M. Furuta, et.al., Defective prohormone processing and altered pancreatic islet morphology in mice lacking active SPC2., Proceedings of the National Academy of Sciences of the United States of America, 1997, 94

http://rdf.ncbi.nlm.nih.gov/pubmed/9192619

M. Furuta, et.al., Defective prohormone processing and altered pancreatic islet morphology in mice lacking active SPC2., Proceedings of the National Academy of Sciences of the United States of America, 1997, 94

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Pcsk2<tm1Dfs>
  http://metadb.riken.jp/db/mgi_rdf/MGI:1857445

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased circulating insulin level_Pcsk2<tm1Dfs>/Pcsk2<tm1Dfs>
  http://metadb.riken.jp/0002727I129S1Sv129X1SvJC57BL6Pcsk2tm1DfsPcsk2tm1DfsPcsk2tm1Dfs
• decreased glucagon secretion_Pcsk2<tm1Dfs>/Pcsk2<tm1Dfs>
  http://metadb.riken.jp/0002711I129S1Sv129X1SvJC57BL6Pcsk2tm1DfsPcsk2tm1DfsPcsk2tm1Dfs
• abnormal gland physiology_Pcsk2<tm1Dfs>/Pcsk2<tm1Dfs>
  http://metadb.riken.jp/0002164I129S1Sv129X1SvJC57BL6Pcsk2tm1DfsPcsk2tm1DfsPcsk2tm1Dfs
• abnormal pancreatic islet morphology_Pcsk2<tm1Dfs>/Pcsk2<tm1Dfs>
  http://metadb.riken.jp/0005215I129S1Sv129X1SvJC57BL6Pcsk2tm1DfsPcsk2tm1DfsPcsk2tm1Dfs
• increased pancreatic delta cell number_Pcsk2<tm1Dfs>/Pcsk2<tm1Dfs>
  http://metadb.riken.jp/0009180I129S1Sv129X1SvJC57BL6Pcsk2tm1DfsPcsk2tm1DfsPcsk2tm1Dfs
• abnormal pancreatic somatostatin secretion_Pcsk2<tm1Dfs>/Pcsk2<tm1Dfs>
  http://metadb.riken.jp/0008953I129S1Sv129X1SvJC57BL6Pcsk2tm1DfsPcsk2tm1DfsPcsk2tm1Dfs
• reduced female fertility_Pcsk2<tm1Dfs>/Pcsk2<tm1Dfs>
  http://metadb.riken.jp/0001923I129S1Sv129X1SvJC57BL6Pcsk2tm1DfsPcsk2tm1DfsPcsk2tm1Dfs
• impaired glucose tolerance_Pcsk2<tm1Dfs>/Pcsk2<tm1Dfs>
  http://metadb.riken.jp/0005293I129S1Sv129X1SvJC57BL6Pcsk2tm1DfsPcsk2tm1DfsPcsk2tm1Dfs
• abnormal pancreatic alpha cell morphology_Pcsk2<tm1Dfs>/Pcsk2<tm1Dfs>
  http://metadb.riken.jp/0005216I129S1Sv129X1SvJC57BL6Pcsk2tm1DfsPcsk2tm1DfsPcsk2tm1Dfs
• decreased insulin secretion_Pcsk2<tm1Dfs>/Pcsk2<tm1Dfs>
  http://metadb.riken.jp/0003059I129S1Sv129X1SvJC57BL6Pcsk2tm1DfsPcsk2tm1DfsPcsk2tm1Dfs
• decreased circulating glucose level_Pcsk2<tm1Dfs>/Pcsk2<tm1Dfs>
  http://metadb.riken.jp/0005560I129S1Sv129X1SvJC57BL6Pcsk2tm1DfsPcsk2tm1DfsPcsk2tm1Dfs
• decreased pancreatic beta cell number_Pcsk2<tm1Dfs>/Pcsk2<tm1Dfs>
  http://metadb.riken.jp/0003339I129S1Sv129X1SvJC57BL6Pcsk2tm1DfsPcsk2tm1DfsPcsk2tm1Dfs

class

http://purl.org/net/cito/citesAsAuthority

• Pcsk2<tm1Dfs>
  http://metadb.riken.jp/db/mgi_rdf/MGI:1857445