D. Riethmacher, et.al., Severe neuropathies in mice with targeted mutations in the ErbB3 receptor., Nature, 1997, 389

http://rdf.ncbi.nlm.nih.gov/pubmed/9338783

D. Riethmacher, et.al., Severe neuropathies in mice with targeted mutations in the ErbB3 receptor., Nature, 1997, 389

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Erbb3<tm2Cbm>
  http://metadb.riken.jp/db/mgi_rdf/MGI:1929598
• Erbb3<tm1Cbm>
  http://metadb.riken.jp/db/mgi_rdf/MGI:1929072

class

http://purl.org/net/cito/citesAsAuthority

• Erbb3<tm2Cbm>
  http://metadb.riken.jp/db/mgi_rdf/MGI:1929598
• Erbb3<tm1Cbm>
  http://metadb.riken.jp/db/mgi_rdf/MGI:1929072

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• motor neuron degeneration_Erbb3<tm2Cbm>/Erbb3<tm2Cbm>
  http://metadb.riken.jp/0000938E129P2OlaHsdorI129P2OlaHsdC57BL6Erbb3tm2CbmErbb3tm2CbmErbb3tm2Cbm
• no spontaneous movement_Erbb3<tm1Cbm>/Erbb3<tm1Cbm>
  http://metadb.riken.jp/0001404E129P2OlaHsdorI129P2OlaHsdC57BL6Erbb3tm1CbmErbb3tm1CbmErbb3tm1Cbm
• increased neuron apoptosis_Erbb3<tm1Cbm>/Erbb3<tm1Cbm>
  http://metadb.riken.jp/0003203E129P2OlaHsdorI129P2OlaHsdC57BL6Erbb3tm1CbmErbb3tm1CbmErbb3tm1Cbm
• abnormal PNS glial cell morphology_Erbb3<tm2Cbm>/Erbb3<tm2Cbm>
  http://metadb.riken.jp/0001105E129P2OlaHsdorI129P2OlaHsdC57BL6Erbb3tm2CbmErbb3tm2CbmErbb3tm2Cbm
• embryonic lethality during organogenesis, incomplete penetrance_Erbb3<tm1Cbm>/Erbb3<tm1Cbm>
  http://metadb.riken.jp/0011108E129P2OlaHsdorI129P2OlaHsdC57BL6Erbb3tm1CbmErbb3tm1CbmErbb3tm1Cbm
• no spontaneous movement_Erbb3<tm2Cbm>/Erbb3<tm2Cbm>
  http://metadb.riken.jp/0001404E129P2OlaHsdorI129P2OlaHsdC57BL6Erbb3tm2CbmErbb3tm2CbmErbb3tm2Cbm
• decreased body weight_Erbb3<tm1Cbm>/Erbb3<tm1Cbm>
  http://metadb.riken.jp/0001262E129P2OlaHsdorI129P2OlaHsdC57BL6Erbb3tm1CbmErbb3tm1CbmErbb3tm1Cbm
• increased neuron apoptosis_Erbb3<tm2Cbm>/Erbb3<tm2Cbm>
  http://metadb.riken.jp/0003203E129P2OlaHsdorI129P2OlaHsdC57BL6Erbb3tm2CbmErbb3tm2CbmErbb3tm2Cbm
• abnormal cranial nerve morphology_Erbb3<tm2Cbm>/Erbb3<tm2Cbm>
  http://metadb.riken.jp/0001056E129P2OlaHsdorI129P2OlaHsdC57BL6Erbb3tm2CbmErbb3tm2CbmErbb3tm2Cbm
• cyanosis_Erbb3<tm1Cbm>/Erbb3<tm1Cbm>
  http://metadb.riken.jp/0001575E129P2OlaHsdorI129P2OlaHsdC57BL6Erbb3tm1CbmErbb3tm1CbmErbb3tm1Cbm
• neuron degeneration_Erbb3<tm1Cbm>/Erbb3<tm1Cbm>
  http://metadb.riken.jp/0003224E129P2OlaHsdorI129P2OlaHsdC57BL6Erbb3tm1CbmErbb3tm1CbmErbb3tm1Cbm
• respiratory failure_Erbb3<tm2Cbm>/Erbb3<tm2Cbm>
  http://metadb.riken.jp/0001953E129P2OlaHsdorI129P2OlaHsdC57BL6Erbb3tm2CbmErbb3tm2CbmErbb3tm2Cbm
• abnormal PNS glial cell morphology_Erbb3<tm1Cbm>/Erbb3<tm1Cbm>
  http://metadb.riken.jp/0001105E129P2OlaHsdorI129P2OlaHsdC57BL6Erbb3tm1CbmErbb3tm1CbmErbb3tm1Cbm
• respiratory failure_Erbb3<tm1Cbm>/Erbb3<tm1Cbm>
  http://metadb.riken.jp/0001953E129P2OlaHsdorI129P2OlaHsdC57BL6Erbb3tm1CbmErbb3tm1CbmErbb3tm1Cbm
