Inik. Chang, et.al., Endothelin-2 deficiency causes growth retardation, hypothermia, and emphysema in mice., The Journal of clinical investigation, 2013, 123

http://rdf.ncbi.nlm.nih.gov/pubmed/23676500

Inik. Chang, et.al., Endothelin-2 deficiency causes growth retardation, hypothermia, and emphysema in mice., The Journal of clinical investigation, 2013, 123

rdfs:label

http://www.w3.org/2000/01/rdf-schema#label

• Inik. Chang, et.al., Endothelin-2 deficiency causes growth retardation, hypothermia, and emphysema in mice., The Journal of clinical investigation, 2013, 123

article

http://www.w3.org/2000/01/rdf-schema#seeAlso

• [Blank]

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• impaired adaptive thermogenesis_Edn2<tm1Ywa>/Edn2<tm1Ywa>
  http://metadb.riken.jp/0011049I129S6SvEvTacEdn2tm1YwaEdn2tm1YwaEdn2tm1Ywa
• decreased circulating glucose level_Edn2<tm1.1Nat>/Edn2<tm1.1Nat>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0005560I129S1Sv129X1SvJC57BL6CBAEdn2tm11NatEdn2tm11NatTgCAGcreEsr15Amc0Edn2tm11NatTgCAGcreEsr15Amc
• postnatal growth retardation_Edn2<tm1Ywa>/Edn2<tm1Ywa>
  http://metadb.riken.jp/0001732I129S6SvEvTacEdn2tm1YwaEdn2tm1YwaEdn2tm1Ywa
• decreased circulating triiodothyronine level_Edn2<tm1Ywa>/Edn2<tm1Ywa>
  http://metadb.riken.jp/0005479I129S6SvEvTacEdn2tm1YwaEdn2tm1YwaEdn2tm1Ywa
• acidosis_Edn2<tm1.1Nat>/Edn2<tm1.1Nat>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0003031I129S1Sv129X1SvJC57BL6CBAEdn2tm11NatEdn2tm11NatTgCAGcreEsr15Amc0Edn2tm11NatTgCAGcreEsr15Amc
• increased total lung capacity_Edn2<tm1Ywa>/Edn2<tm1Ywa>
  http://metadb.riken.jp/0010937I129S6SvEvTacEdn2tm1YwaEdn2tm1YwaEdn2tm1Ywa
• decreased body weight_Edn2<tm1Ywa>/Edn2<tm1Ywa>
  http://metadb.riken.jp/0001262I129S6SvEvTacEdn2tm1YwaEdn2tm1YwaEdn2tm1Ywa
• abnormal pulmonary alveolar sac morphology_Edn2<tm1.1Nat>/Edn2<tm1.1Nat>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0010902I129S1Sv129X1SvJC57BL6CBAEdn2tm11NatEdn2tm11NatTgCAGcreEsr15Amc0Edn2tm11NatTgCAGcreEsr15Amc
• increased circulating erythropoietin level_Edn2<tm1Ywa>/Edn2<tm1Ywa>
  http://metadb.riken.jp/0011285I129S6SvEvTacEdn2tm1YwaEdn2tm1YwaEdn2tm1Ywa
• postnatal growth retardation_Edn2<tm1.1Nat>/Edn2<tm1.1Nat>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0001732I129S1Sv129X1SvJC57BL6CBAEdn2tm11NatEdn2tm11NatTgCAGcreEsr15Amc0Edn2tm11NatTgCAGcreEsr15Amc
• abnormal lipolysis_Edn2<tm1Ywa>/Edn2<tm1Ywa>
  http://metadb.riken.jp/0008032I129S6SvEvTacEdn2tm1YwaEdn2tm1YwaEdn2tm1Ywa
• increased sensitivity to induced morbidity/mortality_Edn2<tm1Ywa>/Edn2<tm1Ywa>
  http://metadb.riken.jp/0009763I129S6SvEvTacEdn2tm1YwaEdn2tm1YwaEdn2tm1Ywa
• decreased body temperature_Edn2<tm1Ywa>/Edn2<tm1Ywa>
  http://metadb.riken.jp/0005534I129S6SvEvTacEdn2tm1YwaEdn2tm1YwaEdn2tm1Ywa
• increased circulating bicarbonate level_Edn2<tm1.1Nat>/Edn2<tm1.1Nat>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0003016I129S1Sv129X1SvJC57BL6CBAEdn2tm11NatEdn2tm11NatTgCAGcreEsr15Amc0Edn2tm11NatTgCAGcreEsr15Amc
• decreased body temperature_Edn2<tm1.1Nat>/Edn2<tm1.1Nat>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0005534I129S1Sv129X1SvJC57BL6CBAEdn2tm11NatEdn2tm11NatTgCAGcreEsr15Amc0Edn2tm11NatTgCAGcreEsr15Amc
• postnatal lethality, incomplete penetrance_Edn2<tm1Ywa>/Edn2<tm1Ywa>
  http://metadb.riken.jp/0011086I129S6SvEvTacEdn2tm1YwaEdn2tm1YwaEdn2tm1Ywa
• increased hematocrit_Edn2<tm1Ywa>/Edn2<tm1Ywa>
  http://metadb.riken.jp/0002608I129S6SvEvTacEdn2tm1YwaEdn2tm1YwaEdn2tm1Ywa
• increased circulating ketone body level_Edn2<tm1Ywa>/Edn2<tm1Ywa>
  http://metadb.riken.jp/0002575I129S6SvEvTacEdn2tm1YwaEdn2tm1YwaEdn2tm1Ywa
