CD10228

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD10228

CD10228

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Pim3

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• proviral integration site 3

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• serine/threonine-protein kinase pim-3
• proviral integration site 3

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• BC026639
• KID-1/kinase induced by depolarization
• Kid1

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/223775

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• proviral integration site 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:1355297

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_145478

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000035828

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.400129

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=610580

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• Irène. Aksoy, et.al., Self-renewal of murine embryonic stem cells is supported by the serine/threonine kinases Pim-1 and Pim-3., Stem cells, 2007, 25
  http://rdf.ncbi.nlm.nih.gov/pubmed/17717068
• J D. Feldman, et.al., KID-1, a protein kinase induced by depolarization in brain., The Journal of biological chemistry, 1998, 273
  http://rdf.ncbi.nlm.nih.gov/pubmed/9632723
• Andrew. Macdonald, et.al., Pim kinases phosphorylate multiple sites on Bad and promote 14-3-3 binding and dissociation from Bcl-XL., BMC cell biology, 2006, 7
  http://rdf.ncbi.nlm.nih.gov/pubmed/16403219
• Peng. Zhang, et.al., Pim-3 is expressed in endothelial cells and promotes vascular tube formation., Journal of cellular physiology, 2009, 220
  http://rdf.ncbi.nlm.nih.gov/pubmed/19229879
• Ying-Wei. Lin, et.al., A small molecule inhibitor of Pim protein kinases blocks the growth of precursor T-cell lymphoblastic leukemia/lymphoma., Blood, 2010, 115
  http://rdf.ncbi.nlm.nih.gov/pubmed/19965690
• Nicola T. Wood, et.al., 14-3-3 Binding to Pim-phosphorylated Ser166 and Ser186 of human Mdm2--Potential interplay with the PKB/Akt pathway and p14(ARF)., FEBS letters, 2009, 583
  http://rdf.ncbi.nlm.nih.gov/pubmed/19166854
• Ji-Long. Chen, et.al., Pim-1 and Pim-2 kinases are required for efficient pre-B-cell transformation by v-Abl oncogene., Blood, 2008, 111
  http://rdf.ncbi.nlm.nih.gov/pubmed/18042805
• A. Eichmann, et.al., Developmental expression of pim kinases suggests functions also outside of the hematopoietic system., Oncogene, 2000, 19
  http://rdf.ncbi.nlm.nih.gov/pubmed/10713710
• Zanna. Beharry, et.al., The Pim protein kinases regulate energy metabolism and cell growth., Proceedings of the National Academy of Sciences of the United States of America, 2011, 108
  http://rdf.ncbi.nlm.nih.gov/pubmed/21187426
• Harald. Mikkers, et.al., Mice deficient for all PIM kinases display reduced body size and impaired responses to hematopoietic growth factors., Molecular and cellular biology, 2004, 24
  http://rdf.ncbi.nlm.nih.gov/pubmed/15199164

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• protein phosphorylation
  http://purl.obolibrary.org/obo/GO_0006468
• nucleotide binding
  http://purl.obolibrary.org/obo/GO_0000166
• apoptotic process
  http://purl.obolibrary.org/obo/GO_0006915
• protein binding
  http://purl.obolibrary.org/obo/GO_0005515
• histone phosphorylation
  http://purl.obolibrary.org/obo/GO_0016572
• ATP binding
  http://purl.obolibrary.org/obo/GO_0005524
• protein kinase activity
  http://purl.obolibrary.org/obo/GO_0004672
• negative regulation of apoptotic process
  http://purl.obolibrary.org/obo/GO_0043066
• protein autophosphorylation
  http://purl.obolibrary.org/obo/GO_0046777
• cell cycle
  http://purl.obolibrary.org/obo/GO_0007049
• kinase activity
  http://purl.obolibrary.org/obo/GO_0016301
• negative regulation of insulin secretion involved in cellular response to glucose stimulus
  http://purl.obolibrary.org/obo/GO_0061179
• regulation of mitotic cell cycle
  http://purl.obolibrary.org/obo/GO_0007346
• cytoplasm
  http://purl.obolibrary.org/obo/GO_0005737
• transferase activity, transferring phosphorus-containing groups
  http://purl.obolibrary.org/obo/GO_0016772
• phosphorylation
  http://purl.obolibrary.org/obo/GO_0016310
• transferase activity
  http://purl.obolibrary.org/obo/GO_0016740
• protein serine/threonine kinase activity
  http://purl.obolibrary.org/obo/GO_0004674

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName