CD28512

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD28512

CD28512

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Akt3

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• thymoma viral proto-oncogene 3

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• RAC-gamma serine/threonine-protein kinase
• RAC-PK-gamma
• protein kinase B gamma
• protein kinase Akt-3
• thymoma viral proto-oncogene 3

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• AI851531
• PKB gamma
• D930002M15Rik
• Nmf350

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/23797

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• thymoma viral proto-oncogene 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:1345147

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_011785

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000019699

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.235194

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=611223

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• Zai. Chang, et.al., Deletion of Akt1 causes heart defects and abnormal cardiomyocyte proliferation., Developmental biology, 2010, 347
  http://rdf.ncbi.nlm.nih.gov/pubmed/20816796
• F. Di Cunto, et.al., Defective neurogenesis in citron kinase knockout mice by altered cytokinesis and massive apoptosis., Neuron, 2000, 28
  http://rdf.ncbi.nlm.nih.gov/pubmed/11086988
• Satoko. Tokuda, et.al., A novel Akt3 mutation associated with enhanced kinase activity and seizure susceptibility in mice., Human molecular genetics, 2011, 20
  http://rdf.ncbi.nlm.nih.gov/pubmed/21159799
• S S. Murthy, et.al., Mapping of AKT3, encoding a member of the Akt/protein kinase B family, to human and rodent chromosomes by fluorescence in situ hybridization., Cytogenetics and cell genetics, 2000, 88
  http://rdf.ncbi.nlm.nih.gov/pubmed/10773662
• Andrew N. Macintyre, et.al., Protein kinase B controls transcriptional programs that direct cytotoxic T cell fate but is dispensable for T cell metabolism., Immunity, 2011, 34
  http://rdf.ncbi.nlm.nih.gov/pubmed/21295499
• D. Brodbeck, et.al., Two splice variants of protein kinase B gamma have different regulatory capacity depending on the presence or absence of the regulatory phosphorylation site serine 472 in the carboxyl-terminal hydrophobic domain., The Journal of biological chemistry, 2001, 276
  http://rdf.ncbi.nlm.nih.gov/pubmed/11387345
• Fei. Zhou, et.al., Akt/Protein kinase B is required for lymphatic network formation, remodeling, and valve development., The American journal of pathology, 2010, 177
  http://rdf.ncbi.nlm.nih.gov/pubmed/20724596
• S R. Datta, et.al., Cellular survival: a play in three Akts., Genes & development, 1999, 13
  http://rdf.ncbi.nlm.nih.gov/pubmed/10579998
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• D. Brodbeck, et.al., A human protein kinase Bgamma with regulatory phosphorylation sites in the activation loop and in the C-terminal hydrophobic domain., The Journal of biological chemistry, 1999, 274
  http://rdf.ncbi.nlm.nih.gov/pubmed/10092583

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• membrane
  http://purl.obolibrary.org/obo/GO_0016020
• protein kinase activity
  http://purl.obolibrary.org/obo/GO_0004672
• Golgi apparatus
  http://purl.obolibrary.org/obo/GO_0005794
• plasma membrane
  http://purl.obolibrary.org/obo/GO_0005886
• transferase activity, transferring phosphorus-containing groups
  http://purl.obolibrary.org/obo/GO_0016772
• transferase activity
  http://purl.obolibrary.org/obo/GO_0016740
• phosphorylation
  http://purl.obolibrary.org/obo/GO_0016310
• cellular response to insulin stimulus
  http://purl.obolibrary.org/obo/GO_0032869
• protein serine/threonine kinase activity
  http://purl.obolibrary.org/obo/GO_0004674
• soluble fraction
  http://purl.obolibrary.org/obo/GO_0005625
• peptidyl-threonine phosphorylation
  http://purl.obolibrary.org/obo/GO_0018107
• nucleotide binding
  http://purl.obolibrary.org/obo/GO_0000166
• ATP binding
  http://purl.obolibrary.org/obo/GO_0005524
• nucleus
  http://purl.obolibrary.org/obo/GO_0005634
• mitochondrial genome maintenance
  http://purl.obolibrary.org/obo/GO_0000002
• signal transduction
  http://purl.obolibrary.org/obo/GO_0007165
• positive regulation of sodium ion transport
  http://purl.obolibrary.org/obo/GO_0010765
• protein kinase C binding
  http://purl.obolibrary.org/obo/GO_0005080
• cytoplasm
  http://purl.obolibrary.org/obo/GO_0005737
• peptidyl-serine phosphorylation
  http://purl.obolibrary.org/obo/GO_0018105
• protein phosphorylation
  http://purl.obolibrary.org/obo/GO_0006468
• kinase activity
  http://purl.obolibrary.org/obo/GO_0016301

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map00000

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Non-small cell lung cancer