• decreased circulating glucose level_Edn2<tm1Ywa>/Edn2<tm1Ywa>
  http://metadb.riken.jp/0005560I129S6SvEvTacEdn2tm1YwaEdn2tm1YwaEdn2tm1Ywa
• abnormal brown adipose tissue morphology_Edn2<tm1Ywa>/Edn2<tm1Ywa>
  http://metadb.riken.jp/0002971I129S6SvEvTacEdn2tm1YwaEdn2tm1YwaEdn2tm1Ywa
• postnatal lethality, incomplete penetrance_Edn2<tm1.1Nat>/Edn2<tm1.1Nat>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0011086I129S1Sv129X1SvJC57BL6CBAEdn2tm11NatEdn2tm11NatTgCAGcreEsr15Amc0Edn2tm11NatTgCAGcreEsr15Amc
• premature death_Edn2<tm1.1Nat>/Edn2<tm1.1Nat>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0002083I129S1Sv129X1SvJC57BL6CBAEdn2tm11NatEdn2tm11NatTgCAGcreEsr15Amc0Edn2tm11NatTgCAGcreEsr15Amc
• increased circulating bicarbonate level_Edn2<tm1Ywa>/Edn2<tm1Ywa>
  http://metadb.riken.jp/0003016I129S6SvEvTacEdn2tm1YwaEdn2tm1YwaEdn2tm1Ywa
• abnormal pulmonary alveolar sac morphology_Edn2<tm1Ywa>/Edn2<tm1Ywa>
  http://metadb.riken.jp/0010902I129S6SvEvTacEdn2tm1YwaEdn2tm1YwaEdn2tm1Ywa
• abnormal gas homeostasis_Edn2<tm1Ywa>/Edn2<tm1Ywa>
  http://metadb.riken.jp/0003948I129S6SvEvTacEdn2tm1YwaEdn2tm1YwaEdn2tm1Ywa
• abnormal pulmonary alveolus morphology_Edn2<tm1.1Nat>/Edn2<tm1.1Nat>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0002270I129S1Sv129X1SvJC57BL6CBAEdn2tm11NatEdn2tm11NatTgCAGcreEsr15Amc0Edn2tm11NatTgCAGcreEsr15Amc
• premature death_Edn2<tm1Ywa>/Edn2<tm1Ywa>
  http://metadb.riken.jp/0002083I129S6SvEvTacEdn2tm1YwaEdn2tm1YwaEdn2tm1Ywa
• increased blood urea nitrogen level_Edn2<tm1Ywa>/Edn2<tm1Ywa>
  http://metadb.riken.jp/0005565I129S6SvEvTacEdn2tm1YwaEdn2tm1YwaEdn2tm1Ywa
• increased blood uric acid level_Edn2<tm1Ywa>/Edn2<tm1Ywa>
  http://metadb.riken.jp/0008821I129S6SvEvTacEdn2tm1YwaEdn2tm1YwaEdn2tm1Ywa
• hypercapnia_Edn2<tm1Ywa>/Edn2<tm1Ywa>
  http://metadb.riken.jp/0002318I129S6SvEvTacEdn2tm1YwaEdn2tm1YwaEdn2tm1Ywa
• hypercapnia_Edn2<tm1.1Nat>/Edn2<tm1.1Nat>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0002318I129S1Sv129X1SvJC57BL6CBAEdn2tm11NatEdn2tm11NatTgCAGcreEsr15Amc0Edn2tm11NatTgCAGcreEsr15Amc
• decreased body weight_Edn2<tm1.1Nat>/Edn2<tm1.1Nat>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0001262I129S1Sv129X1SvJC57BL6CBAEdn2tm11NatEdn2tm11NatTgCAGcreEsr15Amc0Edn2tm11NatTgCAGcreEsr15Amc
• impaired adaptive thermogenesis_Edn2<tm1.1Nat>/Edn2<tm1.1Nat>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0011049I129S1Sv129X1SvJC57BL6CBAEdn2tm11NatEdn2tm11NatTgCAGcreEsr15Amc0Edn2tm11NatTgCAGcreEsr15Amc
• decreased total body fat amount_Edn2<tm1.1Nat>/Edn2<tm1.1Nat>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0010025I129S1Sv129X1SvJC57BL6CBAEdn2tm11NatEdn2tm11NatTgCAGcreEsr15Amc0Edn2tm11NatTgCAGcreEsr15Amc
• abnormal blood homeostasis_Edn2<tm1Ywa>/Edn2<tm1Ywa>
  http://metadb.riken.jp/0009642I129S6SvEvTacEdn2tm1YwaEdn2tm1YwaEdn2tm1Ywa
• decreased body size_Edn2<tm1Ywa>/Edn2<tm1Ywa>
  http://metadb.riken.jp/0001265I129S6SvEvTacEdn2tm1YwaEdn2tm1YwaEdn2tm1Ywa
• acidemia_Edn2<tm1.1Nat>/Edn2<tm1.1Nat>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0003030I129S1Sv129X1SvJC57BL6CBAEdn2tm11NatEdn2tm11NatTgCAGcreEsr15Amc0Edn2tm11NatTgCAGcreEsr15Amc
• abnormal pulmonary alveolus morphology_Edn2<tm1Ywa>/Edn2<tm1Ywa>
  http://metadb.riken.jp/0002270I129S6SvEvTacEdn2tm1YwaEdn2tm1YwaEdn2tm1Ywa
• acidosis_Edn2<tm1Ywa>/Edn2<tm1Ywa>
  http://metadb.riken.jp/0003031I129S6SvEvTacEdn2tm1YwaEdn2tm1YwaEdn2tm1Ywa
• hypoxia_Edn2<tm1Ywa>/Edn2<tm1Ywa>
  http://metadb.riken.jp/0005039I129S6SvEvTacEdn2tm1YwaEdn2tm1YwaEdn2tm1Ywa
• acidemia_Edn2<tm1Ywa>/Edn2<tm1Ywa>
  http://metadb.riken.jp/0003030I129S6SvEvTacEdn2tm1YwaEdn2tm1YwaEdn2tm1Ywa

