L. Sussel, et.al., Mice lacking the homeodomain transcription factor Nkx2.2 have diabetes due to arrested differentiation of pancreatic beta cells., Development (Cambridge, England), 1998, 125

http://rdf.ncbi.nlm.nih.gov/pubmed/9584121

L. Sussel, et.al., Mice lacking the homeodomain transcription factor Nkx2.2 have diabetes due to arrested differentiation of pancreatic beta cells., Development (Cambridge, England), 1998, 125

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Nkx2-2<tm1Jlr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:1932100

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• absent pancreatic beta cells_Nkx2-2<tm1Jlr>/Nkx2-2<tm1Jlr>
  http://metadb.riken.jp/0009174I129X1SvJNkx22tm1JlrNkx22tm1JlrNkx22tm1Jlr
• decreased PP cell number_Nkx2-2<tm1Jlr>/Nkx2-2<tm1Jlr>
  http://metadb.riken.jp/0009186I129X1SvJNkx22tm1JlrNkx22tm1JlrNkx22tm1Jlr
• hyperglycemia_Nkx2-2<tm1Jlr>/Nkx2-2<tm1Jlr>
  http://metadb.riken.jp/0001559I129X1SvJNkx22tm1JlrNkx22tm1JlrNkx22tm1Jlr
• abnormal pancreatic beta cell differentiation_Nkx2-2<tm1Jlr>/Nkx2-2<tm1Jlr>
  http://metadb.riken.jp/0009175I129X1SvJNkx22tm1JlrNkx22tm1JlrNkx22tm1Jlr
• decreased pancreatic alpha cell number_Nkx2-2<tm1Jlr>/Nkx2-2<tm1Jlr>
  http://metadb.riken.jp/0009177I129X1SvJNkx22tm1JlrNkx22tm1JlrNkx22tm1Jlr
• postnatal growth retardation_Nkx2-2<tm1Jlr>/Nkx2-2<tm1Jlr>
  http://metadb.riken.jp/0001732I129X1SvJNkx22tm1JlrNkx22tm1JlrNkx22tm1Jlr
• decreased insulin secretion_Nkx2-2<tm1Jlr>/Nkx2-2<tm1Jlr>
  http://metadb.riken.jp/0003059I129X1SvJNkx22tm1JlrNkx22tm1JlrNkx22tm1Jlr
• abnormal pancreatic islet morphology_Nkx2-2<tm1Jlr>/Nkx2-2<tm1Jlr>
  http://metadb.riken.jp/0005215I129X1SvJNkx22tm1JlrNkx22tm1JlrNkx22tm1Jlr
• decreased glucagon secretion_Nkx2-2<tm1Jlr>/Nkx2-2<tm1Jlr>
  http://metadb.riken.jp/0002711I129X1SvJNkx22tm1JlrNkx22tm1JlrNkx22tm1Jlr
• postnatal lethality, complete penetrance_Nkx2-2<tm1Jlr>/Nkx2-2<tm1Jlr>
  http://metadb.riken.jp/0011085I129X1SvJNkx22tm1JlrNkx22tm1JlrNkx22tm1Jlr

class

http://purl.org/net/cito/citesAsAuthority

• Nkx2-2<tm1Jlr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:1932100

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD21574
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD21574