F. Cecconi, et.al., Apaf1 (CED-4 homolog) regulates programmed cell death in mammalian development., Cell, 1998, 94

http://rdf.ncbi.nlm.nih.gov/pubmed/9753320

F. Cecconi, et.al., Apaf1 (CED-4 homolog) regulates programmed cell death in mammalian development., Cell, 1998, 94

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• lethality throughout fetal growth and development, complete penetrance_Apaf1<Gt(IRESBetageo)XIX18Pgr>/Apaf1<Gt(IRESBetageo)XIX18Pgr>
  http://metadb.riken.jp/0011099I129S1Sv129X1SvJNMRIApaf1GtIRESBetageoXIX18PgrApaf1GtIRESBetageoXIX18PgrApaf1GtIRESBetageoXIX18Pgr
• persistence of hyaloid vascular system_Apaf1<Gt(IRESBetageo)XIX18Pgr>/Apaf1<Gt(IRESBetageo)XIX18Pgr>
  http://metadb.riken.jp/0001289I129S1Sv129X1SvJNMRIApaf1GtIRESBetageoXIX18PgrApaf1GtIRESBetageoXIX18PgrApaf1GtIRESBetageoXIX18Pgr
• small embryonic telencephalon_Apaf1<Gt(IRESBetageo)XIX18Pgr>/Apaf1<Gt(IRESBetageo)XIX18Pgr>
  http://metadb.riken.jp/0000936I129S1Sv129X1SvJNMRIApaf1GtIRESBetageoXIX18PgrApaf1GtIRESBetageoXIX18PgrApaf1GtIRESBetageoXIX18Pgr
• midbrain hyperplasia_Apaf1<Gt(IRESBetageo)XIX18Pgr>/Apaf1<Gt(IRESBetageo)XIX18Pgr>
  http://metadb.riken.jp/0000898I129S1Sv129X1SvJNMRIApaf1GtIRESBetageoXIX18PgrApaf1GtIRESBetageoXIX18PgrApaf1GtIRESBetageoXIX18Pgr
• hypothalamus hyperplasia_Apaf1<Gt(IRESBetageo)XIX18Pgr>/Apaf1<Gt(IRESBetageo)XIX18Pgr>
  http://metadb.riken.jp/0000839I129S1Sv129X1SvJNMRIApaf1GtIRESBetageoXIX18PgrApaf1GtIRESBetageoXIX18PgrApaf1GtIRESBetageoXIX18Pgr
• impaired ossification of basisphenoid bone_Apaf1<Gt(IRESBetageo)XIX18Pgr>/Apaf1<Gt(IRESBetageo)XIX18Pgr>
  http://metadb.riken.jp/0000105I129S1Sv129X1SvJNMRIApaf1GtIRESBetageoXIX18PgrApaf1GtIRESBetageoXIX18PgrApaf1GtIRESBetageoXIX18Pgr
• persistence of medial edge epithelium during palatal shelf fusion_Apaf1<Gt(IRESBetageo)XIX18Pgr>/Apaf1<Gt(IRESBetageo)XIX18Pgr>
  http://metadb.riken.jp/0009889I129S1Sv129X1SvJNMRIApaf1GtIRESBetageoXIX18PgrApaf1GtIRESBetageoXIX18PgrApaf1GtIRESBetageoXIX18Pgr
• hydroencephaly_Apaf1<Gt(IRESBetageo)XIX18Pgr>/Apaf1<Gt(IRESBetageo)XIX18Pgr>
  http://metadb.riken.jp/0001891I129S1Sv129X1SvJNMRIApaf1GtIRESBetageoXIX18PgrApaf1GtIRESBetageoXIX18PgrApaf1GtIRESBetageoXIX18Pgr
• interdigital webbing_Apaf1<Gt(IRESBetageo)XIX18Pgr>/Apaf1<Gt(IRESBetageo)XIX18Pgr>
  http://metadb.riken.jp/0000571I129S1Sv129X1SvJNMRIApaf1GtIRESBetageoXIX18PgrApaf1GtIRESBetageoXIX18PgrApaf1GtIRESBetageoXIX18Pgr
• decreased fibroblast apoptosis_Apaf1<Gt(IRESBetageo)XIX18Pgr>/Apaf1<Gt(IRESBetageo)XIX18Pgr>
  http://metadb.riken.jp/0013502I129S1Sv129X1SvJNMRIApaf1GtIRESBetageoXIX18PgrApaf1GtIRESBetageoXIX18PgrApaf1GtIRESBetageoXIX18Pgr
• midline facial cleft_Apaf1<Gt(IRESBetageo)XIX18Pgr>/Apaf1<Gt(IRESBetageo)XIX18Pgr>
  http://metadb.riken.jp/0000108I129S1Sv129X1SvJNMRIApaf1GtIRESBetageoXIX18PgrApaf1GtIRESBetageoXIX18PgrApaf1GtIRESBetageoXIX18Pgr
• abnormal lens polarity_Apaf1<Gt(IRESBetageo)XIX18Pgr>/Apaf1<Gt(IRESBetageo)XIX18Pgr>
  http://metadb.riken.jp/0001308I129S1Sv129X1SvJNMRIApaf1GtIRESBetageoXIX18PgrApaf1GtIRESBetageoXIX18PgrApaf1GtIRESBetageoXIX18Pgr
• exencephaly_Apaf1<Gt(IRESBetageo)XIX18Pgr>/Apaf1<Gt(IRESBetageo)XIX18Pgr>
  http://metadb.riken.jp/0000914I129S1Sv129X1SvJNMRIApaf1GtIRESBetageoXIX18PgrApaf1GtIRESBetageoXIX18PgrApaf1GtIRESBetageoXIX18Pgr
