Scott. Robertson, et.al., Insufficiency of Janus kinase 2-autonomous leptin receptor signals for most physiologic leptin actions., Diabetes, 2010, 59

http://rdf.ncbi.nlm.nih.gov/pubmed/20068132

Scott. Robertson, et.al., Insufficiency of Janus kinase 2-autonomous leptin receptor signals for most physiologic leptin actions., Diabetes, 2010, 59

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased CD4-positive, alpha beta T cell number in RBRC03708
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1006429
• decreased T cell proliferation in RBRC03708
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1006410
• decreased splenocyte number in RBRC03708
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1006449

allele

http://purl.org/net/cito/citesAsAuthority

• Lepr<tm4Mgmj>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4843181

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• insulin resistance_Lepr<db>/Lepr<db>
  http://metadb.riken.jp/0005331IC57BL6C57BLKSJLeprdbLeprdbLeprdb
• increased circulating glucose level_Lepr<tm4Mgmj>/Lepr<tm4Mgmj>
  http://metadb.riken.jp/0005559B6CgLeprtm4MgmjLeprtm4MgmjLeprtm4MgmjLeprtm4Mgmj
• abnormal female reproductive system morphology_Lepr<db>/Lepr<db>
  http://metadb.riken.jp/0001119IC57BL6C57BLKSJLeprdbLeprdbLeprdb
• increased body weight_Lepr<tm4Mgmj>/Lepr<tm4Mgmj>
  http://metadb.riken.jp/0001260B6CgLeprtm4MgmjLeprtm4MgmjLeprtm4MgmjLeprtm4Mgmj
• absent estrus_Lepr<tm1Mgmj>/Lepr<tm1Mgmj>
  http://metadb.riken.jp/0009021I129SvLeprtm1MgmjLeprtm1MgmjLeprtm1Mgmj
• decreased splenocyte number_Lep<ob>/Lep<ob>
  http://metadb.riken.jp/0009339IC57BL6LepobLepobLepob
• absent estrus_Lepr<db>/Lepr<db>
  http://metadb.riken.jp/0009021IC57BL6C57BLKSJLeprdbLeprdbLeprdb
• abnormal female reproductive system morphology_Lepr<tm4Mgmj>/Lepr<tm4Mgmj>
  http://metadb.riken.jp/0001119B6CgLeprtm4MgmjLeprtm4MgmjLeprtm4MgmjLeprtm4Mgmj
• decreased splenocyte number_Lepr<tm4Mgmj>/Lepr<tm4Mgmj>
  http://metadb.riken.jp/0009339B6CgLeprtm4MgmjLeprtm4MgmjLeprtm4MgmjLeprtm4Mgmj
• impaired glucose tolerance_Lepr<tm4Mgmj>/Lepr<tm4Mgmj>
  http://metadb.riken.jp/0005293B6CgLeprtm4MgmjLeprtm4MgmjLeprtm4MgmjLeprtm4Mgmj
• female infertility_Lepr<tm4Mgmj>/Lepr<tm4Mgmj>
  http://metadb.riken.jp/0001926B6CgLeprtm4MgmjLeprtm4MgmjLeprtm4MgmjLeprtm4Mgmj
• decreased CD4-positive, alpha beta T cell number_Lepr<tm4Mgmj>/Lepr<tm4Mgmj>
  http://metadb.riken.jp/0008075B6CgLeprtm4MgmjLeprtm4MgmjLeprtm4MgmjLeprtm4Mgmj
• decreased CD4-positive, alpha beta T cell number_Lep<ob>/Lep<ob>
  http://metadb.riken.jp/0008075IC57BL6LepobLepobLepob
• impaired glucose tolerance_Lepr<db>/Lepr<db>
  http://metadb.riken.jp/0005293IC57BL6C57BLKSJLeprdbLeprdbLeprdb
• increased body weight_Lepr<db>/Lepr<db>
  http://metadb.riken.jp/0001260IC57BL6C57BLKSJLeprdbLeprdbLeprdb
