S. Akkaraju, et.al., A range of CD4 T cell tolerance: partial inactivation to organ-specific antigen allows nondestructive thyroiditis or insulitis., Immunity, 1997, 7

http://rdf.ncbi.nlm.nih.gov/pubmed/9285410

S. Akkaraju, et.al., A range of CD4 T cell tolerance: partial inactivation to organ-specific antigen allows nondestructive thyroiditis or insulitis., Immunity, 1997, 7

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(ILK3mHEL)3Ccg
  http://metadb.riken.jp/db/mgi_rdf/MGI:2385454
• Tg(TLK2mHEL)2Ccg
  http://metadb.riken.jp/db/mgi_rdf/MGI:2385453

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased double-positive T cell number_Tg(ML5sHEL)5Ccg/0,Tg(TcrHEL3A9)1Mmd/0,Tg(TLK2mHEL)2Ccg/0
  http://metadb.riken.jp/0005092IC57BL6JSfdC57BL10C57BRcdTgML5sHEL5Ccg0TgTcrHEL3A91Mmd0TgTLK2mHEL2Ccg0TgTLK2mHEL2CcgTgTcrHEL3A91MmdTgML5sHEL5Ccg
• decreased double-positive T cell number_Tg(TcrHEL3A9)1Mmd/0,Tg(TLK2mHEL)2Ccg/0
  http://metadb.riken.jp/0005092IC57BL6C57BL10C57BRcdTgTcrHEL3A91Mmd0TgTLK2mHEL2Ccg0TgTLK2mHEL2CcgTgTcrHEL3A91Mmd
• abnormal CD4-positive, alpha-beta T cell physiology_Tg(ILK3mHEL)3Ccg/0,Tg(TcrHEL3A9)1Mmd/0
  http://metadb.riken.jp/0005463IC57BL6JSfdC57BL10SgC57BRcdTgILK3mHEL3Ccg0TgTcrHEL3A91Mmd0TgILK3mHEL3CcgTgTcrHEL3A91Mmd
• decreased CD4-positive, alpha beta T cell number_Tg(ML5sHEL)5Ccg/0,Tg(TcrHEL3A9)1Mmd/0,Tg(TLK2mHEL)2Ccg/0
  http://metadb.riken.jp/0008075IC57BL6JSfdC57BL10C57BRcdTgML5sHEL5Ccg0TgTcrHEL3A91Mmd0TgTLK2mHEL2Ccg0TgTLK2mHEL2CcgTgTcrHEL3A91MmdTgML5sHEL5Ccg
• abnormal CD4-positive, alpha-beta T cell physiology_Rag2<tm1Fwa>/Rag2<tm1Fwa>,Tg(TcrHEL3A9)1Mmd/0,Tg(TLK2mHEL)2Ccg/0
  http://metadb.riken.jp/0005463I129SSvEvC57BL6Rag2tm1FwaRag2tm1FwaTgTcrHEL3A91Mmd0TgTLK2mHEL2Ccg0Rag2tm1FwaTgTLK2mHEL2CcgTgTcrHEL3A91Mmd
• abnormal CD4-positive, alpha beta T cell morphology_Tg(TcrHEL3A9)1Mmd/0
  http://metadb.riken.jp/0002432IC57BL6C57BL10C57BRcdTgTcrHEL3A91Mmd0TgTcrHEL3A91Mmd
• abnormal T cell activation_Tg(TcrHEL3A9)1Mmd/0
  http://metadb.riken.jp/0001828IC57BL6C57BL10C57BRcdTgTcrHEL3A91Mmd0TgTcrHEL3A91Mmd
