F. Connor, et.al., Tumorigenesis and a DNA repair defect in mice with a truncating Brca2 mutation., Nature genetics, 1997, 17

http://rdf.ncbi.nlm.nih.gov/pubmed/9398843

F. Connor, et.al., Tumorigenesis and a DNA repair defect in mice with a truncating Brca2 mutation., Nature genetics, 1997, 17

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Brca2<tm1Cbl>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2177226

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• postnatal lethality, incomplete penetrance_Brca2<tm1Cbl>/Brca2<tm1Cbl>
  http://metadb.riken.jp/0011086EI129S2SvPasC57BL10orI129S2SvPasC57BL6DBA2Brca2tm1CblBrca2tm1CblBrca2tm1Cbl
• male infertility_Brca2<tm1Cbl>/Brca2<tm1Cbl>
  http://metadb.riken.jp/0001925EI129S2SvPasC57BL10orI129S2SvPasC57BL6DBA2Brca2tm1CblBrca2tm1CblBrca2tm1Cbl
• abnormal sternum morphology_Brca2<tm1Cbl>/Brca2<tm1Cbl>
  http://metadb.riken.jp/0000157EI129S2SvPasC57BL10orI129S2SvPasC57BL6DBA2Brca2tm1CblBrca2tm1CblBrca2tm1Cbl
• abnormal epidermal layer morphology_Brca2<tm1Cbl>/Brca2<tm1Cbl>
  http://metadb.riken.jp/0001216EI129S2SvPasC57BL10orI129S2SvPasC57BL6DBA2Brca2tm1CblBrca2tm1CblBrca2tm1Cbl
• abnormal epidermis stratum basale morphology_Brca2<tm1Cbl>/Brca2<tm1Cbl>
  http://metadb.riken.jp/0001231EI129S2SvPasC57BL10orI129S2SvPasC57BL6DBA2Brca2tm1CblBrca2tm1CblBrca2tm1Cbl
• absent ovarian follicles_Brca2<tm1Cbl>/Brca2<tm1Cbl>
  http://metadb.riken.jp/0002777EI129S2SvPasC57BL10orI129S2SvPasC57BL6DBA2Brca2tm1CblBrca2tm1CblBrca2tm1Cbl
• ovary degeneration_Brca2<tm1Cbl>/Brca2<tm1Cbl>
  http://metadb.riken.jp/0013236EI129S2SvPasC57BL10orI129S2SvPasC57BL6DBA2Brca2tm1CblBrca2tm1CblBrca2tm1Cbl
• decreased birth weight_Brca2<tm1Cbl>/Brca2<tm1Cbl>
  http://metadb.riken.jp/0009674EI129S2SvPasC57BL10orI129S2SvPasC57BL6DBA2Brca2tm1CblBrca2tm1CblBrca2tm1Cbl
• decreased fetal weight_Brca2<tm1Cbl>/Brca2<tm1Cbl>
  http://metadb.riken.jp/0009431EI129S2SvPasC57BL10orI129S2SvPasC57BL6DBA2Brca2tm1CblBrca2tm1CblBrca2tm1Cbl
• abnormal double-strand DNA break repair_Brca2<tm1Cbl>/Brca2<tm1Cbl>
  http://metadb.riken.jp/0010948EI129S2SvPasC57BL10orI129S2SvPasC57BL6DBA2Brca2tm1CblBrca2tm1CblBrca2tm1Cbl
• increased T cell derived lymphoma incidence_Brca2<tm1Cbl>/Brca2<tm1Cbl>
  http://metadb.riken.jp/0002024EI129S2SvPasC57BL10orI129S2SvPasC57BL6DBA2Brca2tm1CblBrca2tm1CblBrca2tm1Cbl
• decreased body weight_Brca2<tm1Cbl>/Brca2<tm1Cbl>
  http://metadb.riken.jp/0001262EI129S2SvPasC57BL10orI129S2SvPasC57BL6DBA2Brca2tm1CblBrca2tm1CblBrca2tm1Cbl
• azoospermia_Brca2<tm1Cbl>/Brca2<tm1Cbl>
  http://metadb.riken.jp/0005159EI129S2SvPasC57BL10orI129S2SvPasC57BL6DBA2Brca2tm1CblBrca2tm1CblBrca2tm1Cbl
• kinked tail_Brca2<tm1Cbl>/Brca2<tm1Cbl>
  http://metadb.riken.jp/0000585EI129S2SvPasC57BL10orI129S2SvPasC57BL6DBA2Brca2tm1CblBrca2tm1CblBrca2tm1Cbl
• abnormal skin morphology_Brca2<tm1Cbl>/Brca2<tm1Cbl>
  http://metadb.riken.jp/0002060EI129S2SvPasC57BL10orI129S2SvPasC57BL6DBA2Brca2tm1CblBrca2tm1CblBrca2tm1Cbl
• small ovary_Brca2<tm1Cbl>/Brca2<tm1Cbl>
  http://metadb.riken.jp/0001127EI129S2SvPasC57BL10orI129S2SvPasC57BL6DBA2Brca2tm1CblBrca2tm1CblBrca2tm1Cbl
• abnormal epidermis stratum spinosum morphology_Brca2<tm1Cbl>/Brca2<tm1Cbl>
  http://metadb.riken.jp/0001236EI129S2SvPasC57BL10orI129S2SvPasC57BL6DBA2Brca2tm1CblBrca2tm1CblBrca2tm1Cbl
• small testis_Brca2<tm1Cbl>/Brca2<tm1Cbl>
  http://metadb.riken.jp/0001147EI129S2SvPasC57BL10orI129S2SvPasC57BL6DBA2Brca2tm1CblBrca2tm1CblBrca2tm1Cbl
• premature death_Brca2<tm1Cbl>/Brca2<tm1Cbl>
  http://metadb.riken.jp/0002083EI129S2SvPasC57BL10orI129S2SvPasC57BL6DBA2Brca2tm1CblBrca2tm1CblBrca2tm1Cbl
• fetal growth retardation_Brca2<tm1Cbl>/Brca2<tm1Cbl>
  http://metadb.riken.jp/0004201EI129S2SvPasC57BL10orI129S2SvPasC57BL6DBA2Brca2tm1CblBrca2tm1CblBrca2tm1Cbl
• abnormal rib morphology_Brca2<tm1Cbl>/Brca2<tm1Cbl>
  http://metadb.riken.jp/0000150EI129S2SvPasC57BL10orI129S2SvPasC57BL6DBA2Brca2tm1CblBrca2tm1CblBrca2tm1Cbl
• absent epidermis stratum corneum_Brca2<tm1Cbl>/Brca2<tm1Cbl>
  http://metadb.riken.jp/0001241EI129S2SvPasC57BL10orI129S2SvPasC57BL6DBA2Brca2tm1CblBrca2tm1CblBrca2tm1Cbl
• decreased fibroblast proliferation_Brca2<tm1Cbl>/Brca2<tm1Cbl>
  http://metadb.riken.jp/0011704EI129S2SvPasC57BL10orI129S2SvPasC57BL6DBA2Brca2tm1CblBrca2tm1CblBrca2tm1Cbl

class

http://purl.org/net/cito/citesAsAuthority

• Brca2<tm1Cbl>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2177226