F. Borriello, et.al., B7-1 and B7-2 have overlapping, critical roles in immunoglobulin class switching and germinal center formation., Immunity, 1997, 6

http://rdf.ncbi.nlm.nih.gov/pubmed/9075931

F. Borriello, et.al., B7-1 and B7-2 have overlapping, critical roles in immunoglobulin class switching and germinal center formation., Immunity, 1997, 6

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Cd86<tm1Shr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:1861805
• Cd86<tm2Shr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2159105

class

http://purl.org/net/cito/citesAsAuthority

• Cd86<tm1Shr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:1861805
• Cd86<tm2Shr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2159105

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased IgG3 level_Cd80<tm1Shr>/Cd80<tm1Shr>,Cd86<tm2Shr>/Cd86<tm2Shr>
  http://metadb.riken.jp/0008502I129S4SvJaeCd80tm1ShrCd80tm1ShrCd86tm2ShrCd86tm2ShrCd80tm1ShrCd86tm2Shr
• abnormal immunoglobulin level_Cd80<tm1Shr>/Cd80<tm1Shr>
  http://metadb.riken.jp/0002490I129S4SvJaeCd80tm1ShrCd80tm1ShrCd80tm1Shr
• absent spleen germinal center_Cd86<tm1Shr>/Cd86<tm1Shr>
  http://metadb.riken.jp/0008474I129S4SvJaeCd86tm1ShrCd86tm1ShrCd86tm1Shr
• decreased IgG level_Cd80<tm1Shr>/Cd80<tm1Shr>,Cd86<tm2Shr>/Cd86<tm2Shr>
  http://metadb.riken.jp/0001805I129S4SvJaeCd80tm1ShrCd80tm1ShrCd86tm2ShrCd86tm2ShrCd80tm1ShrCd86tm2Shr
• increased IgM level_Cd80<tm1Shr>/Cd80<tm1Shr>,Cd86<tm2Shr>/Cd86<tm2Shr>
  http://metadb.riken.jp/0002494I129S4SvJaeCd80tm1ShrCd80tm1ShrCd86tm2ShrCd86tm2ShrCd80tm1ShrCd86tm2Shr
• abnormal humoral immune response_Cd86<tm1Shr>/Cd86<tm1Shr>
  http://metadb.riken.jp/0001800I129S4SvJaeCd86tm1ShrCd86tm1ShrCd86tm1Shr
• decreased IgG1 level_Cd80<tm1Shr>/Cd80<tm1Shr>,Cd86<tm2Shr>/Cd86<tm2Shr>
  http://metadb.riken.jp/0008495I129S4SvJaeCd80tm1ShrCd80tm1ShrCd86tm2ShrCd86tm2ShrCd80tm1ShrCd86tm2Shr
• decreased IgG level_Cd86<tm1Shr>/Cd86<tm1Shr>
  http://metadb.riken.jp/0001805I129S4SvJaeCd86tm1ShrCd86tm1ShrCd86tm1Shr
• abnormal spleen morphology_Cd80<tm1Shr>/Cd80<tm1Shr>,Cd86<tm2Shr>/Cd86<tm2Shr>
  http://metadb.riken.jp/0000689I129S4SvJaeCd80tm1ShrCd80tm1ShrCd86tm2ShrCd86tm2ShrCd80tm1ShrCd86tm2Shr
• decreased IgG2a level_Cd80<tm1Shr>/Cd80<tm1Shr>,Cd86<tm2Shr>/Cd86<tm2Shr>
  http://metadb.riken.jp/0008496I129S4SvJaeCd80tm1ShrCd80tm1ShrCd86tm2ShrCd86tm2ShrCd80tm1ShrCd86tm2Shr
• abnormal lymph node B cell domain morphology_Cd80<tm1Shr>/Cd80<tm1Shr>,Cd86<tm2Shr>/Cd86<tm2Shr>
  http://metadb.riken.jp/0002344I129S4SvJaeCd80tm1ShrCd80tm1ShrCd86tm2ShrCd86tm2ShrCd80tm1ShrCd86tm2Shr