• abnormal CD4-positive, alpha beta T cell morphology_Rag2<tm1Fwa>/Rag2<tm1Fwa>,Tg(TcrHEL3A9)1Mmd/0
  http://metadb.riken.jp/0002432I129SSvEvC57BL6Rag2tm1FwaRag2tm1FwaTgTcrHEL3A91Mmd0TgTcrHEL3A91MmdRag2tm1Fwa
• thyroid inflammation_Rag2<tm1Fwa>/Rag2<tm1Fwa>,Tg(TcrHEL3A9)1Mmd/0,Tg(TLK2mHEL)2Ccg/0
  http://metadb.riken.jp/0003504I129SSvEvC57BL6Rag2tm1FwaRag2tm1FwaTgTcrHEL3A91Mmd0TgTLK2mHEL2Ccg0Rag2tm1FwaTgTLK2mHEL2CcgTgTcrHEL3A91Mmd
• decreased CD4-positive, alpha beta T cell number_Tg(TcrHEL3A9)1Mmd/0,Tg(TLK2mHEL)2Ccg/0
  http://metadb.riken.jp/0008075IC57BL6C57BL10C57BRcdTgTcrHEL3A91Mmd0TgTLK2mHEL2Ccg0TgTLK2mHEL2CcgTgTcrHEL3A91Mmd
• abnormal T cell activation_Tg(TcrHEL3A9)1Mmd/0,Tg(TLK2mHEL)2Ccg/0
  http://metadb.riken.jp/0001828IC57BL6C57BL10C57BRcdTgTcrHEL3A91Mmd0TgTLK2mHEL2Ccg0TgTLK2mHEL2CcgTgTcrHEL3A91Mmd
• thyroid inflammation_Tg(TcrHEL3A9)1Mmd/0,Tg(TLK2mHEL)2Ccg/0
  http://metadb.riken.jp/0003504IC57BL6C57BL10C57BRcdTgTcrHEL3A91Mmd0TgTLK2mHEL2Ccg0TgTLK2mHEL2CcgTgTcrHEL3A91Mmd
• abnormal CD4-positive, alpha beta T cell morphology_Tg(ILK3mHEL)3Ccg/0,Tg(TcrHEL3A9)1Mmd/0
  http://metadb.riken.jp/0002432IC57BL6JSfdC57BL10SgC57BRcdTgILK3mHEL3Ccg0TgTcrHEL3A91Mmd0TgILK3mHEL3CcgTgTcrHEL3A91Mmd
• abnormal CD4-positive, alpha beta T cell morphology_Tg(ML5sHEL)5Ccg/0,Tg(TcrHEL3A9)1Mmd/0
  http://metadb.riken.jp/0002432IC57BL6C57BL10C57BRcdTgML5sHEL5Ccg0TgTcrHEL3A91Mmd0TgML5sHEL5CcgTgTcrHEL3A91Mmd
• decreased CD4-positive, alpha beta T cell number_Rag2<tm1Fwa>/Rag2<tm1Fwa>,Tg(TcrHEL3A9)1Mmd/0
  http://metadb.riken.jp/0008075I129SSvEvC57BL6Rag2tm1FwaRag2tm1FwaTgTcrHEL3A91Mmd0TgTcrHEL3A91MmdRag2tm1Fwa
• abnormal T cell proliferation_Tg(ML5sHEL)5Ccg/0,Tg(TcrHEL3A9)1Mmd/0,Tg(TLK2mHEL)2Ccg/0
  http://metadb.riken.jp/0005094IC57BL6JSfdC57BL10C57BRcdTgML5sHEL5Ccg0TgTcrHEL3A91Mmd0TgTLK2mHEL2Ccg0TgTLK2mHEL2CcgTgTcrHEL3A91MmdTgML5sHEL5Ccg
• abnormal T cell activation_Rag2<tm1Fwa>/Rag2<tm1Fwa>,Tg(TcrHEL3A9)1Mmd/0
  http://metadb.riken.jp/0001828I129SSvEvC57BL6Rag2tm1FwaRag2tm1FwaTgTcrHEL3A91Mmd0TgTcrHEL3A91MmdRag2tm1Fwa
