I. Shimomura, et.al., Insulin resistance and diabetes mellitus in transgenic mice expressing nuclear SREBP-1c in adipose tissue: model for congenital generalized lipodystrophy., Genes & development, 1998, 12

http://rdf.ncbi.nlm.nih.gov/pubmed/9784493

I. Shimomura, et.al., Insulin resistance and diabetes mellitus in transgenic mice expressing nuclear SREBP-1c in adipose tissue: model for congenital generalized lipodystrophy., Genes & development, 1998, 12

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(aP2-SREBF1c)9884Reh
  http://metadb.riken.jp/db/mgi_rdf/MGI:3028848

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• distended abdomen_Tg(aP2-SREBF1c)9884Reh/0
  http://metadb.riken.jp/0001270IC57BL6JSJLTgaP2SREBF1c9884Reh0TgaP2SREBF1c9884Reh
• hepatic steatosis_Tg(aP2-SREBF1c)9884Reh/0
  http://metadb.riken.jp/0002628IC57BL6JSJLTgaP2SREBF1c9884Reh0TgaP2SREBF1c9884Reh
• increased liver weight_Tg(aP2-SREBF1c)9884Reh/0
  http://metadb.riken.jp/0002981IC57BL6JSJLTgaP2SREBF1c9884Reh0TgaP2SREBF1c9884Reh
• increased circulating insulin level_Tg(aP2-SREBF1c)9884Reh/0
  http://metadb.riken.jp/0002079IC57BL6JSJLTgaP2SREBF1c9884Reh0TgaP2SREBF1c9884Reh
• enlarged spleen_Tg(aP2-SREBF1c)9884Reh/0
  http://metadb.riken.jp/0000691IC57BL6JSJLTgaP2SREBF1c9884Reh0TgaP2SREBF1c9884Reh
• increased liver triglyceride level_Tg(aP2-SREBF1c)9884Reh/0
  http://metadb.riken.jp/0009355IC57BL6JSJLTgaP2SREBF1c9884Reh0TgaP2SREBF1c9884Reh
• abnormal abdominal lymph node morphology_Tg(aP2-SREBF1c)9884Reh/0
  http://metadb.riken.jp/0009625IC57BL6JSJLTgaP2SREBF1c9884Reh0TgaP2SREBF1c9884Reh
• increased brown adipose tissue amount_Tg(aP2-SREBF1c)9884Reh/0
  http://metadb.riken.jp/0000005IC57BL6JSJLTgaP2SREBF1c9884Reh0TgaP2SREBF1c9884Reh
• abnormal brown adipose tissue morphology_Tg(aP2-SREBF1c)9884Reh/0
  http://metadb.riken.jp/0002971IC57BL6JSJLTgaP2SREBF1c9884Reh0TgaP2SREBF1c9884Reh
• decreased epididymal fat pad weight_Tg(aP2-SREBF1c)9884Reh/0
  http://metadb.riken.jp/0009289IC57BL6JSJLTgaP2SREBF1c9884Reh0TgaP2SREBF1c9884Reh
• hyperglycemia_Tg(aP2-SREBF1c)9884Reh/0
  http://metadb.riken.jp/0001559IC57BL6JSJLTgaP2SREBF1c9884Reh0TgaP2SREBF1c9884Reh
• decreased body size_Tg(aP2-SREBF1c)9884Reh/0
  http://metadb.riken.jp/0001265IC57BL6JSJLTgaP2SREBF1c9884Reh0TgaP2SREBF1c9884Reh
• increased brown fat cell lipid droplet size_Tg(aP2-SREBF1c)9884Reh/0
  http://metadb.riken.jp/0009124IC57BL6JSJLTgaP2SREBF1c9884Reh0TgaP2SREBF1c9884Reh
