Takashi. Nagaishi, et.al., SHP1 phosphatase-dependent T cell inhibition by CEACAM1 adhesion molecule isoforms., Immunity, 2006, 25

http://rdf.ncbi.nlm.nih.gov/pubmed/17081782

Takashi. Nagaishi, et.al., SHP1 phosphatase-dependent T cell inhibition by CEACAM1 adhesion molecule isoforms., Immunity, 2006, 25

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal T-helper 1 physiology in RBRC00522
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1013013
• colitis in RBRC00522
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1012996

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(CD2-Ceacam1*4L)1Rsb
  http://metadb.riken.jp/db/mgi_rdf/MGI:3695215
• Ceacam1<tm1Rsb>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3693674

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased T cell proliferation_Ceacam1<tm1Rsb>/Ceacam1<tm1Rsb>,Tg(Lck-cre)1Cwi/0
  http://metadb.riken.jp/0005348I129Ceacam1tm1RsbCeacam1tm1RsbTgLckcre1Cwi0TgLckcre1CwiCeacam1tm1Rsb
• abnormal CD4-positive, alpha-beta T cell physiology_Tg(CD2-Ceacam1*4L)1Rsb/0,Tg(TcraTcrb)425Cbn/0
  http://metadb.riken.jp/0005463IBALBcC57BL6TgCD2Ceacam14L1Rsb0TgTcraTcrb425Cbn0TgTcraTcrb425CbnTgCD2Ceacam14L1Rsb
• decreased T cell number_Tg(CD2-Ceacam1*4L)1Rsb/0
  http://metadb.riken.jp/0005018IC57BL6TgCD2Ceacam14L1Rsb0TgCD2Ceacam14L1Rsb
• increased interleukin-2 secretion_Ceacam1<tm1Rsb>/Ceacam1<tm1Rsb>,Tg(Lck-cre)1Cwi/0
  http://metadb.riken.jp/0008687I129Ceacam1tm1RsbCeacam1tm1RsbTgLckcre1Cwi0TgLckcre1CwiCeacam1tm1Rsb
• abnormal T-helper 1 physiology_Rag2<tm1Fwa>/Rag2<tm1Fwa>
  http://metadb.riken.jp/0005465I129SSvEvRag2tm1FwaRag2tm1FwaRag2tm1Fwa
• abnormal cytokine secretion_Ceacam1<tm1Rsb>/Ceacam1<tm1Rsb>,Tg(Lck-cre)1Cwi/0
  http://metadb.riken.jp/0003009I129Ceacam1tm1RsbCeacam1tm1RsbTgLckcre1Cwi0TgLckcre1CwiCeacam1tm1Rsb
• abnormal T cell physiology_Tg(CD2-Ceacam1*4L)1Rsb/0
  http://metadb.riken.jp/0002444IC57BL6TgCD2Ceacam14L1Rsb0TgCD2Ceacam14L1Rsb
• decreased T cell proliferation_Tg(CD2-Ceacam1*4L)1Rsb/0
  http://metadb.riken.jp/0005095IC57BL6TgCD2Ceacam14L1Rsb0TgCD2Ceacam14L1Rsb
• colitis_Rag2<tm1Fwa>/Rag2<tm1Fwa>
  http://metadb.riken.jp/0002816I129SSvEvRag2tm1FwaRag2tm1FwaRag2tm1Fwa
• increased interferon-gamma secretion_Ceacam1<tm1Rsb>/Ceacam1<tm1Rsb>,Tg(Lck-cre)1Cwi/0
  http://metadb.riken.jp/0008566I129Ceacam1tm1RsbCeacam1tm1RsbTgLckcre1Cwi0TgLckcre1CwiCeacam1tm1Rsb
• abnormal response to transplant_Rag2<tm1Fwa>/Rag2<tm1Fwa>
  http://metadb.riken.jp/0005671I129SSvEvRag2tm1FwaRag2tm1FwaRag2tm1Fwa
• decreased interleukin-2 secretion_Tg(CD2-Ceacam1*4L)1Rsb/0
  http://metadb.riken.jp/0008688IC57BL6TgCD2Ceacam14L1Rsb0TgCD2Ceacam14L1Rsb