Amanda. Sainsbury, et.al., Y4 receptor knockout rescues fertility in ob/ob mice., Genes & development, 2002, 16

http://rdf.ncbi.nlm.nih.gov/pubmed/12000791

Amanda. Sainsbury, et.al., Y4 receptor knockout rescues fertility in ob/ob mice., Genes & development, 2002, 16

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased circulating corticosterone level in RBRC03708
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1010707
• increased circulating leptin level in RBRC03708
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1006426
• prolonged estrus in RBRC03708
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1006441
• increased liver weight in RBRC03708
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1010711
• prolonged diestrus in RBRC03708
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1006440
• decreased seminal vesicle weight in RBRC03708
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1006408
• abnormal circulating hormone level in RBRC03708
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1006420
• decreased circulating testosterone level in RBRC03708
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1006377
• prolonged estrous cycle in RBRC03708
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1006439
• abnormal circulating pancreatic peptide level in RBRC03708
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1006432
• abnormal ovarian folliculogenesis in RBRC03708
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1006346
• decreased testis weight in RBRC03708
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1006406
• abnormal vagina orifice morphology in RBRC03708
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1006348
• absent corpus luteum in RBRC03708
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1006347
• abnormal branching of the mammary ductal tree in RBRC03708
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1006345

allele

http://purl.org/net/cito/citesAsAuthority

• Npy4r<tm1.1Hhz>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2183929
• Npy4r<tm1Hhz>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2183928

