Zijing. Sheng, et.al., 8-Oxoguanine causes neurodegeneration during MUTYH-mediated DNA base excision repair., The Journal of clinical investigation, 2012, 122

http://rdf.ncbi.nlm.nih.gov/pubmed/23143307

Zijing. Sheng, et.al., 8-Oxoguanine causes neurodegeneration during MUTYH-mediated DNA base excision repair., The Journal of clinical investigation, 2012, 122

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased susceptibility to neuronal excitotoxicity in RBRC02598
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1004807

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• microgliosis_Ogg1<tm1Skmi>/Ogg1<tm1Skmi>
  http://metadb.riken.jp/0008918I129SSvEvC57BL6JJclOgg1tm1SkmiOgg1tm1SkmiOgg1tm1Skmi
• increased susceptibility to neuronal excitotoxicity_Ogg1<tm1Skmi>/Ogg1<tm1Skmi>
  http://metadb.riken.jp/0008235I129SSvEvC57BL6JJclOgg1tm1SkmiOgg1tm1SkmiOgg1tm1Skmi
• decreased vertical activity_Nudt1<tm1Tts>/Nudt1<tm1Tts>,Ogg1<tm1Skmi>/Ogg1<tm1Skmi>
  http://metadb.riken.jp/0002757I129SSvEvC57BL6JJclNudt1tm1TtsNudt1tm1TtsOgg1tm1SkmiOgg1tm1SkmiNudt1tm1TtsOgg1tm1Skmi
• decreased susceptibility to neuronal excitotoxicity_Mutyh<tm1Yun>/Mutyh<tm1Yun>,Ogg1<tm1Skmi>/Ogg1<tm1Skmi>
  http://metadb.riken.jp/0008236I129SSvEvC57BL6JJclMutyhtm1YunMutyhtm1YunOgg1tm1SkmiOgg1tm1SkmiOgg1tm1SkmiMutyhtm1Yun
• decreased vertical activity_Ogg1<tm1Skmi>/Ogg1<tm1Skmi>
  http://metadb.riken.jp/0002757I129SSvEvC57BL6JJclOgg1tm1SkmiOgg1tm1SkmiOgg1tm1Skmi
• neurodegeneration_Ogg1<tm1Skmi>/Ogg1<tm1Skmi>
  http://metadb.riken.jp/0002229I129SSvEvC57BL6JJclOgg1tm1SkmiOgg1tm1SkmiOgg1tm1Skmi
• abnormal single-strand DNA break repair_Nudt1<tm1Tts>/Nudt1<tm1Tts>,Ogg1<tm1Skmi>/Ogg1<tm1Skmi>
  http://metadb.riken.jp/0010947I129SSvEvC57BL6JJclNudt1tm1TtsNudt1tm1TtsOgg1tm1SkmiOgg1tm1SkmiNudt1tm1TtsOgg1tm1Skmi
• microgliosis_Nudt1<tm1Tts>/Nudt1<tm1Tts>,Ogg1<tm1Skmi>/Ogg1<tm1Skmi>
  http://metadb.riken.jp/0008918I129SSvEvC57BL6JJclNudt1tm1TtsNudt1tm1TtsOgg1tm1SkmiOgg1tm1SkmiNudt1tm1TtsOgg1tm1Skmi
• increased susceptibility to neuronal excitotoxicity_Nudt1<tm1Tts>/Nudt1<tm1Tts>,Ogg1<tm1Skmi>/Ogg1<tm1Skmi>
  http://metadb.riken.jp/0008235I129SSvEvC57BL6JJclNudt1tm1TtsNudt1tm1TtsOgg1tm1SkmiOgg1tm1SkmiNudt1tm1TtsOgg1tm1Skmi
• decreased susceptibility to neuronal excitotoxicity_Mutyh<tm1Yun>/Mutyh<tm1Yun>
  http://metadb.riken.jp/0008236I129C57BL6JJclMutyhtm1YunMutyhtm1YunMutyhtm1Yun
• increased tumor incidence_Mutyh<tm1Yun>/Mutyh<tm1Yun>,Nudt1<tm1Tts>/Nudt1<tm1Tts>,Ogg1<tm1Skmi>/Ogg1<tm1Skmi>
  http://metadb.riken.jp/0002020B6JJcl129Mutyhtm1YunNudt1tm1TtsOgg1tm1SkmiMutyhtm1YunMutyhtm1YunNudt1tm1TtsNudt1tm1TtsOgg1tm1SkmiOgg1tm1SkmiOgg1tm1SkmiMutyhtm1YunNudt1tm1Tts
• hypoactivity_Ogg1<tm1Skmi>/Ogg1<tm1Skmi>
  http://metadb.riken.jp/0001402I129SSvEvC57BL6JJclOgg1tm1SkmiOgg1tm1SkmiOgg1tm1Skmi
• hypoactivity_Nudt1<tm1Tts>/Nudt1<tm1Tts>,Ogg1<tm1Skmi>/Ogg1<tm1Skmi>
  http://metadb.riken.jp/0001402I129SSvEvC57BL6JJclNudt1tm1TtsNudt1tm1TtsOgg1tm1SkmiOgg1tm1SkmiNudt1tm1TtsOgg1tm1Skmi
• abnormal motor capabilities/coordination/movement_Nudt1<tm1Tts>/Nudt1<tm1Tts>,Ogg1<tm1Skmi>/Ogg1<tm1Skmi>
  http://metadb.riken.jp/0002066I129SSvEvC57BL6JJclNudt1tm1TtsNudt1tm1TtsOgg1tm1SkmiOgg1tm1SkmiNudt1tm1TtsOgg1tm1Skmi
• neurodegeneration_Nudt1<tm1Tts>/Nudt1<tm1Tts>,Ogg1<tm1Skmi>/Ogg1<tm1Skmi>
  http://metadb.riken.jp/0002229I129SSvEvC57BL6JJclNudt1tm1TtsNudt1tm1TtsOgg1tm1SkmiOgg1tm1SkmiNudt1tm1TtsOgg1tm1Skmi