X. Yang, et.al., The tumor suppressor SMAD4/DPC4 is essential for epiblast proliferation and mesoderm induction in mice., Proceedings of the National Academy of Sciences of the United States of America, 1998, 95

http://rdf.ncbi.nlm.nih.gov/pubmed/9520423

X. Yang, et.al., The tumor suppressor SMAD4/DPC4 is essential for epiblast proliferation and mesoderm induction in mice., Proceedings of the National Academy of Sciences of the United States of America, 1998, 95

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Smad4<tm1Cxd>
  http://metadb.riken.jp/db/mgi_rdf/MGI:1857698

class

http://purl.org/net/cito/citesAsAuthority

• Smad4<tm1Cxd>
  http://metadb.riken.jp/db/mgi_rdf/MGI:1857698

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• embryonic growth arrest_Smad4<tm1Cxd>/Smad4<tm1Cxd>
  http://metadb.riken.jp/0001730I129S6SvEvTacSmad4tm1CxdSmad4tm1CxdSmad4tm1Cxd
• decreased inner cell mass proliferation_Smad4<tm1Cxd>/Smad4<tm1Cxd>
  http://metadb.riken.jp/0012113I129S6SvEvTacSmad4tm1CxdSmad4tm1CxdSmad4tm1Cxd
• no abnormal phenotype detected_Smad4<tm1Cxd>/Smad4<+>
  http://metadb.riken.jp/0002169I129S6SvEvTacSmad4tm1CxdSmad4Smad4tm1CxdSmad4
• abnormal embryonic tissue morphology_Smad4<tm1Cxd>/Smad4<tm1Cxd>
  http://metadb.riken.jp/0002085I129S6SvEvTacSmad4tm1CxdSmad4tm1CxdSmad4tm1Cxd
• failure of primitive streak formation_Smad4<tm1Cxd>/Smad4<tm1Cxd>
  http://metadb.riken.jp/0001693I129S6SvEvTacSmad4tm1CxdSmad4tm1CxdSmad4tm1Cxd
• abnormal embryonic-extraembryonic boundary morphology_Smad4<tm1Cxd>/Smad4<tm1Cxd>
  http://metadb.riken.jp/0003890I129S6SvEvTacSmad4tm1CxdSmad4tm1CxdSmad4tm1Cxd
• absent egg cylinders_Smad4<tm1Cxd>/Smad4<tm1Cxd>
  http://metadb.riken.jp/0001694I129S6SvEvTacSmad4tm1CxdSmad4tm1CxdSmad4tm1Cxd
• abnormal extraembryonic tissue morphology_Smad4<tm1Cxd>/Smad4<tm1Cxd>
  http://metadb.riken.jp/0002086I129S6SvEvTacSmad4tm1CxdSmad4tm1CxdSmad4tm1Cxd
• abnormal endoderm development_Smad4<tm1Cxd>/Smad4<tm1Cxd>
  http://metadb.riken.jp/0001685I129S6SvEvTacSmad4tm1CxdSmad4tm1CxdSmad4tm1Cxd
• small ectoplacental cone_Smad4<tm1Cxd>/Smad4<tm1Cxd>
  http://metadb.riken.jp/0002584I129S6SvEvTacSmad4tm1CxdSmad4tm1CxdSmad4tm1Cxd
• decreased cell proliferation_Smad4<tm1Cxd>/Smad4<tm1Cxd>
  http://metadb.riken.jp/0000352I129S6SvEvTacSmad4tm1CxdSmad4tm1CxdSmad4tm1Cxd
• increased Reichert's membrane thickness_Smad4<tm1Cxd>/Smad4<tm1Cxd>
  http://metadb.riken.jp/0012095I129S6SvEvTacSmad4tm1CxdSmad4tm1CxdSmad4tm1Cxd
• decreased embryo size_Smad4<tm1Cxd>/Smad4<tm1Cxd>
  http://metadb.riken.jp/0001698I129S6SvEvTacSmad4tm1CxdSmad4tm1CxdSmad4tm1Cxd
• absent mesoderm_Smad4<tm1Cxd>/Smad4<tm1Cxd>
  http://metadb.riken.jp/0001683I129S6SvEvTacSmad4tm1CxdSmad4tm1CxdSmad4tm1Cxd
• decreased embryonic epiblast cell proliferation_Smad4<tm1Cxd>/Smad4<tm1Cxd>
  http://metadb.riken.jp/0011192I129S6SvEvTacSmad4tm1CxdSmad4tm1CxdSmad4tm1Cxd
• embryonic lethality between somite formation and embryo turning, incomplete penetrance_Smad4<tm1Cxd>/Smad4<tm1Cxd>
  http://metadb.riken.jp/0011107I129S6SvEvTacSmad4tm1CxdSmad4tm1CxdSmad4tm1Cxd
• embryonic lethality between implantation and somite formation, incomplete penetrance_Smad4<tm1Cxd>/Smad4<tm1Cxd>
  http://metadb.riken.jp/0011106I129S6SvEvTacSmad4tm1CxdSmad4tm1CxdSmad4tm1Cxd