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal pulmonary alveolus morphology in RBRC06164
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1009121
• increased circulating ketone body level in RBRC06164
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1009123
• postnatal growth retardation in RBRC06164
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1009119
• increased total lung capacity in RBRC06164
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1009140
• increased circulating erythropoietin level in RBRC06164
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1009143
• hypoxia in RBRC06164
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1009130
• acidemia in RBRC06164
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1009127
• abnormal blood homeostasis in RBRC06164
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1009137
• increased hematocrit in RBRC06164
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1009124
• abnormal body temperature homeostasis in RBRC06164
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1014613
• acidosis in RBRC06164
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1009128
• impaired adaptive thermogenesis in RBRC06164
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1009141
• increased blood uric acid level in RBRC06164
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1009136
• decreased body size in RBRC06164
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1009118
• abnormal lipolysis in RBRC06164
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1009135
• hypercapnia in RBRC06164
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1009122
• homeostasis/metabolism phenotype in RBRC06164
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1015984
• premature death in RBRC06164
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1009120
• decreased body weight in RBRC06164
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1009117
• abnormal brown adipose tissue morphology in RBRC06164
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1009125
• digestive/alimentary phenotype in RBRC06164
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1015985
• postnatal lethality, incomplete penetrance in RBRC06164
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1009142
• abnormal pulmonary alveolar sac morphology in RBRC06164
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1009139
• increased circulating bicarbonate level in RBRC06164
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1009126
• decreased body temperature in RBRC06164
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1009132
• abnormal gas homeostasis in RBRC06164
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1009129
• increased blood urea nitrogen level in RBRC06164
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1009134
• decreased circulating glucose level in RBRC06164
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1009133
• decreased circulating triiodothyronine level in RBRC06164
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1009131
• increased sensitivity to induced morbidity/mortality in RBRC06164
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1009138

Class

http://purl.org/net/cito/citesAsAuthority

• B6;129-Edn2<tm1Ywa>
  http://metadb.riken.jp/db/rikenbrc_mouse/RBRC06164

class

http://purl.org/net/cito/citesAsAuthority

• Edn2<tm1Ywa>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5519239

BRC マウスの系統

http://purl.org/net/cito/citesAsAuthority

• B6;129-Edn2<tm1Ywa>
  http://metadb.riken.jp/db/rikenbrc_mouse/RBRC06164

allele

http://purl.org/net/cito/citesAsAuthority

• Edn2<tm1Ywa>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5519239