Satoko. Tokuda, et.al., A novel Akt3 mutation associated with enhanced kinase activity and seizure susceptibility in mice., Human molecular genetics, 2011, 20

http://rdf.ncbi.nlm.nih.gov/pubmed/21159799

Satoko. Tokuda, et.al., A novel Akt3 mutation associated with enhanced kinase activity and seizure susceptibility in mice., Human molecular genetics, 2011, 20

http://rdf.ncbi.nlm.nih.gov/pubmed/

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD28512
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD28512
• CD09619
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD09619

allele

http://purl.org/net/cito/citesAsAuthority

• Akt3<Nmf350>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4941186

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal neuron morphology_Akt3<Nmf350>/Akt3<Nmf350>
  http://metadb.riken.jp/0002882C57BL6JAkt3Nmf350Akt3Nmf350Akt3Nmf350Akt3Nmf350
• maximal tonic hindlimb extension seizures_Akt3<tm1Mbb>/Akt3<tm1Mbb>
  http://metadb.riken.jp/0002194IC57BL6JAkt3tm1MbbAkt3tm1MbbAkt3tm1Mbb
• tonic-clonic seizures_Akt3<Nmf350>/Akt3<+>
  http://metadb.riken.jp/0003997C57BL6JAkt3Nmf350Akt3Nmf350Akt3Akt3Akt3Nmf350
• abnormal seizure response to electrical stimulation_Fcgr2b<tm1Ttk>/Fcgr2b<tm1Ttk>
  http://metadb.riken.jp/0001650B6129S4Fcgr2btm1TtkFcgr2btm1TtkFcgr2btm1TtkFcgr2btm1Ttk
• abnormal seizure response to electrical stimulation_Akt3<Nmf350>/Akt3<Nmf350>
  http://metadb.riken.jp/0001650C57BL6JAkt3Nmf350Akt3Nmf350Akt3Nmf350Akt3Nmf350
• enlarged hippocampus_Akt3<Nmf350>/Akt3<Nmf350>
  http://metadb.riken.jp/0008282C57BL6JAkt3Nmf350Akt3Nmf350Akt3Nmf350Akt3Nmf350
• tonic-clonic seizures_Akt3<Nmf350>/Akt3<Nmf350>
  http://metadb.riken.jp/0003997C57BL6JAkt3Nmf350Akt3Nmf350Akt3Nmf350Akt3Nmf350
• abnormal seizure response to electrical stimulation_Akt3<tm1Mbb>/Akt3<tm1Mbb>
  http://metadb.riken.jp/0001650IC57BL6JAkt3tm1MbbAkt3tm1MbbAkt3tm1Mbb
• increased brain weight_Akt3<Nmf350>/Akt3<+>
  http://metadb.riken.jp/0002176C57BL6JAkt3Nmf350Akt3Nmf350Akt3Akt3Akt3Nmf350
• abnormal seizure response to electrical stimulation_Akt3<Nmf350>/Akt3<+>
  http://metadb.riken.jp/0001650C57BL6JAkt3Nmf350Akt3Nmf350Akt3Akt3Akt3Nmf350
• increased brain size_Akt3<Nmf350>/Akt3<+>
  http://metadb.riken.jp/0005238C57BL6JAkt3Nmf350Akt3Nmf350Akt3Akt3Akt3Nmf350
• ectopic cerebellar granule cells_Akt3<Nmf350>/Akt3<Nmf350>
  http://metadb.riken.jp/0002762C57BL6JAkt3Nmf350Akt3Nmf350Akt3Nmf350Akt3Nmf350
• maximal tonic hindlimb extension seizures_Akt3<Nmf350>/Akt3<+>
  http://metadb.riken.jp/0002194C57BL6JAkt3Nmf350Akt3Nmf350Akt3Akt3Akt3Nmf350
• sporadic seizures_Akt3<Nmf350>/Akt3<+>
  http://metadb.riken.jp/0000951C57BL6JAkt3Nmf350Akt3Nmf350Akt3Akt3Akt3Nmf350
• increased susceptibility to pharmacologically induced seizures_Akt3<Nmf350>/Akt3<+>
  http://metadb.riken.jp/0002906C57BL6JAkt3Nmf350Akt3Nmf350Akt3Akt3Akt3Nmf350
• maximal tonic hindlimb extension seizures_Akt3<Nmf350>/Akt3<Nmf350>
  http://metadb.riken.jp/0002194C57BL6JAkt3Nmf350Akt3Nmf350Akt3Nmf350Akt3Nmf350
• absent corpus callosum_Akt3<Nmf350>/Akt3<Nmf350>
  http://metadb.riken.jp/0002196C57BL6JAkt3Nmf350Akt3Nmf350Akt3Nmf350Akt3Nmf350
• increased brain weight_Akt3<Nmf350>/Akt3<Nmf350>
  http://metadb.riken.jp/0002176C57BL6JAkt3Nmf350Akt3Nmf350Akt3Nmf350Akt3Nmf350
• increased brain size_Akt3<Nmf350>/Akt3<Nmf350>
  http://metadb.riken.jp/0005238C57BL6JAkt3Nmf350Akt3Nmf350Akt3Nmf350Akt3Nmf350
• increased susceptibility to pharmacologically induced seizures_Akt3<Nmf350>/Akt3<Nmf350>
  http://metadb.riken.jp/0002906C57BL6JAkt3Nmf350Akt3Nmf350Akt3Nmf350Akt3Nmf350
• maximal tonic hindlimb extension seizures_Fcgr2b<tm1Ttk>/Fcgr2b<tm1Ttk>
  http://metadb.riken.jp/0002194B6129S4Fcgr2btm1TtkFcgr2btm1TtkFcgr2btm1TtkFcgr2btm1Ttk
• tonic-clonic seizures_Akt3<tm1Mbb>/Akt3<tm1Mbb>
  http://metadb.riken.jp/0003997IC57BL6JAkt3tm1MbbAkt3tm1MbbAkt3tm1Mbb
• tonic-clonic seizures_Fcgr2b<tm1Ttk>/Fcgr2b<tm1Ttk>
  http://metadb.riken.jp/0003997B6129S4Fcgr2btm1TtkFcgr2btm1TtkFcgr2btm1TtkFcgr2btm1Ttk

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• tonic-clonic seizures in RBRC02330
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1013467
• abnormal seizure response to electrical stimulation in RBRC02329
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1011593
• tonic-clonic seizures in RBRC02329
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1011613
• maximal tonic hindlimb extension seizures in RBRC02329
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1011604
• tonic-clonic seizures in RBRC06308
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1009767
• maximal tonic hindlimb extension seizures in RBRC02330
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1013457
• maximal tonic hindlimb extension seizures in RBRC06308
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1009758
• abnormal seizure response to electrical stimulation in RBRC02330
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1013445
• abnormal seizure response to electrical stimulation in RBRC06308
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1009747