CD15581

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD15581

CD15581

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Irf8

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• interferon regulatory factor 8

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• interferon consensus sequence binding protein 1
• interferon regulatory factor 8
• interferon consensus sequence-binding protein

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• ICSBP
• IRF-8
• Myls
• Icsbp1
• AI893568

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/15900

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• interferon regulatory factor 8
  http://metadb.riken.jp/db/mgi_rdf/MGI:96395

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_008320

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000041515

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.334861

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=601565

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• T. Holtschke, et.al., Immunodeficiency and chronic myelogenous leukemia-like syndrome in mice with a targeted mutation of the ICSBP gene., Cell, 1996, 87
  http://rdf.ncbi.nlm.nih.gov/pubmed/8861914
• Jianxun. Feng, et.al., IFN regulatory factor 8 restricts the size of the marginal zone and follicular B cell pools., Journal of immunology (Baltimore, Md. : 1950), 2011, 186
  http://rdf.ncbi.nlm.nih.gov/pubmed/21178004
• P H. Driggers, et.al., An interferon gamma-regulated protein that binds the interferon-inducible enhancer element of major histocompatibility complex class I genes., Proceedings of the National Academy of Sciences of the United States of America, 1990, 87
  http://rdf.ncbi.nlm.nih.gov/pubmed/2111015
• Weiqi. Huang, et.al., Interferon consensus sequence binding protein (ICSBP) decreases beta-catenin activity in myeloid cells by repressing GAS2 transcription., Molecular and cellular biology, 2010, 30
  http://rdf.ncbi.nlm.nih.gov/pubmed/20679491
• Y. Kanno, et.al., The genomic structure of the murine ICSBP gene reveals the presence of the gamma interferon-responsive element, to which an ISGF3 alpha subunit (or similar) molecule binds., Molecular and cellular biology, 1993, 13
  http://rdf.ncbi.nlm.nih.gov/pubmed/8321202
• C A. Kozak, et.al., Genomic cloning of mouse MIF (macrophage inhibitory factor) and genetic mapping of the human and mouse expressed gene and nine mouse pseudogenes., Genomics, 1995, 27
  http://rdf.ncbi.nlm.nih.gov/pubmed/7558020
• M S. Lyu, et.al., Genetic mapping of the human and mouse phospholipase C genes., Mammalian genome : official journal of the International Mammalian Genome Society, 1996, 7
  http://rdf.ncbi.nlm.nih.gov/pubmed/8672127
• http://rdf.ncbi.nlm.nih.gov/pubmed/20932939
• Amanda L. Blasius, et.al., Slc15a4, AP-3, and Hermansky-Pudlak syndrome proteins are required for Toll-like receptor signaling in plasmacytoid dendritic cells., Proceedings of the National Academy of Sciences of the United States of America, 2010, 107
  http://rdf.ncbi.nlm.nih.gov/pubmed/21045126
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• cellular response to lipopolysaccharide
  http://purl.obolibrary.org/obo/GO_0071222
• positive regulation of interleukin-12 production
  http://purl.obolibrary.org/obo/GO_0032735
• response to bacterium
  http://purl.obolibrary.org/obo/GO_0009617
• defense response to bacterium
  http://purl.obolibrary.org/obo/GO_0042742
• immune response
  http://purl.obolibrary.org/obo/GO_0006955
• phagocytosis
  http://purl.obolibrary.org/obo/GO_0006909
• defense response to protozoan
  http://purl.obolibrary.org/obo/GO_0042832
• transcription, DNA-templated
  http://purl.obolibrary.org/obo/GO_0006351
• regulation of transcription, DNA-templated
  http://purl.obolibrary.org/obo/GO_0006355
• protein binding
  http://purl.obolibrary.org/obo/GO_0005515
• transcription regulatory region DNA binding
  http://purl.obolibrary.org/obo/GO_0044212
• sequence-specific DNA binding transcription factor activity
  http://purl.obolibrary.org/obo/GO_0003700
• positive regulation of interferon-gamma production
  http://purl.obolibrary.org/obo/GO_0032729
• myeloid cell differentiation
  http://purl.obolibrary.org/obo/GO_0030099
• negative regulation of growth of symbiont in host
  http://purl.obolibrary.org/obo/GO_0044130
• positive regulation of transcription, DNA-templated
  http://purl.obolibrary.org/obo/GO_0045893
• DNA binding
  http://purl.obolibrary.org/obo/GO_0003677
• nucleus
  http://purl.obolibrary.org/obo/GO_0005634

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map05133

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Pertussis