Yoshihide. Ueda, et.al., Roles for Dnmt3b in mammalian development: a mouse model for the ICF syndrome., Development (Cambridge, England), 2006, 133

http://rdf.ncbi.nlm.nih.gov/pubmed/16501171

Yoshihide. Ueda, et.al., Roles for Dnmt3b in mammalian development: a mouse model for the ICF syndrome., Development (Cambridge, England), 2006, 133

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• small liver in RBRC03732
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1006480
• embryonic lethality during organogenesis, incomplete penetrance in RBRC03732
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1006486
• abnormal interventricular septum morphology in RBRC03732
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1006479
• hemorrhage in RBRC03732
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1006482
• lethality throughout fetal growth and development, complete penetrance in RBRC03732
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1006485

allele

http://purl.org/net/cito/citesAsAuthority

• Dnmt3b<tm6Enl>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3628446
• Dnmt3b<tm7Enl>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3628447

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased birth weight_Dnmt3b<tm1Enl>/Dnmt3b<tm7Enl>
  http://metadb.riken.jp/0009674I129S4SvJaeC57BL6Dnmt3btm1EnlDnmt3btm7EnlDnmt3btm1EnlDnmt3btm7Enl
• neonatal lethality, complete penetrance_Dnmt3b<tm1Enl>/Dnmt3b<tm7Enl>
  http://metadb.riken.jp/0011087I129S4SvJaeC57BL6Dnmt3btm1EnlDnmt3btm7EnlDnmt3btm1EnlDnmt3btm7Enl
• neonatal lethality, incomplete penetrance_Dnmt3b<tm7Enl>/Dnmt3b<tm7Enl>
  http://metadb.riken.jp/0011088I129S4SvJaeC57BL6Dnmt3btm7EnlDnmt3btm7EnlDnmt3btm7Enl
• small thymus_Dnmt3b<tm7Enl>/Dnmt3b<tm7Enl>
  http://metadb.riken.jp/0000706I129S4SvJaeC57BL6Dnmt3btm7EnlDnmt3btm7EnlDnmt3btm7Enl
• postnatal lethality, complete penetrance_Dnmt3b<tm6Enl>/Dnmt3b<tm7Enl>
  http://metadb.riken.jp/0011085I129S4SvJaeC57BL6Dnmt3btm6EnlDnmt3btm7EnlDnmt3btm6EnlDnmt3btm7Enl
• decreased thymocyte number_Dnmt3b<tm1Enl>/Dnmt3b<tm6Enl>
  http://metadb.riken.jp/0000715I129S4SvJaeC57BL6Dnmt3btm1EnlDnmt3btm6EnlDnmt3btm1EnlDnmt3btm6Enl
• increased thymocyte apoptosis_Dnmt3b<tm6Enl>/Dnmt3b<tm6Enl>
  http://metadb.riken.jp/0009541I129S4SvJaeC57BL6Dnmt3btm6EnlDnmt3btm6EnlDnmt3btm6Enl
• decreased birth weight_Dnmt3b<tm6Enl>/Dnmt3b<tm7Enl>
  http://metadb.riken.jp/0009674I129S4SvJaeC57BL6Dnmt3btm6EnlDnmt3btm7EnlDnmt3btm6EnlDnmt3btm7Enl
• increased double-negative T cell number_Dnmt3b<tm1Enl>/Dnmt3b<tm7Enl>
  http://metadb.riken.jp/0005090I129S4SvJaeC57BL6Dnmt3btm1EnlDnmt3btm7EnlDnmt3btm1EnlDnmt3btm7Enl
• decreased thymocyte number_Dnmt3b<tm1Enl>/Dnmt3b<tm7Enl>
  http://metadb.riken.jp/0000715I129S4SvJaeC57BL6Dnmt3btm1EnlDnmt3btm7EnlDnmt3btm1EnlDnmt3btm7Enl
• wide frontal bone_Dnmt3b<tm6Enl>/Dnmt3b<tm6Enl>
  http://metadb.riken.jp/0004379I129S4SvJaeC57BL6Dnmt3btm6EnlDnmt3btm6EnlDnmt3btm6Enl
• small thymus_Dnmt3b<tm1Enl>/Dnmt3b<tm7Enl>
  http://metadb.riken.jp/0000706I129S4SvJaeC57BL6Dnmt3btm1EnlDnmt3btm7EnlDnmt3btm1EnlDnmt3btm7Enl
• increased thymocyte apoptosis_Dnmt3b<tm7Enl>/Dnmt3b<tm7Enl>
  http://metadb.riken.jp/0009541I129S4SvJaeC57BL6Dnmt3btm7EnlDnmt3btm7EnlDnmt3btm7Enl
• decreased thymocyte number_Dnmt3b<tm6Enl>/Dnmt3b<tm7Enl>
  http://metadb.riken.jp/0000715I129S4SvJaeC57BL6Dnmt3btm6EnlDnmt3btm7EnlDnmt3btm6EnlDnmt3btm7Enl
• large anterior fontanelle_Dnmt3b<tm6Enl>/Dnmt3b<tm6Enl>