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• male infertility_Lep<ob>/Lep<ob>
  http://metadb.riken.jp/0001925I129X1SvJC57BL6LepobLepobLepob
• abnormal adipose tissue amount_Lep<ob>/Lep<ob>,Npy4r<tm1.1Hhz>/Npy4r<tm1.1Hhz>
  http://metadb.riken.jp/0005452I129X1SvJC57BL6LepobLepobNpy4rtm11HhzNpy4rtm11HhzLepobNpy4rtm11Hhz
• abnormal circulating testosterone level_Lep<ob>/Lep<ob>,Npy4r<tm1.1Hhz>/Npy4r<tm1.1Hhz>
  http://metadb.riken.jp/0005180I129X1SvJC57BL6LepobLepobNpy4rtm11HhzNpy4rtm11HhzLepobNpy4rtm11Hhz
• prolonged estrus_Lep<ob>/Lep<ob>
  http://metadb.riken.jp/0009017I129X1SvJC57BL6LepobLepobLepob
• abnormal vagina orifice morphology_Lep<ob>/Lep<ob>
  http://metadb.riken.jp/0001142I129X1SvJC57BL6LepobLepobLepob
• abnormal fertility/fecundity_Lep<ob>/Lep<ob>,Npy4r<tm1.1Hhz>/Npy4r<tm1.1Hhz>
  http://metadb.riken.jp/0002161I129X1SvJC57BL6LepobLepobNpy4rtm11HhzNpy4rtm11HhzLepobNpy4rtm11Hhz
• abnormal circulating pancreatic peptide level_Npy4r<tm1.1Hhz>/Npy4r<tm1.1Hhz>
  http://metadb.riken.jp/0008459I129X1SvJC57BL6Npy4rtm11HhzNpy4rtm11HhzNpy4rtm11Hhz
• decreased testis weight_Lep<ob>/Lep<ob>
  http://metadb.riken.jp/0004852I129X1SvJC57BL6LepobLepobLepob
• decreased seminal vesicle weight_Lep<ob>/Lep<ob>
  http://metadb.riken.jp/0004910I129X1SvJC57BL6LepobLepobLepob
• abnormal branching of the mammary ductal tree_Lep<ob>/Lep<ob>,Npy4r<tm1.1Hhz>/Npy4r<tm1.1Hhz>
  http://metadb.riken.jp/0000662I129X1SvJC57BL6LepobLepobNpy4rtm11HhzNpy4rtm11HhzLepobNpy4rtm11Hhz
• increased circulating insulin level_Lep<ob>/Lep<ob>
  http://metadb.riken.jp/0002079I129X1SvJC57BL6LepobLepobLepob
• increased circulating corticosterone level_Lep<ob>/Lep<ob>
  http://metadb.riken.jp/0001745I129X1SvJC57BL6LepobLepobLepob
• prolonged diestrus_Lep<ob>/Lep<ob>
  http://metadb.riken.jp/0009011I129X1SvJC57BL6LepobLepobLepob
• female infertility_Lep<ob>/Lep<ob>,Npy2r<tm1.1Hhz>/Npy2r<tm1.1Hhz>
  http://metadb.riken.jp/0001926I129X1SvJC57BL6LepobLepobNpy2rtm11HhzNpy2rtm11HhzNpy2rtm11HhzLepob
• increased seminal vesicle weight_Lep<ob>/Lep<ob>,Npy4r<tm1.1Hhz>/Npy4r<tm1.1Hhz>
  http://metadb.riken.jp/0004909I129X1SvJC57BL6LepobLepobNpy4rtm11HhzNpy4rtm11HhzLepobNpy4rtm11Hhz
• abnormal circulating hormone level_Lep<ob>/Lep<ob>
  http://metadb.riken.jp/0005418I129X1SvJC57BL6LepobLepobLepob
• abnormal sperm number_Lep<ob>/Lep<ob>,Npy4r<tm1.1Hhz>/Npy4r<tm1.1Hhz>
  http://metadb.riken.jp/0002673I129X1SvJC57BL6LepobLepobNpy4rtm11HhzNpy4rtm11HhzLepobNpy4rtm11Hhz
• increased circulating leptin level_Lep<ob>/Lep<ob>
  http://metadb.riken.jp/0005669I129X1SvJC57BL6LepobLepobLepob
• prolonged estrous cycle_Lep<ob>/Lep<ob>
  http://metadb.riken.jp/0009006I129X1SvJC57BL6LepobLepobLepob
• increased susceptibility to weight gain_Lep<ob>/Lep<ob>,Npy4r<tm1.1Hhz>/Npy4r<tm1.1Hhz>
  http://metadb.riken.jp/0005455I129X1SvJC57BL6LepobLepobNpy4rtm11HhzNpy4rtm11HhzLepobNpy4rtm11Hhz
• increased body weight_Lep<ob>/Lep<+>,Npy4r<tm1.1Hhz>/Npy4r<tm1.1Hhz>
  http://metadb.riken.jp/0001260I129X1SvJC57BL6LepobLepNpy4rtm11HhzNpy4rtm11HhzLepLepobNpy4rtm11Hhz
