T. Komori, et.al., Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts., Cell, 1997, 89

http://rdf.ncbi.nlm.nih.gov/pubmed/9182763

T. Komori, et.al., Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts., Cell, 1997, 89

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Runx2<tm1Kish>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176466

class

http://purl.org/net/cito/citesAsAuthority

• Runx2<tm1Kish>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176466

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal dermal layer morphology_Runx2<tm1Kish>/Runx2<tm1Kish>
  http://metadb.riken.jp/0001243I129P2OlaHsdC57BL6Runx2tm1KishRunx2tm1KishRunx2tm1Kish
• short limbs_Runx2<tm1Kish>/Runx2<tm1Kish>
  http://metadb.riken.jp/0000547I129P2OlaHsdC57BL6Runx2tm1KishRunx2tm1KishRunx2tm1Kish
• abnormal long bone epiphyseal ossification zone morphology_Runx2<tm1Kish>/Runx2<tm1Kish>
  http://metadb.riken.jp/0006399I129P2OlaHsdC57BL6Runx2tm1KishRunx2tm1KishRunx2tm1Kish
• abnormal osteoclast differentiation_Runx2<tm1Kish>/Runx2<tm1Kish>
  http://metadb.riken.jp/0008396I129P2OlaHsdC57BL6Runx2tm1KishRunx2tm1KishRunx2tm1Kish
• abnormal parietal bone morphology_Runx2<tm1Kish>/Runx2<+>
  http://metadb.riken.jp/0000109I129P2OlaHsdC57BL6Runx2tm1KishRunx2Runx2Runx2tm1Kish
• neonatal lethality, complete penetrance_Runx2<tm1Kish>/Runx2<tm1Kish>
  http://metadb.riken.jp/0011087I129P2OlaHsdC57BL6Runx2tm1KishRunx2tm1KishRunx2tm1Kish
• respiratory failure_Runx2<tm1Kish>/Runx2<tm1Kish>
  http://metadb.riken.jp/0001953I129P2OlaHsdC57BL6Runx2tm1KishRunx2tm1KishRunx2tm1Kish
• abnormal femur morphology_Runx2<tm1Kish>/Runx2<tm1Kish>
  http://metadb.riken.jp/0000559I129P2OlaHsdC57BL6Runx2tm1KishRunx2tm1KishRunx2tm1Kish
• abnormal skeleton development_Runx2<tm1Kish>/Runx2<tm1Kish>
  http://metadb.riken.jp/0002113I129P2OlaHsdC57BL6Runx2tm1KishRunx2tm1KishRunx2tm1Kish
• cyanosis_Runx2<tm1Kish>/Runx2<tm1Kish>
  http://metadb.riken.jp/0001575I129P2OlaHsdC57BL6Runx2tm1KishRunx2tm1KishRunx2tm1Kish
• abnormal bone ossification_Runx2<tm1Kish>/Runx2<tm1Kish>
  http://metadb.riken.jp/0008271I129P2OlaHsdC57BL6Runx2tm1KishRunx2tm1KishRunx2tm1Kish
• abnormal neurocranium morphology_Runx2<tm1Kish>/Runx2<tm1Kish>
  http://metadb.riken.jp/0000074I129P2OlaHsdC57BL6Runx2tm1KishRunx2tm1KishRunx2tm1Kish
• abnormal tibia morphology_Runx2<tm1Kish>/Runx2<tm1Kish>
  http://metadb.riken.jp/0000558I129P2OlaHsdC57BL6Runx2tm1KishRunx2tm1KishRunx2tm1Kish
• abnormal supraoccipital bone morphology_Runx2<tm1Kish>/Runx2<+>
  http://metadb.riken.jp/0000078I129P2OlaHsdC57BL6Runx2tm1KishRunx2Runx2Runx2tm1Kish
• abnormal osteoblast differentiation_Runx2<tm1Kish>/Runx2<tm1Kish>
  http://metadb.riken.jp/0008395I129P2OlaHsdC57BL6Runx2tm1KishRunx2tm1KishRunx2tm1Kish
• nasal bone hypoplasia_Runx2<tm1Kish>/Runx2<+>
  http://metadb.riken.jp/0000103I129P2OlaHsdC57BL6Runx2tm1KishRunx2Runx2Runx2tm1Kish
• decreased body weight_Runx2<tm1Kish>/Runx2<tm1Kish>
  http://metadb.riken.jp/0001262I129P2OlaHsdC57BL6Runx2tm1KishRunx2tm1KishRunx2tm1Kish
• clavicle hypoplasia_Runx2<tm1Kish>/Runx2<+>
  http://metadb.riken.jp/0004337I129P2OlaHsdC57BL6Runx2tm1KishRunx2Runx2Runx2tm1Kish
• disproportionate dwarf_Runx2<tm1Kish>/Runx2<tm1Kish>
  http://metadb.riken.jp/0002427I129P2OlaHsdC57BL6Runx2tm1KishRunx2tm1KishRunx2tm1Kish
• decreased thymocyte number_Runx2<tm1Kish>/Runx2<tm1Kish>
  http://metadb.riken.jp/0000715I129P2OlaHsdC57BL6Runx2tm1KishRunx2tm1KishRunx2tm1Kish
• abnormal interparietal bone morphology_Runx2<tm1Kish>/Runx2<+>
  http://metadb.riken.jp/0000077I129P2OlaHsdC57BL6Runx2tm1KishRunx2Runx2Runx2tm1Kish
• abnormal bone marrow cavity morphology_Runx2<tm1Kish>/Runx2<tm1Kish>
  http://metadb.riken.jp/0000065I129P2OlaHsdC57BL6Runx2tm1KishRunx2tm1KishRunx2tm1Kish