• abnormal T cell proliferation_Tg(ILK3mHEL)3Ccg/0,Tg(TcrHEL3A9)1Mmd/0
  http://metadb.riken.jp/0005094IC57BL6JSfdC57BL10SgC57BRcdTgILK3mHEL3Ccg0TgTcrHEL3A91Mmd0TgILK3mHEL3CcgTgTcrHEL3A91Mmd
• decreased CD4-positive, alpha beta T cell number_Tg(KLK4mHEL)6Ccg/0,Tg(TcrHEL3A9)1Mmd/0
  http://metadb.riken.jp/0008075IC57BL6C57BL10C57BRcdTgKLK4mHEL6Ccg0TgTcrHEL3A91Mmd0TgTcrHEL3A91MmdTgKLK4mHEL6Ccg
• insulitis_Tg(ILK3mHEL)3Ccg/0,Tg(TcrHEL3A9)1Mmd/0
  http://metadb.riken.jp/0004031IC57BL6JSfdC57BL10SgC57BRcdTgILK3mHEL3Ccg0TgTcrHEL3A91Mmd0TgILK3mHEL3CcgTgTcrHEL3A91Mmd
• decreased double-positive T cell number_Rag2<tm1Fwa>/Rag2<tm1Fwa>,Tg(TcrHEL3A9)1Mmd/0,Tg(TLK2mHEL)2Ccg/0
  http://metadb.riken.jp/0005092I129SSvEvC57BL6Rag2tm1FwaRag2tm1FwaTgTcrHEL3A91Mmd0TgTLK2mHEL2Ccg0Rag2tm1FwaTgTLK2mHEL2CcgTgTcrHEL3A91Mmd
• abnormal T cell activation_Tg(ML5sHEL)5Ccg/0,Tg(TcrHEL3A9)1Mmd/0,Tg(TLK2mHEL)2Ccg/0
  http://metadb.riken.jp/0001828IC57BL6JSfdC57BL10C57BRcdTgML5sHEL5Ccg0TgTcrHEL3A91Mmd0TgTLK2mHEL2Ccg0TgTLK2mHEL2CcgTgTcrHEL3A91MmdTgML5sHEL5Ccg
• abnormal T cell activation_Tg(ML5sHEL)5Ccg/0,Tg(TcrHEL3A9)1Mmd/0
  http://metadb.riken.jp/0001828IC57BL6C57BL10C57BRcdTgML5sHEL5Ccg0TgTcrHEL3A91Mmd0TgML5sHEL5CcgTgTcrHEL3A91Mmd
• abnormal T cell proliferation_Tg(TcrHEL3A9)1Mmd/0
  http://metadb.riken.jp/0005094IC57BL6C57BL10C57BRcdTgTcrHEL3A91Mmd0TgTcrHEL3A91Mmd
• abnormal CD4-positive, alpha-beta T cell physiology_Tg(TcrHEL3A9)1Mmd/0,Tg(TLK2mHEL)2Ccg/0
  http://metadb.riken.jp/0005463IC57BL6C57BL10C57BRcdTgTcrHEL3A91Mmd0TgTLK2mHEL2Ccg0TgTLK2mHEL2CcgTgTcrHEL3A91Mmd
• thyroid inflammation_Tg(ML5sHEL)5Ccg/0,Tg(TcrHEL3A9)1Mmd/0,Tg(TLK2mHEL)2Ccg/0
  http://metadb.riken.jp/0003504IC57BL6JSfdC57BL10C57BRcdTgML5sHEL5Ccg0TgTcrHEL3A91Mmd0TgTLK2mHEL2Ccg0TgTLK2mHEL2CcgTgTcrHEL3A91MmdTgML5sHEL5Ccg
• decreased double-positive T cell number_Tg(KLK4mHEL)6Ccg/0,Tg(TcrHEL3A9)1Mmd/0
  http://metadb.riken.jp/0005092IC57BL6C57BL10C57BRcdTgKLK4mHEL6Ccg0TgTcrHEL3A91Mmd0TgTcrHEL3A91MmdTgKLK4mHEL6Ccg
• abnormal CD4-positive, alpha-beta T cell physiology_Tg(ML5sHEL)5Ccg/0,Tg(TcrHEL3A9)1Mmd/0,Tg(TLK2mHEL)2Ccg/0