  http://metadb.riken.jp/0000085I129S4SvJaeC57BL6Dnmt3btm6EnlDnmt3btm6EnlDnmt3btm6Enl
• increased thymocyte apoptosis_Dnmt3b<tm6Enl>/Dnmt3b<tm7Enl>
  http://metadb.riken.jp/0009541I129S4SvJaeC57BL6Dnmt3btm6EnlDnmt3btm7EnlDnmt3btm6EnlDnmt3btm7Enl
• increased thymocyte apoptosis_Dnmt3b<tm1Enl>/Dnmt3b<tm6Enl>
  http://metadb.riken.jp/0009541I129S4SvJaeC57BL6Dnmt3btm1EnlDnmt3btm6EnlDnmt3btm1EnlDnmt3btm6Enl
• small thymus_Dnmt3b<tm6Enl>/Dnmt3b<tm6Enl>
  http://metadb.riken.jp/0000706I129S4SvJaeC57BL6Dnmt3btm6EnlDnmt3btm6EnlDnmt3btm6Enl
• small liver_Dnmt3b<tm1Enl>/Dnmt3b<tm1Enl>
  http://metadb.riken.jp/0000601I129S4SvJaeC57BL6Dnmt3btm1EnlDnmt3btm1EnlDnmt3btm1Enl
• small thymus_Dnmt3b<tm1Enl>/Dnmt3b<tm6Enl>
  http://metadb.riken.jp/0000706I129S4SvJaeC57BL6Dnmt3btm1EnlDnmt3btm6EnlDnmt3btm1EnlDnmt3btm6Enl
• hemorrhage_Dnmt3b<tm1Enl>/Dnmt3b<tm1Enl>
  http://metadb.riken.jp/0001914I129S4SvJaeC57BL6Dnmt3btm1EnlDnmt3btm1EnlDnmt3btm1Enl
• decreased thymocyte number_Dnmt3b<tm7Enl>/Dnmt3b<tm7Enl>
  http://metadb.riken.jp/0000715I129S4SvJaeC57BL6Dnmt3btm7EnlDnmt3btm7EnlDnmt3btm7Enl
• embryonic lethality during organogenesis, incomplete penetrance_Dnmt3b<tm1Enl>/Dnmt3b<tm1Enl>
  http://metadb.riken.jp/0011108I129S4SvJaeC57BL6Dnmt3btm1EnlDnmt3btm1EnlDnmt3btm1Enl
• abnormal nasal bone morphology_Dnmt3b<tm6Enl>/Dnmt3b<tm7Enl>
  http://metadb.riken.jp/0000102I129S4SvJaeC57BL6Dnmt3btm6EnlDnmt3btm7EnlDnmt3btm6EnlDnmt3btm7Enl
• abnormal interventricular septum morphology_Dnmt3b<tm1Enl>/Dnmt3b<tm1Enl>
  http://metadb.riken.jp/0000281I129S4SvJaeC57BL6Dnmt3btm1EnlDnmt3btm1EnlDnmt3btm1Enl
• neonatal lethality, incomplete penetrance_Dnmt3b<tm1Enl>/Dnmt3b<tm6Enl>
  http://metadb.riken.jp/0011088I129S4SvJaeC57BL6Dnmt3btm1EnlDnmt3btm6EnlDnmt3btm1EnlDnmt3btm6Enl
• decreased birth weight_Dnmt3b<tm6Enl>/Dnmt3b<tm6Enl>
  http://metadb.riken.jp/0009674I129S4SvJaeC57BL6Dnmt3btm6EnlDnmt3btm6EnlDnmt3btm6Enl
• decreased double-positive T cell number_Dnmt3b<tm1Enl>/Dnmt3b<tm7Enl>
  http://metadb.riken.jp/0005092I129S4SvJaeC57BL6Dnmt3btm1EnlDnmt3btm7EnlDnmt3btm1EnlDnmt3btm7Enl
• decreased birth weight_Dnmt3b<tm1Enl>/Dnmt3b<tm6Enl>
  http://metadb.riken.jp/0009674I129S4SvJaeC57BL6Dnmt3btm1EnlDnmt3btm6EnlDnmt3btm1EnlDnmt3btm6Enl
• neonatal lethality, incomplete penetrance_Dnmt3b<tm6Enl>/Dnmt3b<tm7Enl>
  http://metadb.riken.jp/0011088I129S4SvJaeC57BL6Dnmt3btm6EnlDnmt3btm7EnlDnmt3btm6EnlDnmt3btm7Enl
• ocular hypertelorism_Dnmt3b<tm6Enl>/Dnmt3b<tm6Enl>
  http://metadb.riken.jp/0001300I129S4SvJaeC57BL6Dnmt3btm6EnlDnmt3btm6EnlDnmt3btm6Enl
• increased thymocyte apoptosis_Dnmt3b<tm1Enl>/Dnmt3b<tm7Enl>
  http://metadb.riken.jp/0009541I129S4SvJaeC57BL6Dnmt3btm1EnlDnmt3btm7EnlDnmt3btm1EnlDnmt3btm7Enl
• postnatal lethality, complete penetrance_Dnmt3b<tm7Enl>/Dnmt3b<tm7Enl>
  http://metadb.riken.jp/0011085I129S4SvJaeC57BL6Dnmt3btm7EnlDnmt3btm7EnlDnmt3btm7Enl
• lethality throughout fetal growth and development, complete penetrance_Dnmt3b<tm1Enl>/Dnmt3b<tm1Enl>
  http://metadb.riken.jp/0011099I129S4SvJaeC57BL6Dnmt3btm1EnlDnmt3btm1EnlDnmt3btm1Enl
• decreased thymocyte number_Dnmt3b<tm6Enl>/Dnmt3b<tm6Enl>
  http://metadb.riken.jp/0000715I129S4SvJaeC57BL6Dnmt3btm6EnlDnmt3btm6EnlDnmt3btm6Enl
• short nasal bone_Dnmt3b<tm6Enl>/Dnmt3b<tm6Enl>
  http://metadb.riken.jp/0004471I129S4SvJaeC57BL6Dnmt3btm6EnlDnmt3btm6EnlDnmt3btm6Enl
• neonatal lethality, incomplete penetrance_Dnmt3b<tm6Enl>/Dnmt3b<tm6Enl>
  http://metadb.riken.jp/0011088I129S4SvJaeC57BL6Dnmt3btm6EnlDnmt3btm6EnlDnmt3btm6Enl