M C. Naski, et.al., Repression of hedgehog signaling and BMP4 expression in growth plate cartilage by fibroblast growth factor receptor 3., Development (Cambridge, England), 1998, 125

http://rdf.ncbi.nlm.nih.gov/pubmed/9811582

M C. Naski, et.al., Repression of hedgehog signaling and BMP4 expression in growth plate cartilage by fibroblast growth factor receptor 3., Development (Cambridge, England), 1998, 125

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(Col2a1-Fgfr3/GH)ADor
  http://metadb.riken.jp/db/mgi_rdf/MGI:2181545
• Tg(Col2a1-Fgfr3/GH)BDor
  http://metadb.riken.jp/db/mgi_rdf/MGI:2181547

class

http://purl.org/net/cito/citesAsAuthority

• Tg(Col2a1-Fgfr3/GH)ADor
  http://metadb.riken.jp/db/mgi_rdf/MGI:2181545
• Tg(Col2a1-Fgfr3/GH)BDor
  http://metadb.riken.jp/db/mgi_rdf/MGI:2181547

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased long bone epiphyseal plate size_Tg(Col2a1-Fgfr3/GH)BDor/0
  http://metadb.riken.jp/0006396FVBNTgCol2a1Fgfr3GHBDorTgCol2a1Fgfr3GHBDor0TgCol2a1Fgfr3GHBDor
• axial skeleton hypoplasia_Tg(Col2a1-Fgfr3/GH)BDor/0
  http://metadb.riken.jp/0000071FVBNTgCol2a1Fgfr3GHBDorTgCol2a1Fgfr3GHBDor0TgCol2a1Fgfr3GHBDor
• abnormal limb bone morphology_Tg(Col2a1-Fgfr3/GH)BDor/0
  http://metadb.riken.jp/0002115FVBNTgCol2a1Fgfr3GHBDorTgCol2a1Fgfr3GHBDor0TgCol2a1Fgfr3GHBDor
• delayed endochondral bone ossification_Tg(Col2a1-Fgfr3/GH)BDor/0
  http://metadb.riken.jp/0003419FVBNTgCol2a1Fgfr3GHBDorTgCol2a1Fgfr3GHBDor0TgCol2a1Fgfr3GHBDor
• domed cranium_Tg(Col2a1-Fgfr3/GH)BDor/0
  http://metadb.riken.jp/0000440FVBNTgCol2a1Fgfr3GHBDorTgCol2a1Fgfr3GHBDor0TgCol2a1Fgfr3GHBDor
• proportional dwarf_Tg(Col2a1-Fgfr3/GH)BDor/0
  http://metadb.riken.jp/0008974FVBNTgCol2a1Fgfr3GHBDorTgCol2a1Fgfr3GHBDor0TgCol2a1Fgfr3GHBDor
• proportional dwarf_Tg(Col2a1-Fgfr3/GH)ADor/Tg(Col2a1-Fgfr3/GH)ADor
  http://metadb.riken.jp/0008974FVBNTgCol2a1Fgfr3GHADorTgCol2a1Fgfr3GHADorTgCol2a1Fgfr3GHADorTgCol2a1Fgfr3GHADor
• abnormal perichondrium morphology_Tg(Col2a1-Fgfr3/GH)BDor/0
  http://metadb.riken.jp/0006322FVBNTgCol2a1Fgfr3GHBDorTgCol2a1Fgfr3GHBDor0TgCol2a1Fgfr3GHBDor
• abnormal craniofacial bone morphology_Tg(Col2a1-Fgfr3/GH)BDor/0
  http://metadb.riken.jp/0002116FVBNTgCol2a1Fgfr3GHBDorTgCol2a1Fgfr3GHBDor0TgCol2a1Fgfr3GHBDor
• kyphosis_Tg(Col2a1-Fgfr3/GH)BDor/0
  http://metadb.riken.jp/0000160FVBNTgCol2a1Fgfr3GHBDorTgCol2a1Fgfr3GHBDor0TgCol2a1Fgfr3GHBDor
• decreased width of hypertrophic chondrocyte zone_Tg(Col2a1-Fgfr3/GH)BDor/0
  http://metadb.riken.jp/0003409FVBNTgCol2a1Fgfr3GHBDorTgCol2a1Fgfr3GHBDor0TgCol2a1Fgfr3GHBDor
• absent vertebral spinous process_Tg(Col2a1-Fgfr3/GH)BDor/0
  http://metadb.riken.jp/0004606FVBNTgCol2a1Fgfr3GHBDorTgCol2a1Fgfr3GHBDor0TgCol2a1Fgfr3GHBDor
• abnormal vertebrae development_Tg(Col2a1-Fgfr3/GH)BDor/0
  http://metadb.riken.jp/0005225FVBNTgCol2a1Fgfr3GHBDorTgCol2a1Fgfr3GHBDor0TgCol2a1Fgfr3GHBDor
• abnormal chondrocyte physiology_Tg(Col2a1-Fgfr3/GH)BDor/0
  http://metadb.riken.jp/0009780FVBNTgCol2a1Fgfr3GHBDorTgCol2a1Fgfr3GHBDor0TgCol2a1Fgfr3GHBDor
• abnormal appendicular skeleton morphology_Tg(Col2a1-Fgfr3/GH)BDor/0
  http://metadb.riken.jp/0009250FVBNTgCol2a1Fgfr3GHBDorTgCol2a1Fgfr3GHBDor0TgCol2a1Fgfr3GHBDor
• decreased length of long bones_Tg(Col2a1-Fgfr3/GH)BDor/0
  http://metadb.riken.jp/0004686FVBNTgCol2a1Fgfr3GHBDorTgCol2a1Fgfr3GHBDor0TgCol2a1Fgfr3GHBDor
• abnormal long bone epiphyseal plate proliferative zone_Tg(Col2a1-Fgfr3/GH)BDor/0
  http://metadb.riken.jp/0003662FVBNTgCol2a1Fgfr3GHBDorTgCol2a1Fgfr3GHBDor0TgCol2a1Fgfr3GHBDor
• abnormal vertebrae morphology_Tg(Col2a1-Fgfr3/GH)BDor/0
  http://metadb.riken.jp/0000137FVBNTgCol2a1Fgfr3GHBDorTgCol2a1Fgfr3GHBDor0TgCol2a1Fgfr3GHBDor
• abnormal osteoclast differentiation_Tg(Col2a1-Fgfr3/GH)BDor/0
  http://metadb.riken.jp/0008396FVBNTgCol2a1Fgfr3GHBDorTgCol2a1Fgfr3GHBDor0TgCol2a1Fgfr3GHBDor
• abnormal long bone epiphyseal ossification zone morphology_Tg(Col2a1-Fgfr3/GH)BDor/0
  http://metadb.riken.jp/0006399FVBNTgCol2a1Fgfr3GHBDorTgCol2a1Fgfr3GHBDor0TgCol2a1Fgfr3GHBDor