  http://metadb.riken.jp/0005463IC57BL6JSfdC57BL10C57BRcdTgML5sHEL5Ccg0TgTcrHEL3A91Mmd0TgTLK2mHEL2Ccg0TgTLK2mHEL2CcgTgTcrHEL3A91MmdTgML5sHEL5Ccg
• abnormal CD4-positive, alpha-beta T cell physiology_Tg(ML5sHEL)5Ccg/0,Tg(TcrHEL3A9)1Mmd/0
  http://metadb.riken.jp/0005463IC57BL6C57BL10C57BRcdTgML5sHEL5Ccg0TgTcrHEL3A91Mmd0TgML5sHEL5CcgTgTcrHEL3A91Mmd
• abnormal T cell activation_Rag2<tm1Fwa>/Rag2<tm1Fwa>,Tg(TcrHEL3A9)1Mmd/0,Tg(TLK2mHEL)2Ccg/0
  http://metadb.riken.jp/0001828I129SSvEvC57BL6Rag2tm1FwaRag2tm1FwaTgTcrHEL3A91Mmd0TgTLK2mHEL2Ccg0Rag2tm1FwaTgTLK2mHEL2CcgTgTcrHEL3A91Mmd
• decreased CD4-positive, alpha beta T cell number_Tg(TcrHEL3A9)1Mmd/0
  http://metadb.riken.jp/0008075IC57BL6C57BL10C57BRcdTgTcrHEL3A91Mmd0TgTcrHEL3A91Mmd
• abnormal thymus cell ratio_Rag2<tm1Fwa>/Rag2<tm1Fwa>,Tg(TcrHEL3A9)1Mmd/0
  http://metadb.riken.jp/0008827I129SSvEvC57BL6Rag2tm1FwaRag2tm1FwaTgTcrHEL3A91Mmd0TgTcrHEL3A91MmdRag2tm1Fwa
• decreased double-positive T cell number_Tg(ML5sHEL)5Ccg/0,Tg(TcrHEL3A9)1Mmd/0
  http://metadb.riken.jp/0005092IC57BL6C57BL10C57BRcdTgML5sHEL5Ccg0TgTcrHEL3A91Mmd0TgML5sHEL5CcgTgTcrHEL3A91Mmd
• abnormal T cell proliferation_Rag2<tm1Fwa>/Rag2<tm1Fwa>,Tg(TcrHEL3A9)1Mmd/0,Tg(TLK2mHEL)2Ccg/0
  http://metadb.riken.jp/0005094I129SSvEvC57BL6Rag2tm1FwaRag2tm1FwaTgTcrHEL3A91Mmd0TgTLK2mHEL2Ccg0Rag2tm1FwaTgTLK2mHEL2CcgTgTcrHEL3A91Mmd
• abnormal CD4-positive, alpha beta T cell morphology_Rag2<tm1Fwa>/Rag2<tm1Fwa>,Tg(TcrHEL3A9)1Mmd/0,Tg(TLK2mHEL)2Ccg/0
  http://metadb.riken.jp/0002432I129SSvEvC57BL6Rag2tm1FwaRag2tm1FwaTgTcrHEL3A91Mmd0TgTLK2mHEL2Ccg0Rag2tm1FwaTgTLK2mHEL2CcgTgTcrHEL3A91Mmd
• abnormal T cell proliferation_Rag2<tm1Fwa>/Rag2<tm1Fwa>,Tg(TcrHEL3A9)1Mmd/0
  http://metadb.riken.jp/0005094I129SSvEvC57BL6Rag2tm1FwaRag2tm1FwaTgTcrHEL3A91Mmd0TgTcrHEL3A91MmdRag2tm1Fwa
• abnormal thymus cell ratio_Tg(TcrHEL3A9)1Mmd/0
  http://metadb.riken.jp/0008827IC57BL6C57BL10C57BRcdTgTcrHEL3A91Mmd0TgTcrHEL3A91Mmd
• abnormal CD4-positive, alpha beta T cell morphology_Tg(TcrHEL3A9)1Mmd/0,Tg(TLK2mHEL)2Ccg/0
