Nieves. Mijimolle, et.al., Protein farnesyltransferase in embryogenesis, adult homeostasis, and tumor development., Cancer cell, 2005, 7

http://rdf.ncbi.nlm.nih.gov/pubmed/15837621

Nieves. Mijimolle, et.al., Protein farnesyltransferase in embryogenesis, adult homeostasis, and tumor development., Cancer cell, 2005, 7

http://rdf.ncbi.nlm.nih.gov/pubmed/

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD09109
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD09109

allele

http://purl.org/net/cito/citesAsAuthority

• Fntb<tm1Bbd>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3581447
• Fntb<tm1.1Bbd>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3581448

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal hematopoietic system physiology_Fntb<tm1Bbd>/Fntb<tm1Bbd>,Polr2a<tm1(cre/ERT2)Bbd>/Polr2a<tm1(cre/ERT2)Bbd>
  http://metadb.riken.jp/0001545I129S1Sv129X1SvJC57BL6CD1SJLFntbtm1BbdFntbtm1BbdPolr2atm1creERT2BbdPolr2atm1creERT2BbdPolr2atm1creERT2BbdFntbtm1Bbd
• increased lung adenocarcinoma incidence_Fntb<tm1Bbd>/Fntb<tm1Bbd>,Kras<tm1Bbd>/Kras<+>,Polr2a<tm1(cre/ERT2)Bbd>/Polr2a<tm1(cre/ERT2)Bbd>
  http://metadb.riken.jp/0002027I129S1Sv129X1SvJC57BL6CD1SJLFntbtm1BbdFntbtm1BbdKrastm1BbdKrasPolr2atm1creERT2BbdPolr2atm1creERT2BbdKrasFntbtm1BbdPolr2atm1creERT2BbdKrastm1Bbd
• increased lung adenoma incidence_Fntb<tm1Bbd>/Fntb<tm1Bbd>,Kras<tm1Bbd>/Kras<+>,Polr2a<tm1(cre/ERT2)Bbd>/Polr2a<tm1(cre/ERT2)Bbd>
  http://metadb.riken.jp/0002048I129S1Sv129X1SvJC57BL6CD1SJLFntbtm1BbdFntbtm1BbdKrastm1BbdKrasPolr2atm1creERT2BbdPolr2atm1creERT2BbdKrasFntbtm1BbdPolr2atm1creERT2BbdKrastm1Bbd
• abnormal ectoderm development_Fntb<tm1.1Bbd>/Fntb<tm1.1Bbd>
  http://metadb.riken.jp/0001675I129S1Sv129X1SvJCD1Fntbtm11BbdFntbtm11BbdFntbtm11Bbd
• small spleen_Fntb<tm1Bbd>/Fntb<tm1.1Bbd>,Polr2a<tm1(cre/ERT2)Bbd>/Polr2a<tm1(cre/ERT2)Bbd>
  http://metadb.riken.jp/0000692I129S1Sv129X1SvJC57BL6CD1SJLFntbtm1BbdFntbtm11BbdPolr2atm1creERT2BbdPolr2atm1creERT2BbdFntbtm1BbdPolr2atm1creERT2BbdFntbtm11Bbd
• delayed wound healing_Fntb<tm1Bbd>/Fntb<tm1Bbd>,Polr2a<tm1(cre/ERT2)Bbd>/Polr2a<tm1(cre/ERT2)Bbd>
  http://metadb.riken.jp/0002908I129S1Sv129X1SvJC57BL6CD1SJLFntbtm1BbdFntbtm1BbdPolr2atm1creERT2BbdPolr2atm1creERT2BbdPolr2atm1creERT2BbdFntbtm1Bbd