• abnormal hepatocyte morphology_Tg(aP2-SREBF1c)9884Reh/0
  http://metadb.riken.jp/0000607IC57BL6JSJLTgaP2SREBF1c9884Reh0TgaP2SREBF1c9884Reh
• pale liver_Tg(aP2-SREBF1c)9884Reh/0
  http://metadb.riken.jp/0000603IC57BL6JSJLTgaP2SREBF1c9884Reh0TgaP2SREBF1c9884Reh
• abnormal brown fat cell morphology_Tg(aP2-SREBF1c)9884Reh/0
  http://metadb.riken.jp/0009116IC57BL6JSJLTgaP2SREBF1c9884Reh0TgaP2SREBF1c9884Reh
• increased circulating triglyceride level_Tg(aP2-SREBF1c)9884Reh/0
  http://metadb.riken.jp/0001552IC57BL6JSJLTgaP2SREBF1c9884Reh0TgaP2SREBF1c9884Reh
• abnormal epididymal fat pad morphology_Tg(aP2-SREBF1c)9884Reh/0
  http://metadb.riken.jp/0006319IC57BL6JSJLTgaP2SREBF1c9884Reh0TgaP2SREBF1c9884Reh
• abnormal interscapular fat pad morphology_Tg(aP2-SREBF1c)9884Reh/0
  http://metadb.riken.jp/0006320IC57BL6JSJLTgaP2SREBF1c9884Reh0TgaP2SREBF1c9884Reh
• abnormal white adipose tissue morphology_Tg(aP2-SREBF1c)9884Reh/0
  http://metadb.riken.jp/0002970IC57BL6JSJLTgaP2SREBF1c9884Reh0TgaP2SREBF1c9884Reh
• increased brown fat cell size_Tg(aP2-SREBF1c)9884Reh/0
  http://metadb.riken.jp/0009119IC57BL6JSJLTgaP2SREBF1c9884Reh0TgaP2SREBF1c9884Reh
• abnormal liver lobule morphology_Tg(aP2-SREBF1c)9884Reh/0
  http://metadb.riken.jp/0008987IC57BL6JSJLTgaP2SREBF1c9884Reh0TgaP2SREBF1c9884Reh
• increased interscapular fat pad weight_Tg(aP2-SREBF1c)9884Reh/0
  http://metadb.riken.jp/0009294IC57BL6JSJLTgaP2SREBF1c9884Reh0TgaP2SREBF1c9884Reh
• postnatal lethality_Tg(aP2-SREBF1c)9884Reh/0
  http://metadb.riken.jp/0002082IC57BL6JSJLTgaP2SREBF1c9884Reh0TgaP2SREBF1c9884Reh
• insulin resistance_Tg(aP2-SREBF1c)9884Reh/0
  http://metadb.riken.jp/0005331IC57BL6JSJLTgaP2SREBF1c9884Reh0TgaP2SREBF1c9884Reh
• increased circulating cholesterol level_Tg(aP2-SREBF1c)9884Reh/0
  http://metadb.riken.jp/0005178IC57BL6JSJLTgaP2SREBF1c9884Reh0TgaP2SREBF1c9884Reh
• decreased white adipose tissue amount_Tg(aP2-SREBF1c)9884Reh/0
  http://metadb.riken.jp/0001783IC57BL6JSJLTgaP2SREBF1c9884Reh0TgaP2SREBF1c9884Reh
• enlarged pancreas_Tg(aP2-SREBF1c)9884Reh/0
  http://metadb.riken.jp/0003450IC57BL6JSJLTgaP2SREBF1c9884Reh0TgaP2SREBF1c9884Reh
• enlarged liver_Tg(aP2-SREBF1c)9884Reh/0
  http://metadb.riken.jp/0000599IC57BL6JSJLTgaP2SREBF1c9884Reh0TgaP2SREBF1c9884Reh

class

http://purl.org/net/cito/citesAsAuthority

• Tg(aP2-SREBF1c)9884Reh
  http://metadb.riken.jp/db/mgi_rdf/MGI:3028848