jp/0002989IC3HHeJC57BL6Bmp7TgBCL2114CroBmp7TgBCL2114CroBmp7TgBCL2114Cro
• abnormal skeleton morphology_Bmp7<Tg(BCL2)114Cro>/Bmp7<Tg(BCL2)114Cro>
  http://metadb.riken.jp/0005508IC3HHeJC57BL6Bmp7TgBCL2114CroBmp7TgBCL2114CroBmp7TgBCL2114Cro
• delayed bone ossification_Bmp7<Tg(BCL2)114Cro>/Bmp7<Tg(BCL2)114Cro>
  http://metadb.riken.jp/0000060IC3HHeJC57BL6Bmp7TgBCL2114CroBmp7TgBCL2114CroBmp7TgBCL2114Cro