• decreased cell proliferation_Fntb<tm1Bbd>/Fntb<tm1Bbd>,Polr2a<tm1(cre/ERT2)Bbd>/Polr2a<tm1(cre/ERT2)Bbd>
  http://metadb.riken.jp/0000352I129S1Sv129X1SvJC57BL6CD1SJLFntbtm1BbdFntbtm1BbdPolr2atm1creERT2BbdPolr2atm1creERT2BbdPolr2atm1creERT2BbdFntbtm1Bbd
• abnormal hematopoietic system physiology_Fntb<tm1Bbd>/Fntb<tm1.1Bbd>,Polr2a<tm1(cre/ERT2)Bbd>/Polr2a<tm1(cre/ERT2)Bbd>
  http://metadb.riken.jp/0001545I129S1Sv129X1SvJC57BL6CD1SJLFntbtm1BbdFntbtm11BbdPolr2atm1creERT2BbdPolr2atm1creERT2BbdFntbtm1BbdPolr2atm1creERT2BbdFntbtm11Bbd
• delayed wound healing_Fntb<tm1Bbd>/Fntb<tm1.1Bbd>,Polr2a<tm1(cre/ERT2)Bbd>/Polr2a<tm1(cre/ERT2)Bbd>
  http://metadb.riken.jp/0002908I129S1Sv129X1SvJC57BL6CD1SJLFntbtm1BbdFntbtm11BbdPolr2atm1creERT2BbdPolr2atm1creERT2BbdFntbtm1BbdPolr2atm1creERT2BbdFntbtm11Bbd
• decreased incidence of tumors by chemical induction_Fntb<tm1Bbd>/Fntb<tm1Bbd>,Polr2a<tm1(cre/ERT2)Bbd>/Polr2a<tm1(cre/ERT2)Bbd>
  http://metadb.riken.jp/0004502I129S1Sv129X1SvJC57BL6CD1SJLFntbtm1BbdFntbtm1BbdPolr2atm1creERT2BbdPolr2atm1creERT2BbdPolr2atm1creERT2BbdFntbtm1Bbd
• decreased inner cell mass proliferation_Fntb<tm1.1Bbd>/Fntb<tm1.1Bbd>
  http://metadb.riken.jp/0012113I129S1Sv129X1SvJCD1Fntbtm11BbdFntbtm11BbdFntbtm11Bbd
• small spleen_Fntb<tm1Bbd>/Fntb<tm1Bbd>,Polr2a<tm1(cre/ERT2)Bbd>/Polr2a<tm1(cre/ERT2)Bbd>
  http://metadb.riken.jp/0000692I129S1Sv129X1SvJC57BL6CD1SJLFntbtm1BbdFntbtm1BbdPolr2atm1creERT2BbdPolr2atm1creERT2BbdPolr2atm1creERT2BbdFntbtm1Bbd
• decreased cell proliferation_Fntb<tm1Bbd>/Fntb<tm1.1Bbd>,Polr2a<tm1(cre/ERT2)Bbd>/Polr2a<tm1(cre/ERT2)Bbd>
  http://metadb.riken.jp/0000352I129S1Sv129X1SvJC57BL6CD1SJLFntbtm1BbdFntbtm11BbdPolr2atm1creERT2BbdPolr2atm1creERT2BbdFntbtm1BbdPolr2atm1creERT2BbdFntbtm11Bbd
• embryonic lethality during organogenesis, complete penetrance_Fntb<tm1.1Bbd>/Fntb<tm1.1Bbd>
  http://metadb.riken.jp/0011098I129S1Sv129X1SvJCD1Fntbtm11BbdFntbtm11BbdFntbtm11Bbd
• decreased incidence of tumors by chemical induction_Fntb<tm1Bbd>/Fntb<tm1.1Bbd>,Polr2a<tm1(cre/ERT2)Bbd>/Polr2a<tm1(cre/ERT2)Bbd>
  http://metadb.riken.jp/0004502I129S1Sv129X1SvJC57BL6CD1SJLFntbtm1BbdFntbtm11BbdPolr2atm1creERT2BbdPolr2atm1creERT2BbdFntbtm1BbdPolr2atm1creERT2BbdFntbtm11Bbd