Ling. Yu, et.al., Integrin α1/Akita double-knockout mice on a Balb/c background develop advanced features of human diabetic nephropathy., Kidney international, 2012, 81

http://rdf.ncbi.nlm.nih.gov/pubmed/22297672

Ling. Yu, et.al., Integrin α1/Akita double-knockout mice on a Balb/c background develop advanced features of human diabetic nephropathy., Kidney international, 2012, 81

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• expanded mesangial matrix in RBRC02661
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1004839
• hyperglycemia in RBRC02659
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1014235
• albuminuria in RBRC02659
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1014245
• expanded mesangial matrix in RBRC02659
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1014269
• increased renal glomerular filtration rate in RBRC02659
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1014256
• abnormal kidney interstitium morphology in RBRC02661
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1004841
• hyperglycemia in RBRC02661
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1011693
• abnormal renal glomerulus morphology in RBRC02659
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1014255
• abnormal glomerular capillary morphology in RBRC02661
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1004838
• abnormal glomerular capillary morphology in RBRC02659
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1014268
• increased renal glomerulus basement membrane thickness in RBRC02661
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1004840
• premature death in RBRC02659
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1014239
• glomerulosclerosis in RBRC02659
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1014253
• abnormal renal glomerulus morphology in RBRC02661
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1004828
• renal glomerular protein deposits in RBRC02661
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1021653
• premature death in RBRC02661
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1011697
• albuminuria in RBRC02661
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1004818
• increased renal glomerular filtration rate in RBRC02661
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1004831
• increased renal glomerulus basement membrane thickness in RBRC02659
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1014270
• glomerulosclerosis in RBRC02661
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1004825
• abnormal kidney interstitium morphology in RBRC02659
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1014271

