<p>Each member of this group contains five functional domains catalysing five sequential steps of the shikimate pathway. Each domain corresponds to a monofunctional prokaryotic enzyme of the same pathway: 3-dehydroquinate synthase (<db_xref db="INTERPRO" dbkey="IPR016303"/>), 3-dehydroquinate dehydratase (<db_xref db="PIRSF" dbkey="PIRSF001397"/>), shikimate 5-dehydrogenase (<db_xref db="PIRSF" dbkey="PIRSF000100"/>), shikimate kinase (<db_xref db="PIRSF" dbkey="PIRSF000702"/>), and 3-phosphoshikimate 1-carboxyvinyltransferase (<db_xref db="PIRSF" dbkey="PIRSF000505"/>). The multifunctional gene is regulated in response to amino acid limitation by coordinate regulation, which provides an economical means of simultaneously synthesizing five shikimate pathway enzymes.</p><p>For additional information please see [<cite idref="PUB00011135"/>, <cite idref="PUB00011136"/>].</p>