• abnormal brain morphology_Apaf1<Gt(IRESBetageo)XIX18Pgr>/Apaf1<Gt(IRESBetageo)XIX18Pgr>
  http://metadb.riken.jp/0002152I129S1Sv129X1SvJNMRIApaf1GtIRESBetageoXIX18PgrApaf1GtIRESBetageoXIX18PgrApaf1GtIRESBetageoXIX18Pgr
• absent vomer bone_Apaf1<Gt(IRESBetageo)XIX18Pgr>/Apaf1<Gt(IRESBetageo)XIX18Pgr>
  http://metadb.riken.jp/0000099I129S1Sv129X1SvJNMRIApaf1GtIRESBetageoXIX18PgrApaf1GtIRESBetageoXIX18PgrApaf1GtIRESBetageoXIX18Pgr
• abnormal embryonic tissue morphology_Apaf1<Gt(IRESBetageo)XIX18Pgr>/Apaf1<Gt(IRESBetageo)XIX18Pgr>
  http://metadb.riken.jp/0002085I129S1Sv129X1SvJNMRIApaf1GtIRESBetageoXIX18PgrApaf1GtIRESBetageoXIX18PgrApaf1GtIRESBetageoXIX18Pgr
• choroid plexus hyperplasia_Apaf1<Gt(IRESBetageo)XIX18Pgr>/Apaf1<Gt(IRESBetageo)XIX18Pgr>
  http://metadb.riken.jp/0000821I129S1Sv129X1SvJNMRIApaf1GtIRESBetageoXIX18PgrApaf1GtIRESBetageoXIX18PgrApaf1GtIRESBetageoXIX18Pgr
• abnormal craniofacial bone morphology_Apaf1<Gt(IRESBetageo)XIX18Pgr>/Apaf1<Gt(IRESBetageo)XIX18Pgr>
  http://metadb.riken.jp/0002116I129S1Sv129X1SvJNMRIApaf1GtIRESBetageoXIX18PgrApaf1GtIRESBetageoXIX18PgrApaf1GtIRESBetageoXIX18Pgr
• abnormal embryonic neuroepithelial layer differentiation_Apaf1<Gt(IRESBetageo)XIX18Pgr>/Apaf1<Gt(IRESBetageo)XIX18Pgr>
  http://metadb.riken.jp/0000786I129S1Sv129X1SvJNMRIApaf1GtIRESBetageoXIX18PgrApaf1GtIRESBetageoXIX18PgrApaf1GtIRESBetageoXIX18Pgr
• small lens_Apaf1<Gt(IRESBetageo)XIX18Pgr>/Apaf1<Gt(IRESBetageo)XIX18Pgr>
  http://metadb.riken.jp/0001306I129S1Sv129X1SvJNMRIApaf1GtIRESBetageoXIX18PgrApaf1GtIRESBetageoXIX18PgrApaf1GtIRESBetageoXIX18Pgr
• diencephalon hyperplasia_Apaf1<Gt(IRESBetageo)XIX18Pgr>/Apaf1<Gt(IRESBetageo)XIX18Pgr>
  http://metadb.riken.jp/0000831I129S1Sv129X1SvJNMRIApaf1GtIRESBetageoXIX18PgrApaf1GtIRESBetageoXIX18PgrApaf1GtIRESBetageoXIX18Pgr
• absent ethmoidal bone_Apaf1<Gt(IRESBetageo)XIX18Pgr>/Apaf1<Gt(IRESBetageo)XIX18Pgr>
  http://metadb.riken.jp/0000101I129S1Sv129X1SvJNMRIApaf1GtIRESBetageoXIX18PgrApaf1GtIRESBetageoXIX18PgrApaf1GtIRESBetageoXIX18Pgr
• retina hyperplasia_Apaf1<Gt(IRESBetageo)XIX18Pgr>/Apaf1<Gt(IRESBetageo)XIX18Pgr>
  http://metadb.riken.jp/0001329I129S1Sv129X1SvJNMRIApaf1GtIRESBetageoXIX18PgrApaf1GtIRESBetageoXIX18PgrApaf1GtIRESBetageoXIX18Pgr
• abnormal brain development_Apaf1<Gt(IRESBetageo)XIX18Pgr>/Apaf1<Gt(IRESBetageo)XIX18Pgr>
  http://metadb.riken.jp/0000913I129S1Sv129X1SvJNMRIApaf1GtIRESBetageoXIX18PgrApaf1GtIRESBetageoXIX18PgrApaf1GtIRESBetageoXIX18Pgr
• abnormal cortical marginal zone morphology_Apaf1<Gt(IRESBetageo)XIX18Pgr>/Apaf1<Gt(IRESBetageo)XIX18Pgr>
  http://metadb.riken.jp/0000792I129S1Sv129X1SvJNMRIApaf1GtIRESBetageoXIX18PgrApaf1GtIRESBetageoXIX18PgrApaf1GtIRESBetageoXIX18Pgr
• absent neurocranium_Apaf1<Gt(IRESBetageo)XIX18Pgr>/Apaf1<Gt(IRESBetageo)XIX18Pgr>
  http://metadb.riken.jp/0000075I129S1Sv129X1SvJNMRIApaf1GtIRESBetageoXIX18PgrApaf1GtIRESBetageoXIX18PgrApaf1GtIRESBetageoXIX18Pgr
• abnormal folding of telencephalic vesicles_Apaf1<Gt(IRESBetageo)XIX18Pgr>/Apaf1<Gt(IRESBetageo)XIX18Pgr>
  http://metadb.riken.jp/0000935I129S1Sv129X1SvJNMRIApaf1GtIRESBetageoXIX18PgrApaf1GtIRESBetageoXIX18PgrApaf1GtIRESBetageoXIX18Pgr

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD03102
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD03102