M. Rubinstein, et.al., Mice lacking dopamine D4 receptors are supersensitive to ethanol, cocaine, and methamphetamine., Cell, 1997, 90

http://rdf.ncbi.nlm.nih.gov/pubmed/9323127

M. Rubinstein, et.al., Mice lacking dopamine D4 receptors are supersensitive to ethanol, cocaine, and methamphetamine., Cell, 1997, 90

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• impaired behavioral response to addictive substance in RBRC02478
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1015310
• hypoactivity in RBRC02478
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1015309
• enhanced behavioral response to cocaine in RBRC02477
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1015283
• enhanced behavioral response to cocaine in RBRC02478
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1015306
• hyperactivity elicited by ethanol administration in RBRC02477
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1015285
• hyperactivity elicited by ethanol administration in RBRC02478
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1015308
• decreased exploration in new environment in RBRC02478
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1015305
• impaired behavioral response to addictive substance in RBRC02477
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1015287
• enhanced coordination in RBRC02477
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1015284
• enhanced coordination in RBRC02478
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1015307
• hypoactivity in RBRC02477
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1015286
• increased dopamine level in RBRC02477
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1015288

allele

http://purl.org/net/cito/citesAsAuthority

• Drd4<tm1Dkg>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2178631

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• enhanced coordination_Drd4<tm1Dkg>/Drd4<tm1Dkg>
  http://metadb.riken.jp/0003858I129P2OlaHsdC57BL6JDrd4tm1DkgDrd4tm1DkgDrd4tm1Dkg
• hyperactivity elicited by ethanol administration_Drd4<tm1Dkg>/Drd4<tm1Dkg>
  http://metadb.riken.jp/0002629I129P2OlaHsdC57BL6JDrd4tm1DkgDrd4tm1DkgDrd4tm1Dkg
• increased dopamine level_Drd4<tm1Dkg>/Drd4<tm1Dkg>
  http://metadb.riken.jp/0001906I129P2OlaHsdC57BL6JDrd4tm1DkgDrd4tm1DkgDrd4tm1Dkg
• decreased vertical activity_Drd4<tm1Dkg>/Drd4<tm1Dkg>
  http://metadb.riken.jp/0002757I129P2OlaHsdC57BL6JDrd4tm1DkgDrd4tm1DkgDrd4tm1Dkg
• impaired behavioral response to addictive substance_Drd4<tm1Dkg>/Drd4<tm1Dkg>
  http://metadb.riken.jp/0009750I129P2OlaHsdC57BL6JDrd4tm1DkgDrd4tm1DkgDrd4tm1Dkg
• hypoactivity_Drd4<tm1Dkg>/Drd4<tm1Dkg>
  http://metadb.riken.jp/0001402I129P2OlaHsdC57BL6JDrd4tm1DkgDrd4tm1DkgDrd4tm1Dkg
• enhanced behavioral response to cocaine_Drd4<tm1Dkg>/Drd4<tm1Dkg>
  http://metadb.riken.jp/0009754I129P2OlaHsdC57BL6JDrd4tm1DkgDrd4tm1DkgDrd4tm1Dkg