T P. Yao, et.al., Gene dosage-dependent embryonic development and proliferation defects in mice lacking the transcriptional integrator p300., Cell, 1998, 93

http://rdf.ncbi.nlm.nih.gov/pubmed/9590171

T P. Yao, et.al., Gene dosage-dependent embryonic development and proliferation defects in mice lacking the transcriptional integrator p300., Cell, 1998, 93

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Ep300<tm1Dli>
  http://metadb.riken.jp/db/mgi_rdf/MGI:1858020

class

http://purl.org/net/cito/citesAsAuthority

• Ep300<tm1Dli>
  http://metadb.riken.jp/db/mgi_rdf/MGI:1858020

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• absent trabeculae carneae_Ep300<tm1Dli>/Ep300<tm1Dli>
  http://metadb.riken.jp/0000296E129S4SvJaeorI129S4SvJaeC57BL6Ep300tm1DliEp300tm1DliEp300tm1Dli
• exencephaly_Crebbp<tm1Dli>/Crebbp<+>,Ep300<tm1Dli>/Ep300<+>
  http://metadb.riken.jp/0000914I129S4SvJae129S6SvEvTacC57BL6Crebbptm1DliCrebbpEp300tm1DliEp300Ep300Crebbptm1DliEp300tm1DliCrebbp
• decreased embryo size_Crebbp<tm1Dli>/Crebbp<+>,Ep300<tm1Dli>/Ep300<+>
  http://metadb.riken.jp/0001698I129S4SvJae129S6SvEvTacC57BL6Crebbptm1DliCrebbpEp300tm1DliEp300Ep300Crebbptm1DliEp300tm1DliCrebbp
• decreased embryo size_Ep300<tm1Dli>/Ep300<tm1Dli>
  http://metadb.riken.jp/0001698E129S4SvJaeorI129S4SvJaeC57BL6Ep300tm1DliEp300tm1DliEp300tm1Dli
• kinked neural tube_Ep300<tm1Dli>/Ep300<tm1Dli>
  http://metadb.riken.jp/0003400I129S4SvJaeC57BL6Ep300tm1DliEp300tm1DliEp300tm1Dli
• early cellular replicative senescence_Ep300<tm1Dli>/Ep300<tm1Dli>
  http://metadb.riken.jp/0008008E129S4SvJaeorI129S4SvJaeC57BL6Ep300tm1DliEp300tm1DliEp300tm1Dli
• abnormal vitelline vasculature morphology_Ep300<tm1Dli>/Ep300<tm1Dli>
  http://metadb.riken.jp/0003229E129S4SvJaeorI129S4SvJaeC57BL6Ep300tm1DliEp300tm1DliEp300tm1Dli
• enlarged heart_Ep300<tm1Dli>/Ep300<tm1Dli>
  http://metadb.riken.jp/0000274E129S4SvJaeorI129S4SvJaeC57BL6Ep300tm1DliEp300tm1DliEp300tm1Dli
• exencephaly_Ep300<tm1Dli>/Ep300<+>
  http://metadb.riken.jp/0000914E129S4SvJaeorI129S4SvJaeC57BL6Ep300tm1DliEp300Ep300tm1DliEp300
• decreased fibroblast proliferation_Ep300<tm1Dli>/Ep300<tm1Dli>
  http://metadb.riken.jp/0011704E129S4SvJaeorI129S4SvJaeC57BL6Ep300tm1DliEp300tm1DliEp300tm1Dli
• abnormal head morphology_Ep300<tm1Dli>/Ep300<tm1Dli>
  http://metadb.riken.jp/0000432I129S4SvJaeC57BL6Ep300tm1DliEp300tm1DliEp300tm1Dli
• incomplete somite formation_Ep300<tm1Dli>/Ep300<tm1Dli>
  http://metadb.riken.jp/0001689E129S4SvJaeorI129S4SvJaeC57BL6Ep300tm1DliEp300tm1DliEp300tm1Dli
• pericardial effusion_Ep300<tm1Dli>/Ep300<tm1Dli>
  http://metadb.riken.jp/0005312E129S4SvJaeorI129S4SvJaeC57BL6Ep300tm1DliEp300tm1DliEp300tm1Dli
