F. Otto, et.al., Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development., Cell, 1997, 89

http://rdf.ncbi.nlm.nih.gov/pubmed/9182764

F. Otto, et.al., Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development., Cell, 1997, 89

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Runx2<tm1Mjo>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176465

class

http://purl.org/net/cito/citesAsAuthority

• Runx2<tm1Mjo>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176465

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• delayed endochondral bone ossification_Runx2<tm1Mjo>/Runx2<tm1Mjo>
  http://metadb.riken.jp/0003419I129S1Sv129X1SvJC57BL6Runx2tm1MjoRunx2tm1MjoRunx2tm1Mjo
• abnormal lung volume_Runx2<tm1Mjo>/Runx2<tm1Mjo>
  http://metadb.riken.jp/0001942I129S1Sv129X1SvJC57BL6Runx2tm1MjoRunx2tm1MjoRunx2tm1Mjo
• abnormal tooth development_Runx2<tm1Mjo>/Runx2<tm1Mjo>
  http://metadb.riken.jp/0000116I129S1Sv129X1SvJC57BL6Runx2tm1MjoRunx2tm1MjoRunx2tm1Mjo
• decreased body size_Runx2<tm1Mjo>/Runx2<tm1Mjo>
  http://metadb.riken.jp/0001265I129S1Sv129X1SvJC57BL6Runx2tm1MjoRunx2tm1MjoRunx2tm1Mjo
• delayed intramembranous bone ossification_Runx2<tm1Mjo>/Runx2<+>
  http://metadb.riken.jp/0003420I129S1Sv129X1SvJC57BL6Runx2tm1MjoRunx2Runx2tm1MjoRunx2
• delayed endochondral bone ossification_Runx2<tm1Mjo>/Runx2<+>
  http://metadb.riken.jp/0003419I129S1Sv129X1SvJC57BL6Runx2tm1MjoRunx2Runx2tm1MjoRunx2
• abnormal cartilage development_Runx2<tm1Mjo>/Runx2<tm1Mjo>
  http://metadb.riken.jp/0000164I129S1Sv129X1SvJC57BL6Runx2tm1MjoRunx2tm1MjoRunx2tm1Mjo
• clavicle hypoplasia_Runx2<tm1Mjo>/Runx2<+>
  http://metadb.riken.jp/0004337I129S1Sv129X1SvJC57BL6Runx2tm1MjoRunx2Runx2tm1MjoRunx2
• abnormal long bone epiphyseal plate morphology_Runx2<tm1Mjo>/Runx2<+>
  http://metadb.riken.jp/0003055I129S1Sv129X1SvJC57BL6Runx2tm1MjoRunx2Runx2tm1MjoRunx2
• decreased body weight_Runx2<tm1Mjo>/Runx2<tm1Mjo>
  http://metadb.riken.jp/0001262I129S1Sv129X1SvJC57BL6Runx2tm1MjoRunx2tm1MjoRunx2tm1Mjo
• abnormal osteoblast differentiation_Runx2<tm1Mjo>/Runx2<+>
  http://metadb.riken.jp/0008395I129S1Sv129X1SvJC57BL6Runx2tm1MjoRunx2Runx2tm1MjoRunx2
• parietal bone hypoplasia_Runx2<tm1Mjo>/Runx2<+>
  http://metadb.riken.jp/0004420I129S1Sv129X1SvJC57BL6Runx2tm1MjoRunx2Runx2tm1MjoRunx2
• abnormal tooth development_Runx2<tm1Mjo>/Runx2<+>
  http://metadb.riken.jp/0000116I129S1Sv129X1SvJC57BL6Runx2tm1MjoRunx2Runx2tm1MjoRunx2
• absent bone marrow cell_Runx2<tm1Mjo>/Runx2<tm1Mjo>
  http://metadb.riken.jp/0000175I129S1Sv129X1SvJC57BL6Runx2tm1MjoRunx2tm1MjoRunx2tm1Mjo
• pulmonary vascular congestion_Runx2<tm1Mjo>/Runx2<tm1Mjo>
  http://metadb.riken.jp/0010018I129S1Sv129X1SvJC57BL6Runx2tm1MjoRunx2tm1MjoRunx2tm1Mjo