  http://metadb.riken.jp/0002432IC57BL6C57BL10C57BRcdTgTcrHEL3A91Mmd0TgTLK2mHEL2Ccg0TgTLK2mHEL2CcgTgTcrHEL3A91Mmd
• decreased CD4-positive, alpha beta T cell number_Tg(ILK3mHEL)3Ccg/0,Tg(TcrHEL3A9)1Mmd/0
  http://metadb.riken.jp/0008075IC57BL6JSfdC57BL10SgC57BRcdTgILK3mHEL3Ccg0TgTcrHEL3A91Mmd0TgILK3mHEL3CcgTgTcrHEL3A91Mmd
• abnormal double-positive T cell morphology_Tg(TcrHEL3A9)1Mmd/0
  http://metadb.riken.jp/0002408IC57BL6C57BL10C57BRcdTgTcrHEL3A91Mmd0TgTcrHEL3A91Mmd
• decreased CD4-positive, alpha beta T cell number_Tg(ML5sHEL)5Ccg/0,Tg(TcrHEL3A9)1Mmd/0
  http://metadb.riken.jp/0008075IC57BL6C57BL10C57BRcdTgML5sHEL5Ccg0TgTcrHEL3A91Mmd0TgML5sHEL5CcgTgTcrHEL3A91Mmd
• abnormal CD4-positive, alpha beta T cell morphology_Tg(ML5sHEL)5Ccg/0,Tg(TcrHEL3A9)1Mmd/0,Tg(TLK2mHEL)2Ccg/0
  http://metadb.riken.jp/0002432IC57BL6JSfdC57BL10C57BRcdTgML5sHEL5Ccg0TgTcrHEL3A91Mmd0TgTLK2mHEL2Ccg0TgTLK2mHEL2CcgTgTcrHEL3A91MmdTgML5sHEL5Ccg
• abnormal T cell proliferation_Tg(ML5sHEL)5Ccg/0,Tg(TcrHEL3A9)1Mmd/0
  http://metadb.riken.jp/0005094IC57BL6C57BL10C57BRcdTgML5sHEL5Ccg0TgTcrHEL3A91Mmd0TgML5sHEL5CcgTgTcrHEL3A91Mmd
• abnormal T cell proliferation_Tg(TcrHEL3A9)1Mmd/0,Tg(TLK2mHEL)2Ccg/0
  http://metadb.riken.jp/0005094IC57BL6C57BL10C57BRcdTgTcrHEL3A91Mmd0TgTLK2mHEL2Ccg0TgTLK2mHEL2CcgTgTcrHEL3A91Mmd
• decreased CD4-positive, alpha beta T cell number_Rag2<tm1Fwa>/Rag2<tm1Fwa>,Tg(TcrHEL3A9)1Mmd/0,Tg(TLK2mHEL)2Ccg/0
  http://metadb.riken.jp/0008075I129SSvEvC57BL6Rag2tm1FwaRag2tm1FwaTgTcrHEL3A91Mmd0TgTLK2mHEL2Ccg0Rag2tm1FwaTgTLK2mHEL2CcgTgTcrHEL3A91Mmd
• abnormal double-positive T cell morphology_Rag2<tm1Fwa>/Rag2<tm1Fwa>,Tg(TcrHEL3A9)1Mmd/0
  http://metadb.riken.jp/0002408I129SSvEvC57BL6Rag2tm1FwaRag2tm1FwaTgTcrHEL3A91Mmd0TgTcrHEL3A91MmdRag2tm1Fwa
• abnormal T cell activation_Tg(ILK3mHEL)3Ccg/0,Tg(TcrHEL3A9)1Mmd/0
  http://metadb.riken.jp/0001828IC57BL6JSfdC57BL10SgC57BRcdTgILK3mHEL3Ccg0TgTcrHEL3A91Mmd0TgILK3mHEL3CcgTgTcrHEL3A91Mmd

class

http://purl.org/net/cito/citesAsAuthority

• Tg(ILK3mHEL)3Ccg
  http://metadb.riken.jp/db/mgi_rdf/MGI:2385454
• Tg(TLK2mHEL)2Ccg
  http://metadb.riken.jp/db/mgi_rdf/MGI:2385453