• embryonic lethality during organogenesis, complete penetrance_Ep300<tm1Dli>/Ep300<tm1Dli>
  http://metadb.riken.jp/0011098I129S4SvJaeC57BL6Ep300tm1DliEp300tm1DliEp300tm1Dli
• open neural tube_Ep300<tm1Dli>/Ep300<+>
  http://metadb.riken.jp/0000929E129S4SvJaeorI129S4SvJaeC57BL6Ep300tm1DliEp300Ep300tm1DliEp300
• open neural tube_Ep300<tm1Dli>/Ep300<tm1Dli>
  http://metadb.riken.jp/0000929I129S4SvJaeC57BL6Ep300tm1DliEp300tm1DliEp300tm1Dli
• exencephaly_Ep300<tm1Dli>/Ep300<tm1Dli>
  http://metadb.riken.jp/0000914I129S4SvJaeC57BL6Ep300tm1DliEp300tm1DliEp300tm1Dli
• decreased embryo size_Ep300<tm1Dli>/Ep300<tm1Dli>
  http://metadb.riken.jp/0001698I129S4SvJaeC57BL6Ep300tm1DliEp300tm1DliEp300tm1Dli
• open neural tube_Crebbp<tm1Dli>/Crebbp<+>,Ep300<tm1Dli>/Ep300<+>
  http://metadb.riken.jp/0000929I129S4SvJae129S6SvEvTacC57BL6Crebbptm1DliCrebbpEp300tm1DliEp300Ep300Crebbptm1DliEp300tm1DliCrebbp
• microphthalmia_Ep300<tm1Dli>/Ep300<tm1Dli>
  http://metadb.riken.jp/0001297I129S4SvJaeC57BL6Ep300tm1DliEp300tm1DliEp300tm1Dli
• decreased embryo size_Ep300<tm1Dli>/Ep300<+>
  http://metadb.riken.jp/0001698E129S4SvJaeorI129S4SvJaeC57BL6Ep300tm1DliEp300Ep300tm1DliEp300
• embryonic lethality during organogenesis, incomplete penetrance_Ep300<tm1Dli>/Ep300<+>
  http://metadb.riken.jp/0011108E129S4SvJaeorI129S4SvJaeC57BL6Ep300tm1DliEp300Ep300tm1DliEp300
• abnormal cell physiology_Ep300<tm1Dli>/Ep300<tm1Dli>
  http://metadb.riken.jp/0005621E129S4SvJaeorI129S4SvJaeC57BL6Ep300tm1DliEp300tm1DliEp300tm1Dli
• prenatal lethality, complete penetrance_Crebbp<tm1Dli>/Crebbp<+>,Ep300<tm1Dli>/Ep300<+>
  http://metadb.riken.jp/0011091I129S4SvJae129S6SvEvTacC57BL6Crebbptm1DliCrebbpEp300tm1DliEp300Ep300Crebbptm1DliEp300tm1DliCrebbp
• embryonic lethality during organogenesis, incomplete penetrance_Ep300<tm1Dli>/Ep300<tm1Dli>
  http://metadb.riken.jp/0011108E129S4SvJaeorI129S4SvJaeC57BL6Ep300tm1DliEp300tm1DliEp300tm1Dli
• decreased cardiac muscle contractility_Ep300<tm1Dli>/Ep300<tm1Dli>
  http://metadb.riken.jp/0005140E129S4SvJaeorI129S4SvJaeC57BL6Ep300tm1DliEp300tm1DliEp300tm1Dli
• embryonic growth retardation_Ep300<tm1Dli>/Ep300<tm1Dli>
  http://metadb.riken.jp/0003984E129S4SvJaeorI129S4SvJaeC57BL6Ep300tm1DliEp300tm1DliEp300tm1Dli
• incomplete embryo turning_Ep300<tm1Dli>/Ep300<tm1Dli>
  http://metadb.riken.jp/0001701E129S4SvJaeorI129S4SvJaeC57BL6Ep300tm1DliEp300tm1DliEp300tm1Dli
• embryonic growth arrest_Ep300<tm1Dli>/Ep300<tm1Dli>
  http://metadb.riken.jp/0001730I129S4SvJaeC57BL6Ep300tm1DliEp300tm1DliEp300tm1Dli

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD11637
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD11637
• CD01650
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD01650