• decreased osteoblast cell number_Runx2<tm1Mjo>/Runx2<tm1Mjo>
  http://metadb.riken.jp/0004989I129S1Sv129X1SvJC57BL6Runx2tm1MjoRunx2tm1MjoRunx2tm1Mjo
• absent deltoid tuberosity_Runx2<tm1Mjo>/Runx2<+>
  http://metadb.riken.jp/0004354I129S1Sv129X1SvJC57BL6Runx2tm1MjoRunx2Runx2tm1MjoRunx2
• abnormal fontanelle morphology_Runx2<tm1Mjo>/Runx2<+>
  http://metadb.riken.jp/0000084I129S1Sv129X1SvJC57BL6Runx2tm1MjoRunx2Runx2tm1MjoRunx2
• interparietal bone hypoplasia_Runx2<tm1Mjo>/Runx2<+>
  http://metadb.riken.jp/0004385I129S1Sv129X1SvJC57BL6Runx2tm1MjoRunx2Runx2tm1MjoRunx2
• pubis hypoplasia_Runx2<tm1Mjo>/Runx2<+>
  http://metadb.riken.jp/0004693I129S1Sv129X1SvJC57BL6Runx2tm1MjoRunx2Runx2tm1MjoRunx2
• abnormal cranium morphology_Runx2<tm1Mjo>/Runx2<tm1Mjo>
  http://metadb.riken.jp/0000438I129S1Sv129X1SvJC57BL6Runx2tm1MjoRunx2tm1MjoRunx2tm1Mjo
• respiratory failure_Runx2<tm1Mjo>/Runx2<tm1Mjo>
  http://metadb.riken.jp/0001953I129S1Sv129X1SvJC57BL6Runx2tm1MjoRunx2tm1MjoRunx2tm1Mjo
• abnormal bone ossification_Runx2<tm1Mjo>/Runx2<tm1Mjo>
  http://metadb.riken.jp/0008271I129S1Sv129X1SvJC57BL6Runx2tm1MjoRunx2tm1MjoRunx2tm1Mjo
• abnormal clavicle morphology_Runx2<tm1Mjo>/Runx2<tm1Mjo>
  http://metadb.riken.jp/0005298I129S1Sv129X1SvJC57BL6Runx2tm1MjoRunx2tm1MjoRunx2tm1Mjo
• increased nucleated erythrocyte cell number_Runx2<tm1Mjo>/Runx2<tm1Mjo>
  http://metadb.riken.jp/0009395I129S1Sv129X1SvJC57BL6Runx2tm1MjoRunx2tm1MjoRunx2tm1Mjo
• abnormal cartilage morphology_Runx2<tm1Mjo>/Runx2<+>
  http://metadb.riken.jp/0000163I129S1Sv129X1SvJC57BL6Runx2tm1MjoRunx2Runx2tm1MjoRunx2
• neonatal lethality, complete penetrance_Runx2<tm1Mjo>/Runx2<tm1Mjo>
  http://metadb.riken.jp/0011087I129S1Sv129X1SvJC57BL6Runx2tm1MjoRunx2tm1MjoRunx2tm1Mjo
• ischium hypoplasia_Runx2<tm1Mjo>/Runx2<+>
  http://metadb.riken.jp/0004690I129S1Sv129X1SvJC57BL6Runx2tm1MjoRunx2Runx2tm1MjoRunx2
• abnormal nose morphology_Runx2<tm1Mjo>/Runx2<tm1Mjo>
  http://metadb.riken.jp/0002233I129S1Sv129X1SvJC57BL6Runx2tm1MjoRunx2tm1MjoRunx2tm1Mjo
• abnormal humerus morphology_Runx2<tm1Mjo>/Runx2<+>
  http://metadb.riken.jp/0005296I129S1Sv129X1SvJC57BL6Runx2tm1MjoRunx2Runx2tm1MjoRunx2
• abnormal xiphoid process morphology_Runx2<tm1Mjo>/Runx2<+>
  http://metadb.riken.jp/0000159I129S1Sv129X1SvJC57BL6Runx2tm1MjoRunx2Runx2tm1MjoRunx2
• delayed intramembranous bone ossification_Runx2<tm1Mjo>/Runx2<tm1Mjo>
  http://metadb.riken.jp/0003420I129S1Sv129X1SvJC57BL6Runx2tm1MjoRunx2tm1MjoRunx2tm1Mjo
• hyoid bone hypoplasia_Runx2<tm1Mjo>/Runx2<+>
  http://metadb.riken.jp/0009899I129S1Sv129X1SvJC57BL6Runx2tm1MjoRunx2Runx2tm1MjoRunx2
• abnormal cranial suture morphology_Runx2<tm1Mjo>/Runx2<+>
  http://metadb.riken.jp/0002835I129S1Sv129X1SvJC57BL6Runx2tm1MjoRunx2Runx2tm1MjoRunx2