G E. Taccioli, et.al., Targeted disruption of the catalytic subunit of the DNA-PK gene in mice confers severe combined immunodeficiency and radiosensitivity., Immunity, 1998, 9

http://rdf.ncbi.nlm.nih.gov/pubmed/9768755

G E. Taccioli, et.al., Targeted disruption of the catalytic subunit of the DNA-PK gene in mice confers severe combined immunodeficiency and radiosensitivity., Immunity, 1998, 9

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Prkdc<tm1Get>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2383951

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal T cell receptor beta chain V(D)J recombination_Prkdc<tm1Get>/Prkdc<tm1Get>
  http://metadb.riken.jp/0008758I129S4SvJaeBlackSwissPrkdctm1GetPrkdctm1GetPrkdctm1Get
• increased cellular sensitivity to gamma-irradiation_Prkdc<tm1Get>/Prkdc<tm1Get>
  http://metadb.riken.jp/0002007I129S4SvJaeBlackSwissPrkdctm1GetPrkdctm1GetPrkdctm1Get
• arrested T cell differentiation_Prkdc<tm1Get>/Prkdc<tm1Get>
  http://metadb.riken.jp/0001825I129S4SvJaeBlackSwissPrkdctm1GetPrkdctm1GetPrkdctm1Get
• increased NK cell number_Prkdc<tm1Get>/Prkdc<tm1Get>
  http://metadb.riken.jp/0008044I129S4SvJaeBlackSwissPrkdctm1GetPrkdctm1GetPrkdctm1Get
• abnormal T cell receptor alpha chain V-J recombination_Prkdc<tm1Get>/Prkdc<tm1Get>
  http://metadb.riken.jp/0008756I129S4SvJaeBlackSwissPrkdctm1GetPrkdctm1GetPrkdctm1Get
• increased double-negative T cell number_Prkdc<tm1Get>/Prkdc<tm1Get>
  http://metadb.riken.jp/0005090I129S4SvJaeBlackSwissPrkdctm1GetPrkdctm1GetPrkdctm1Get
• decreased spleen white pulp amount_Prkdc<tm1Get>/Prkdc<tm1Get>
  http://metadb.riken.jp/0008479I129S4SvJaeBlackSwissPrkdctm1GetPrkdctm1GetPrkdctm1Get
• abnormal B cell differentiation_Prkdc<tm1Get>/Prkdc<tm1Get>
  http://metadb.riken.jp/0002144I129S4SvJaeBlackSwissPrkdctm1GetPrkdctm1GetPrkdctm1Get
• abnormal thymus corticomedullary boundary morphology_Prkdc<tm1Get>/Prkdc<tm1Get>
  http://metadb.riken.jp/0009543I129S4SvJaeBlackSwissPrkdctm1GetPrkdctm1GetPrkdctm1Get
• abnormal immunoglobulin light chain V-J recombination_Prkdc<tm1Get>/Prkdc<tm1Get>
  http://metadb.riken.jp/0008761I129S4SvJaeBlackSwissPrkdctm1GetPrkdctm1GetPrkdctm1Get
• thymus hypoplasia_Prkdc<tm1Get>/Prkdc<tm1Get>
  http://metadb.riken.jp/0001823I129S4SvJaeBlackSwissPrkdctm1GetPrkdctm1GetPrkdctm1Get
• spleen hypoplasia_Prkdc<tm1Get>/Prkdc<tm1Get>
  http://metadb.riken.jp/0000694I129S4SvJaeBlackSwissPrkdctm1GetPrkdctm1GetPrkdctm1Get
• arrested B cell differentiation_Prkdc<tm1Get>/Prkdc<tm1Get>
  http://metadb.riken.jp/0001802I129S4SvJaeBlackSwissPrkdctm1GetPrkdctm1GetPrkdctm1Get
• increased double-positive T cell number_Prkdc<tm1Get>/Prkdc<tm1Get>
  http://metadb.riken.jp/0005091I129S4SvJaeBlackSwissPrkdctm1GetPrkdctm1GetPrkdctm1Get
• abnormal T cell receptor delta chain V(D)J recombination_Prkdc<tm1Get>/Prkdc<tm1Get>
  http://metadb.riken.jp/0008759I129S4SvJaeBlackSwissPrkdctm1GetPrkdctm1GetPrkdctm1Get
• abnormal immunoglobulin heavy chain V(D)J recombination_Prkdc<tm1Get>/Prkdc<tm1Get>
  http://metadb.riken.jp/0008760I129S4SvJaeBlackSwissPrkdctm1GetPrkdctm1GetPrkdctm1Get
• small lymph nodes_Prkdc<tm1Get>/Prkdc<tm1Get>
  http://metadb.riken.jp/0002217I129S4SvJaeBlackSwissPrkdctm1GetPrkdctm1GetPrkdctm1Get
• abnormal T cell number_Prkdc<tm1Get>/Prkdc<tm1Get>
  http://metadb.riken.jp/0006387I129S4SvJaeBlackSwissPrkdctm1GetPrkdctm1GetPrkdctm1Get
• decreased IgM level_Prkdc<tm1Get>/Prkdc<tm1Get>
  http://metadb.riken.jp/0001806I129S4SvJaeBlackSwissPrkdctm1GetPrkdctm1GetPrkdctm1Get
• abnormal T cell differentiation_Prkdc<tm1Get>/Prkdc<tm1Get>
  http://metadb.riken.jp/0002145I129S4SvJaeBlackSwissPrkdctm1GetPrkdctm1GetPrkdctm1Get
• decreased single-positive T cell number_Prkdc<tm1Get>/Prkdc<tm1Get>
  http://metadb.riken.jp/0008083I129S4SvJaeBlackSwissPrkdctm1GetPrkdctm1GetPrkdctm1Get

class

http://purl.org/net/cito/citesAsAuthority

• Prkdc<tm1Get>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2383951