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• hyperglycemia_Ins2<Akita>/Ins2<Akita>,Itga1<tm1Gdnr>/Itga1<tm1Gdnr>
  http://metadb.riken.jp/0001559CCgIns2AkitaItga1tm1GdnrIns2AkitaIns2AkitaItga1tm1GdnrItga1tm1GdnrIns2AkitaItga1tm1Gdnr
• abnormal kidney interstitium morphology_Ins2<Akita>/Ins2<Akita>
  http://metadb.riken.jp/0011425CB6NIns2AkitaIns2AkitaIns2AkitaIns2Akita
• abnormal glomerular capillary morphology_Ins2<Akita>/Ins2<Akita>,Itga1<tm1Gdnr>/Itga1<tm1Gdnr>
  http://metadb.riken.jp/0011320CCgIns2AkitaItga1tm1GdnrIns2AkitaIns2AkitaItga1tm1GdnrItga1tm1GdnrIns2AkitaItga1tm1Gdnr
• albuminuria_Ins2<Akita>/Ins2<Akita>
  http://metadb.riken.jp/0002871CB6NIns2AkitaIns2AkitaIns2AkitaIns2Akita
• expanded mesangial matrix_Ins2<Akita>/Ins2<Akita>
  http://metadb.riken.jp/0011353CB6NIns2AkitaIns2AkitaIns2AkitaIns2Akita
• premature death_Ins2<Akita>/Ins2<Akita>
  http://metadb.riken.jp/0002083CB6NIns2AkitaIns2AkitaIns2AkitaIns2Akita
• increased renal glomerular filtration rate_Ins2<Akita>/Ins2<Akita>
  http://metadb.riken.jp/0005527CB6NIns2AkitaIns2AkitaIns2AkitaIns2Akita
• increased renal glomerular filtration rate_Ins2<Akita>/Ins2<+>
  http://metadb.riken.jp/0005527CB6NIns2AkitaIns2AkitaIns2Ins2AkitaIns2
• albuminuria_Ins2<Akita>/Ins2<+>
  http://metadb.riken.jp/0002871CB6NIns2AkitaIns2AkitaIns2Ins2AkitaIns2
• abnormal renal glomerulus morphology_Ins2<Akita>/Ins2<Akita>
  http://metadb.riken.jp/0005325CB6NIns2AkitaIns2AkitaIns2AkitaIns2Akita
• decreased body weight_Ins2<Akita>/Ins2<Akita>,Itga1<tm1Gdnr>/Itga1<tm1Gdnr>
  http://metadb.riken.jp/0001262CCgIns2AkitaItga1tm1GdnrIns2AkitaIns2AkitaItga1tm1GdnrItga1tm1GdnrIns2AkitaItga1tm1Gdnr
• decreased body weight_Ins2<Akita>/Ins2<Akita>
  http://metadb.riken.jp/0001262CB6NIns2AkitaIns2AkitaIns2AkitaIns2Akita
• increased renal glomerulus basement membrane thickness_Ins2<Akita>/Ins2<Akita>
  http://metadb.riken.jp/0011409CB6NIns2AkitaIns2AkitaIns2AkitaIns2Akita
• glomerulosclerosis_Ins2<Akita>/Ins2<Akita>,Itga1<tm1Gdnr>/Itga1<tm1Gdnr>
  http://metadb.riken.jp/0005264CCgIns2AkitaItga1tm1GdnrIns2AkitaIns2AkitaItga1tm1GdnrItga1tm1GdnrIns2AkitaItga1tm1Gdnr
• increased renal glomerular filtration rate_Ins2<Akita>/Ins2<Akita>,Itga1<tm1Gdnr>/Itga1<tm1Gdnr>
  http://metadb.riken.jp/0005527CCgIns2AkitaItga1tm1GdnrIns2AkitaIns2AkitaItga1tm1GdnrItga1tm1GdnrIns2AkitaItga1tm1Gdnr
• glomerulosclerosis_Ins2<Akita>/Ins2<Akita>
  http://metadb.riken.jp/0005264CB6NIns2AkitaIns2AkitaIns2AkitaIns2Akita
• increased renal glomerulus basement membrane thickness_Ins2<Akita>/Ins2<Akita>,Itga1<tm1Gdnr>/Itga1<tm1Gdnr>
  http://metadb.riken.jp/0011409CCgIns2AkitaItga1tm1GdnrIns2AkitaIns2AkitaItga1tm1GdnrItga1tm1GdnrIns2AkitaItga1tm1Gdnr
• expanded mesangial matrix_Ins2<Akita>/Ins2<Akita>,Itga1<tm1Gdnr>/Itga1<tm1Gdnr>
  http://metadb.riken.jp/0011353CCgIns2AkitaItga1tm1GdnrIns2AkitaIns2AkitaItga1tm1GdnrItga1tm1GdnrIns2AkitaItga1tm1Gdnr
• expanded mesangial matrix_Ins2<Akita>/Ins2<+>
  http://metadb.riken.jp/0011353CB6NIns2AkitaIns2AkitaIns2Ins2AkitaIns2
• hyperglycemia_Ins2<Akita>/Ins2<Akita>
  http://metadb.riken.jp/0001559CB6NIns2AkitaIns2AkitaIns2AkitaIns2Akita
• mesangiolysis_Ins2<Akita>/Ins2<Akita>,Itga1<tm1Gdnr>/Itga1<tm1Gdnr>
  http://metadb.riken.jp/0011430CCgIns2AkitaItga1tm1GdnrIns2AkitaIns2AkitaItga1tm1GdnrItga1tm1GdnrIns2AkitaItga1tm1Gdnr
• albuminuria_Ins2<Akita>/Ins2<Akita>,Itga1<tm1Gdnr>/Itga1<tm1Gdnr>
  http://metadb.riken.jp/0002871CCgIns2AkitaItga1tm1GdnrIns2AkitaIns2AkitaItga1tm1GdnrItga1tm1GdnrIns2AkitaItga1tm1Gdnr
• premature death_Ins2<Akita>/Ins2<Akita>,Itga1<tm1Gdnr>/Itga1<tm1Gdnr>
  http://metadb.riken.jp/0002083CCgIns2AkitaItga1tm1GdnrIns2AkitaIns2AkitaItga1tm1GdnrItga1tm1GdnrIns2AkitaItga1tm1Gdnr
• glomerulosclerosis_Ins2<Akita>/Ins2<+>
  http://metadb.riken.jp/0005264CB6NIns2AkitaIns2AkitaIns2Ins2AkitaIns2
• abnormal glomerular capillary morphology_Ins2<Akita>/Ins2<Akita>
  http://metadb.riken.jp/0011320CB6NIns2AkitaIns2AkitaIns2AkitaIns2Akita
• abnormal glomerular mesangium morphology_Ins2<Akita>/Ins2<Akita>,Itga1<tm1Gdnr>/Itga1<tm1Gdnr>
  http://metadb.riken.jp/0011339CCgIns2AkitaItga1tm1GdnrIns2AkitaIns2AkitaItga1tm1GdnrItga1tm1GdnrIns2AkitaItga1tm1Gdnr
• abnormal renal glomerulus morphology_Ins2<Akita>/Ins2<Akita>,Itga1<tm1Gdnr>/Itga1<tm1Gdnr>
  http://metadb.riken.jp/0005325CCgIns2AkitaItga1tm1GdnrIns2AkitaIns2AkitaItga1tm1GdnrItga1tm1GdnrIns2AkitaItga1tm1Gdnr
• abnormal kidney interstitium morphology_Ins2<Akita>/Ins2<Akita>,Itga1<tm1Gdnr>/Itga1<tm1Gdnr>
  http://metadb.riken.jp/0011425CCgIns2AkitaItga1tm1GdnrIns2AkitaIns2AkitaItga1tm1GdnrItga1tm1GdnrIns2AkitaItga1tm1Gdnr