R. Hakem, et.al., Partial rescue of Brca1 (5-6) early embryonic lethality by p53 or p21 null mutation., Nature genetics, 1997, 16

http://rdf.ncbi.nlm.nih.gov/pubmed/9207798

R. Hakem, et.al., Partial rescue of Brca1 (5-6) early embryonic lethality by p53 or p21 null mutation., Nature genetics, 1997, 16

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• failure of initiation of embryo turning_Brca1<tm1Mak>/Brca1<tm1Mak>,Trp53<tm1Tyj>/Trp53<tm1Tyj>
  http://metadb.riken.jp/0004180I129P2OlaHsd129S2SvPasBrca1tm1MakBrca1tm1MakTrp53tm1TyjTrp53tm1TyjTrp53tm1TyjBrca1tm1Mak
• decreased embryo size_Brca1<tm1Mak>/Brca1<tm1Mak>,Trp53<tm1Tyj>/Trp53<tm1Tyj>
  http://metadb.riken.jp/0001698I129P2OlaHsd129S2SvPasBrca1tm1MakBrca1tm1MakTrp53tm1TyjTrp53tm1TyjTrp53tm1TyjBrca1tm1Mak
• embryonic lethality during organogenesis, complete penetrance_Brca1<tm1Mak>/Brca1<tm1Mak>,Cdkn1a<tm1Tyj>/Cdkn1a<tm1Tyj>
  http://metadb.riken.jp/0011098I129P2OlaHsd129S2SvPasBrca1tm1MakBrca1tm1MakCdkn1atm1TyjCdkn1atm1TyjBrca1tm1MakCdkn1atm1Tyj
• embryonic lethality during organogenesis, complete penetrance_Brca1<tm1Mak>/Brca1<tm1Mak>,Trp53<tm1Tyj>/Trp53<tm1Tyj>
  http://metadb.riken.jp/0011098I129P2OlaHsd129S2SvPasBrca1tm1MakBrca1tm1MakTrp53tm1TyjTrp53tm1TyjTrp53tm1TyjBrca1tm1Mak
• abnormal allantois morphology_Brca1<tm1Mak>/Brca1<tm1Mak>,Trp53<tm1Tyj>/Trp53<tm1Tyj>
  http://metadb.riken.jp/0001726I129P2OlaHsd129S2SvPasBrca1tm1MakBrca1tm1MakTrp53tm1TyjTrp53tm1TyjTrp53tm1TyjBrca1tm1Mak
• abnormal visceral yolk sac morphology_Brca1<tm1Mak>/Brca1<tm1Mak>,Trp53<tm1Tyj>/Trp53<tm1Tyj>
  http://metadb.riken.jp/0001718I129P2OlaHsd129S2SvPasBrca1tm1MakBrca1tm1MakTrp53tm1TyjTrp53tm1TyjTrp53tm1TyjBrca1tm1Mak
• embryonic growth retardation_Brca1<tm1Mak>/Brca1<tm1Mak>,Trp53<tm1Tyj>/Trp53<tm1Tyj>
  http://metadb.riken.jp/0003984I129P2OlaHsd129S2SvPasBrca1tm1MakBrca1tm1MakTrp53tm1TyjTrp53tm1TyjTrp53tm1TyjBrca1tm1Mak