• absent corpus luteum_Lep<ob>/Lep<ob>
  http://metadb.riken.jp/0001134I129X1SvJC57BL6LepobLepobLepob
• increased circulating corticosterone level_Lep<ob>/Lep<ob>,Npy4r<tm1.1Hhz>/Npy4r<tm1.1Hhz>
  http://metadb.riken.jp/0001745I129X1SvJC57BL6LepobLepobNpy4rtm11HhzNpy4rtm11HhzLepobNpy4rtm11Hhz
• abnormal ovarian folliculogenesis_Lep<ob>/Lep<ob>
  http://metadb.riken.jp/0001130I129X1SvJC57BL6LepobLepobLepob
• abnormal estrous cycle_Lep<ob>/Lep<ob>,Npy4r<tm1.1Hhz>/Npy4r<tm1.1Hhz>
  http://metadb.riken.jp/0001927I129X1SvJC57BL6LepobLepobNpy4rtm11HhzNpy4rtm11HhzLepobNpy4rtm11Hhz
• abnormal fat pad morphology_Npy4r<tm1.1Hhz>/Npy4r<tm1.1Hhz>
  http://metadb.riken.jp/0005334I129X1SvJC57BL6Npy4rtm11HhzNpy4rtm11HhzNpy4rtm11Hhz
• abnormal Leydig cell morphology_Lep<ob>/Lep<ob>,Npy4r<tm1.1Hhz>/Npy4r<tm1.1Hhz>
  http://metadb.riken.jp/0002786I129X1SvJC57BL6LepobLepobNpy4rtm11HhzNpy4rtm11HhzLepobNpy4rtm11Hhz
• increased white adipose tissue amount_Lep<ob>/Lep<+>,Npy4r<tm1.1Hhz>/Npy4r<tm1.1Hhz>
  http://metadb.riken.jp/0000008I129X1SvJC57BL6LepobLepNpy4rtm11HhzNpy4rtm11HhzLepLepobNpy4rtm11Hhz
• abnormal circulating pancreatic peptide level_Lep<ob>/Lep<ob>
  http://metadb.riken.jp/0008459I129X1SvJC57BL6LepobLepobLepob
• increased aggression towards mice_Npy4r<tm1.1Hhz>/Npy4r<tm1.1Hhz>
  http://metadb.riken.jp/0001353I129X1SvJC57BL6Npy4rtm11HhzNpy4rtm11HhzNpy4rtm11Hhz
• abnormal mammary gland growth during pregnancy_Npy4r<tm1.1Hhz>/Npy4r<tm1.1Hhz>
  http://metadb.riken.jp/0006269I129X1SvJC57BL6Npy4rtm11HhzNpy4rtm11HhzNpy4rtm11Hhz
• male infertility_Lep<ob>/Lep<ob>,Npy2r<tm1.1Hhz>/Npy2r<tm1.1Hhz>
  http://metadb.riken.jp/0001925I129X1SvJC57BL6LepobLepobNpy2rtm11HhzNpy2rtm11HhzNpy2rtm11HhzLepob
• abnormal ovarian follicle morphology_Lep<ob>/Lep<ob>,Npy4r<tm1.1Hhz>/Npy4r<tm1.1Hhz>
  http://metadb.riken.jp/0001131I129X1SvJC57BL6LepobLepobNpy4rtm11HhzNpy4rtm11HhzLepobNpy4rtm11Hhz
• increased liver weight_Lep<ob>/Lep<+>
  http://metadb.riken.jp/0002981I129X1SvJC57BL6LepobLepLepLepob
• abnormal food intake_Npy4r<tm1.1Hhz>/Npy4r<tm1.1Hhz>
  http://metadb.riken.jp/0005449I129X1SvJC57BL6Npy4rtm11HhzNpy4rtm11HhzNpy4rtm11Hhz
• female infertility_Lep<ob>/Lep<ob>
  http://metadb.riken.jp/0001926I129X1SvJC57BL6LepobLepobLepob
• abnormal vagina orifice morphology_Lep<ob>/Lep<ob>,Npy4r<tm1.1Hhz>/Npy4r<tm1.1Hhz>
  http://metadb.riken.jp/0001142I129X1SvJC57BL6LepobLepobNpy4rtm11HhzNpy4rtm11HhzLepobNpy4rtm11Hhz
• decreased body weight_Npy4r<tm1.1Hhz>/Npy4r<tm1.1Hhz>
  http://metadb.riken.jp/0001262I129X1SvJC57BL6Npy4rtm11HhzNpy4rtm11HhzNpy4rtm11Hhz
• decreased circulating testosterone level_Lep<ob>/Lep<ob>
  http://metadb.riken.jp/0002780I129X1SvJC57BL6LepobLepobLepob
• decreased white adipose tissue amount_Npy4r<tm1.1Hhz>/Npy4r<tm1.1Hhz>
  http://metadb.riken.jp/0001783I129X1SvJC57BL6Npy4rtm11HhzNpy4rtm11HhzNpy4rtm11Hhz
• abnormal branching of the mammary ductal tree_Lep<ob>/Lep<ob>
  http://metadb.riken.jp/0000662I129X1SvJC57BL6LepobLepobLepob