<p>4-hydroxy-2-oxovalerate aldolase, also called 4-hydroxy-2-ketovalerate aldolase and 2-oxo-4-hydroxypentanoate aldolase is part of the pathway for the meta-cleavage of catechol, and produces pyruvate and acetaldehyde [<cite idref="PUB00043000"/>]. Acetaldehyde is then converted by acetaldehyde dehydrogenase (acylating) (DmpF; <db_xref db="EC" dbkey="1.2.1.10"/>) to acetyl-CoA. The two enzymes are tightly associated.</p>