• neuron degeneration_Erbb3<tm2Cbm>/Erbb3<tm2Cbm>
  http://metadb.riken.jp/0003224E129P2OlaHsdorI129P2OlaHsdC57BL6Erbb3tm2CbmErbb3tm2CbmErbb3tm2Cbm
• perinatal lethality, complete penetrance_Erbb3<tm1Cbm>/Erbb3<tm1Cbm>
  http://metadb.riken.jp/0011089E129P2OlaHsdorI129P2OlaHsdC57BL6Erbb3tm1CbmErbb3tm1CbmErbb3tm1Cbm
• unresponsive to tactile stimuli_Erbb3<tm2Cbm>/Erbb3<tm2Cbm>
  http://metadb.riken.jp/0001491E129P2OlaHsdorI129P2OlaHsdC57BL6Erbb3tm2CbmErbb3tm2CbmErbb3tm2Cbm
• motor neuron degeneration_Erbb3<tm1Cbm>/Erbb3<tm1Cbm>
  http://metadb.riken.jp/0000938E129P2OlaHsdorI129P2OlaHsdC57BL6Erbb3tm1CbmErbb3tm1CbmErbb3tm1Cbm
• abnormal dorsal root ganglion morphology_Erbb3<tm1Cbm>/Erbb3<tm1Cbm>
  http://metadb.riken.jp/0000961E129P2OlaHsdorI129P2OlaHsdC57BL6Erbb3tm1CbmErbb3tm1CbmErbb3tm1Cbm
• decreased body weight_Erbb3<tm2Cbm>/Erbb3<tm2Cbm>
  http://metadb.riken.jp/0001262E129P2OlaHsdorI129P2OlaHsdC57BL6Erbb3tm2CbmErbb3tm2CbmErbb3tm2Cbm
• absent Schwann cell precursors_Erbb3<tm1Cbm>/Erbb3<tm1Cbm>
  http://metadb.riken.jp/0001109E129P2OlaHsdorI129P2OlaHsdC57BL6Erbb3tm1CbmErbb3tm1CbmErbb3tm1Cbm
• abnormal dorsal root ganglion morphology_Erbb3<tm2Cbm>/Erbb3<tm2Cbm>
  http://metadb.riken.jp/0000961E129P2OlaHsdorI129P2OlaHsdC57BL6Erbb3tm2CbmErbb3tm2CbmErbb3tm2Cbm
• abnormal cranial ganglia morphology_Erbb3<tm2Cbm>/Erbb3<tm2Cbm>
  http://metadb.riken.jp/0001081E129P2OlaHsdorI129P2OlaHsdC57BL6Erbb3tm2CbmErbb3tm2CbmErbb3tm2Cbm
• small dorsal root ganglion_Erbb3<tm2Cbm>/Erbb3<tm2Cbm>
  http://metadb.riken.jp/0000964E129P2OlaHsdorI129P2OlaHsdC57BL6Erbb3tm2CbmErbb3tm2CbmErbb3tm2Cbm
• embryonic lethality during organogenesis, incomplete penetrance_Erbb3<tm2Cbm>/Erbb3<tm2Cbm>
  http://metadb.riken.jp/0011108E129P2OlaHsdorI129P2OlaHsdC57BL6Erbb3tm2CbmErbb3tm2CbmErbb3tm2Cbm
• cyanosis_Erbb3<tm2Cbm>/Erbb3<tm2Cbm>
  http://metadb.riken.jp/0001575E129P2OlaHsdorI129P2OlaHsdC57BL6Erbb3tm2CbmErbb3tm2CbmErbb3tm2Cbm
• small dorsal root ganglion_Erbb3<tm1Cbm>/Erbb3<tm1Cbm>
  http://metadb.riken.jp/0000964E129P2OlaHsdorI129P2OlaHsdC57BL6Erbb3tm1CbmErbb3tm1CbmErbb3tm1Cbm
• absent Schwann cell precursors_Erbb3<tm2Cbm>/Erbb3<tm2Cbm>
  http://metadb.riken.jp/0001109E129P2OlaHsdorI129P2OlaHsdC57BL6Erbb3tm2CbmErbb3tm2CbmErbb3tm2Cbm
• abnormal cranial nerve morphology_Erbb3<tm1Cbm>/Erbb3<tm1Cbm>
  http://metadb.riken.jp/0001056E129P2OlaHsdorI129P2OlaHsdC57BL6Erbb3tm1CbmErbb3tm1CbmErbb3tm1Cbm
• perinatal lethality, complete penetrance_Erbb3<tm2Cbm>/Erbb3<tm2Cbm>
  http://metadb.riken.jp/0011089E129P2OlaHsdorI129P2OlaHsdC57BL6Erbb3tm2CbmErbb3tm2CbmErbb3tm2Cbm
• unresponsive to tactile stimuli_Erbb3<tm1Cbm>/Erbb3<tm1Cbm>
  http://metadb.riken.jp/0001491E129P2OlaHsdorI129P2OlaHsdC57BL6Erbb3tm1CbmErbb3tm1CbmErbb3tm1Cbm
• abnormal cranial ganglia morphology_Erbb3<tm1Cbm>/Erbb3<tm1Cbm>
  http://metadb.riken.jp/0001081E129P2OlaHsdorI129P2OlaHsdC57BL6Erbb3tm1CbmErbb3tm1CbmErbb3tm1Cbm