S X. Shen, et.al., A targeted disruption of the murine Brca1 gene causes gamma-irradiation hypersensitivity and genetic instability., Oncogene, 1998, 17

http://rdf.ncbi.nlm.nih.gov/pubmed/9872327

S X. Shen, et.al., A targeted disruption of the murine Brca1 gene causes gamma-irradiation hypersensitivity and genetic instability., Oncogene, 1998, 17

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Brca1<tm1Cxd>
  http://metadb.riken.jp/db/mgi_rdf/MGI:1930612

class

http://purl.org/net/cito/citesAsAuthority

• Brca1<tm1Cxd>
  http://metadb.riken.jp/db/mgi_rdf/MGI:1930612

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased embryo size_Brca1<tm1Cxd>/Brca1<tm1Cxd>
  http://metadb.riken.jp/0001698E129S6SvEvTacBrca1tm1CxdorI129S6SvEvBrdBlackSwissorI129S6SvEvBrdC57BL6Brca1tm1CxdBrca1tm1CxdBrca1tm1Cxd
• increased cellular sensitivity to gamma-irradiation_Brca1<tm1Cxd>/Brca1<tm1Cxd>
  http://metadb.riken.jp/0002007E129S6SvEvTacBrca1tm1CxdorI129S6SvEvBrdBlackSwissorI129S6SvEvBrdC57BL6Brca1tm1CxdBrca1tm1CxdBrca1tm1Cxd
• decreased embryo size_Brca1<tm1Cxd>/Brca1<tm1Cxd>,Trp53<tm1Brd>/Trp53<tm1Brd>
  http://metadb.riken.jp/0001698I129S6SvEvTac129S7SvEvBrdBrca1tm1CxdBrca1tm1CxdTrp53tm1BrdTrp53tm1BrdBrca1tm1CxdTrp53tm1Brd
• abnormal embryonic tissue morphology_Brca1<tm1Cxd>/Brca1<tm1Cxd>,Trp53<tm1Brd>/Trp53<tm1Brd>
  http://metadb.riken.jp/0002085I129S6SvEvTac129S7SvEvBrdBrca1tm1CxdBrca1tm1CxdTrp53tm1BrdTrp53tm1BrdBrca1tm1CxdTrp53tm1Brd
• abnormal primitive streak formation_Brca1<tm1Cxd>/Brca1<tm1Cxd>
  http://metadb.riken.jp/0002230E129S6SvEvTacBrca1tm1CxdorI129S6SvEvBrdBlackSwissorI129S6SvEvBrdC57BL6Brca1tm1CxdBrca1tm1CxdBrca1tm1Cxd
• abnormal chromosome number_Brca1<tm1Cxd>/Brca1<tm1Cxd>,Trp53<tm1Brd>/Trp53<tm1Brd>
  http://metadb.riken.jp/0004023I129S6SvEvTac129S7SvEvBrdBrca1tm1CxdBrca1tm1CxdTrp53tm1BrdTrp53tm1BrdBrca1tm1CxdTrp53tm1Brd
• abnormal embryonic tissue morphology_Brca1<tm1Cxd>/Brca1<tm1Cxd>
  http://metadb.riken.jp/0002085E129S6SvEvTacBrca1tm1CxdorI129S6SvEvBrdBlackSwissorI129S6SvEvBrdC57BL6Brca1tm1CxdBrca1tm1CxdBrca1tm1Cxd
• embryonic lethality between implantation and placentation, complete penetrance_Brca1<tm1Cxd>/Brca1<tm1Cxd>
  http://metadb.riken.jp/0011095E129S6SvEvTacBrca1tm1CxdorI129S6SvEvBrdBlackSwissorI129S6SvEvBrdC57BL6Brca1tm1CxdBrca1tm1CxdBrca1tm1Cxd
• spontaneous chromosome breakage_Brca1<tm1Cxd>/Brca1<tm1Cxd>,Trp53<tm1Brd>/Trp53<tm1Brd>
  http://metadb.riken.jp/0004029I129S6SvEvTac129S7SvEvBrdBrca1tm1CxdBrca1tm1CxdTrp53tm1BrdTrp53tm1BrdBrca1tm1CxdTrp53tm1Brd
• embryonic lethality during organogenesis, complete penetrance_Brca1<tm1Cxd>/Brca1<tm1Cxd>,Trp53<tm1Brd>/Trp53<tm1Brd>
  http://metadb.riken.jp/0011098I129S6SvEvTac129S7SvEvBrdBrca1tm1CxdBrca1tm1CxdTrp53tm1BrdTrp53tm1BrdBrca1tm1CxdTrp53tm1Brd
• abnormal chromosome number_Brca1<tm1Cxd>/Brca1<tm1Cxd>
  http://metadb.riken.jp/0004023E129S6SvEvTacBrca1tm1CxdorI129S6SvEvBrdBlackSwissorI129S6SvEvBrdC57BL6Brca1tm1CxdBrca1tm1CxdBrca1tm1Cxd
• abnormal axial mesoderm_Brca1<tm1Cxd>/Brca1<tm1Cxd>
  http://metadb.riken.jp/0001684E129S6SvEvTacBrca1tm1CxdorI129S6SvEvBrdBlackSwissorI129S6SvEvBrdC57BL6Brca1tm1CxdBrca1tm1CxdBrca1tm1Cxd