• increased percent body fat/body weight_Lepr<db>/Lepr<db>
  http://metadb.riken.jp/0005458IC57BL6C57BLKSJLeprdbLeprdbLeprdb
• absent estrous cycle_Lepr<tm1Mgmj>/Lepr<tm1Mgmj>
  http://metadb.riken.jp/0009009I129SvLeprtm1MgmjLeprtm1MgmjLeprtm1Mgmj
• absent estrous cycle_Lepr<db>/Lepr<db>
  http://metadb.riken.jp/0009009IC57BL6C57BLKSJLeprdbLeprdbLeprdb
• short femur_Lepr<tm4Mgmj>/Lepr<tm4Mgmj>
  http://metadb.riken.jp/0003109B6CgLeprtm4MgmjLeprtm4MgmjLeprtm4MgmjLeprtm4Mgmj
• decreased lean body mass_Lepr<tm4Mgmj>/Lepr<tm4Mgmj>
  http://metadb.riken.jp/0003961B6CgLeprtm4MgmjLeprtm4MgmjLeprtm4MgmjLeprtm4Mgmj
• increased circulating glucose level_Lepr<db>/Lepr<db>
  http://metadb.riken.jp/0005559IC57BL6C57BLKSJLeprdbLeprdbLeprdb
• abnormal eating behavior_Lepr<tm4Mgmj>/Lepr<tm4Mgmj>
  http://metadb.riken.jp/0001431B6CgLeprtm4MgmjLeprtm4MgmjLeprtm4MgmjLeprtm4Mgmj
• decreased body temperature_Lepr<tm4Mgmj>/Lepr<tm4Mgmj>
  http://metadb.riken.jp/0005534B6CgLeprtm4MgmjLeprtm4MgmjLeprtm4MgmjLeprtm4Mgmj
• female infertility_Lepr<tm1Mgmj>/Lepr<tm1Mgmj>
  http://metadb.riken.jp/0001926I129SvLeprtm1MgmjLeprtm1MgmjLeprtm1Mgmj
• short femur_Lepr<db>/Lepr<db>
  http://metadb.riken.jp/0003109IC57BL6C57BLKSJLeprdbLeprdbLeprdb
• insulin resistance_Lepr<tm4Mgmj>/Lepr<tm4Mgmj>
  http://metadb.riken.jp/0005331B6CgLeprtm4MgmjLeprtm4MgmjLeprtm4MgmjLeprtm4Mgmj
• abnormal eating behavior_Lepr<db>/Lepr<db>
  http://metadb.riken.jp/0001431IC57BL6C57BLKSJLeprdbLeprdbLeprdb
• decreased body length_Lepr<db>/Lepr<db>
  http://metadb.riken.jp/0001258IC57BL6C57BLKSJLeprdbLeprdbLeprdb
• decreased T cell proliferation_Lep<ob>/Lep<ob>
  http://metadb.riken.jp/0005095IC57BL6LepobLepobLepob
• decreased lean body mass_Lepr<db>/Lepr<db>
  http://metadb.riken.jp/0003961IC57BL6C57BLKSJLeprdbLeprdbLeprdb
• increased circulating insulin level_Lepr<tm4Mgmj>/Lepr<tm4Mgmj>
  http://metadb.riken.jp/0002079B6CgLeprtm4MgmjLeprtm4MgmjLeprtm4MgmjLeprtm4Mgmj
• decreased T cell proliferation_Lepr<tm4Mgmj>/Lepr<tm4Mgmj>
  http://metadb.riken.jp/0005095B6CgLeprtm4MgmjLeprtm4MgmjLeprtm4MgmjLeprtm4Mgmj
• absent estrous cycle_Lepr<tm4Mgmj>/Lepr<tm4Mgmj>
  http://metadb.riken.jp/0009009B6CgLeprtm4MgmjLeprtm4MgmjLeprtm4MgmjLeprtm4Mgmj
• decreased body length_Lepr<tm4Mgmj>/Lepr<tm4Mgmj>
  http://metadb.riken.jp/0001258B6CgLeprtm4MgmjLeprtm4MgmjLeprtm4MgmjLeprtm4Mgmj
• increased percent body fat/body weight_Lepr<tm4Mgmj>/Lepr<tm4Mgmj>
  http://metadb.riken.jp/0005458B6CgLeprtm4MgmjLeprtm4MgmjLeprtm4MgmjLeprtm4Mgmj
• absent estrus_Lepr<tm4Mgmj>/Lepr<tm4Mgmj>
  http://metadb.riken.jp/0009021B6CgLeprtm4MgmjLeprtm4MgmjLeprtm4MgmjLeprtm4Mgmj
• increased circulating insulin level_Lepr<db>/Lepr<db>
  http://metadb.riken.jp/0002079IC57BL6C57BLKSJLeprdbLeprdbLeprdb
• female infertility_Lepr<db>/Lepr<db>
  http://metadb.riken.jp/0001926IC57BL6C57BLKSJLeprdbLeprdbLeprdb