Amy E. Kiernan, et.al., The Notch ligands DLL1 and JAG2 act synergistically to regulate hair cell development in the mammalian inner ear., Development (Cambridge, England), 2005, 132

http://rdf.ncbi.nlm.nih.gov/pubmed/16141228

Amy E. Kiernan, et.al., The Notch ligands DLL1 and JAG2 act synergistically to regulate hair cell development in the mammalian inner ear., Development (Cambridge, England), 2005, 132

http://rdf.ncbi.nlm.nih.gov/pubmed/

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD25201
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD25201

allele

http://purl.org/net/cito/citesAsAuthority

• Dll1<tm2Gos>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3776424

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal cochlear hair cell morphology_Dll1<tm1Gos>/Dll1<tm2Gos>,Jag2<tm1Grid>/Jag2<tm1Grid>
  http://metadb.riken.jp/0002622I129S1Sv129S1SvImJ129X1SvJC57BL6JDll1tm1GosDll1tm2GosJag2tm1GridJag2tm1GridJag2tm1GridDll1tm2GosDll1tm1Gos
• increased cochlear inner hair cell number_Jag2<tm1Grid>/Jag2<tm1Grid>
  http://metadb.riken.jp/0004395I129S1Sv129S1SvImJC57BL6JJag2tm1GridJag2tm1GridJag2tm1Grid
• increased cochlear inner hair cell number_Dll1<tm1Gos>/Dll1<+>,Jag2<tm1Grid>/Jag2<tm1Grid>
  http://metadb.riken.jp/0004395I129S1Sv129S1SvImJ129X1SvJC57BL6JDll1tm1GosDll1Jag2tm1GridJag2tm1GridDll1Dll1tm1GosJag2tm1Grid
• decreased organ of Corti supporting cell number_Dll1<tm1Gos>/Dll1<tm2Gos>,Jag2<tm1Grid>/Jag2<tm1Grid>
  http://metadb.riken.jp/0004497I129S1Sv129S1SvImJ129X1SvJC57BL6JDll1tm1GosDll1tm2GosJag2tm1GridJag2tm1GridJag2tm1GridDll1tm2GosDll1tm1Gos
• increased cochlear inner hair cell number_Dll1<tm2Gos>/Dll1<+>,Jag2<tm1Grid>/Jag2<+>
  http://metadb.riken.jp/0004395I129S1Sv129S1SvImJC57BL6JDll1tm2GosDll1Jag2tm1GridJag2Jag2tm1GridDll1tm2GosDll1Jag2
• decreased organ of Corti supporting cell number_Notch1<tm1Grid>/Notch1<tm2Rko>,Foxg1<tm1(cre)Skm>/Foxg1<+>
  http://metadb.riken.jp/0004497I129C57BL6JSwissWebsterNotch1tm1GridNotch1tm2RkoFoxg1tm1creSkmFoxg1Notch1tm1GridNotch1tm2RkoFoxg1tm1creSkmFoxg1
• increased cochlear inner hair cell number_Dll1<tm1Gos>/Dll1<+>,Jag2<tm1Grid>/Jag2<+>
  http://metadb.riken.jp/0004395I129S1Sv129S1SvImJ129X1SvJC57BL6JDll1tm1GosDll1Jag2tm1GridJag2Dll1tm1GosJag2Dll1Jag2tm1Grid
• increased cochlear outer hair cell number_Jag2<tm1Grid>/Jag2<tm1Grid>
  http://metadb.riken.jp/0004401I129S1Sv129S1SvImJC57BL6JJag2tm1GridJag2tm1GridJag2tm1Grid
• increased cochlear inner hair cell number_Notch1<tm1Grid>/Notch1<tm2Rko>,Foxg1<tm1(cre)Skm>/Foxg1<+>
  http://metadb.riken.jp/0004395I129C57BL6JSwissWebsterNotch1tm1GridNotch1tm2RkoFoxg1tm1creSkmFoxg1Notch1tm1GridNotch1tm2RkoFoxg1tm1creSkmFoxg1
• increased cochlear outer hair cell number_Dll1<tm2Gos>/Dll1<+>,Jag2<tm1Grid>/Jag2<+>
  http://metadb.riken.jp/0004401I129S1Sv129S1SvImJC57BL6JDll1tm2GosDll1Jag2tm1GridJag2Jag2tm1GridDll1tm2GosDll1Jag2
• increased cochlear inner hair cell number_Dll1<tm1Gos>/Dll1<tm2Gos>,Jag2<tm1Grid>/Jag2<tm1Grid>
  http://metadb.riken.jp/0004395I129S1Sv129S1SvImJ129X1SvJC57BL6JDll1tm1GosDll1tm2GosJag2tm1GridJag2tm1GridJag2tm1GridDll1tm2GosDll1tm1Gos
• postnatal lethality, complete penetrance_Jag2<tm1Grid>/Jag2<tm1Grid>
  http://metadb.riken.jp/0011085I129S1Sv129S1SvImJC57BL6JJag2tm1GridJag2tm1GridJag2tm1Grid
• abnormal somite development_Dll1<tm1Gos>/Dll1<tm2Gos>
  http://metadb.riken.jp/0001688I129S1Sv129X1SvJC57BL6JDll1tm1GosDll1tm2GosDll1tm2GosDll1tm1Gos
• increased cochlear outer hair cell number_Dll1<tm1Gos>/Dll1<+>,Jag2<tm1Grid>/Jag2<+>
  http://metadb.riken.jp/0004401I129S1Sv129S1SvImJ129X1SvJC57BL6JDll1tm1GosDll1Jag2tm1GridJag2Dll1tm1GosJag2Dll1Jag2tm1Grid
• abnormal orientation of cochlear hair cell stereociliary bundles_Dll1<tm1Gos>/Dll1<tm2Gos>,Jag2<tm1Grid>/Jag2<tm1Grid>
  http://metadb.riken.jp/0004522I129S1Sv129S1SvImJ129X1SvJC57BL6JDll1tm1GosDll1tm2GosJag2tm1GridJag2tm1GridJag2tm1GridDll1tm2GosDll1tm1Gos
• increased cochlear outer hair cell number_Dll1<tm1Gos>/Dll1<tm2Gos>,Jag2<tm1Grid>/Jag2<tm1Grid>
  http://metadb.riken.jp/0004401I129S1Sv129S1SvImJ129X1SvJC57BL6JDll1tm1GosDll1tm2GosJag2tm1GridJag2tm1GridJag2tm1GridDll1tm2GosDll1tm1Gos
• abnormal orientation of cochlear hair cell stereociliary bundles_Jag2<tm1Grid>/Jag2<tm1Grid>
  http://metadb.riken.jp/0004522I129S1Sv129S1SvImJC57BL6JJag2tm1GridJag2tm1GridJag2tm1Grid
• abnormal organ of Corti morphology_Dll1<tm1Gos>/Dll1<+>,Jag2<tm1Grid>/Jag2<tm1Grid>
  http://metadb.riken.jp/0000042I129S1Sv129S1SvImJ129X1SvJC57BL6JDll1tm1GosDll1Jag2tm1GridJag2tm1GridDll1Dll1tm1GosJag2tm1Grid
• abnormal organ of Corti morphology_Dll1<tm1Gos>/Dll1<tm2Gos>,Jag2<tm1Grid>/Jag2<tm1Grid>
  http://metadb.riken.jp/0000042I129S1Sv129S1SvImJ129X1SvJC57BL6JDll1tm1GosDll1tm2GosJag2tm1GridJag2tm1GridJag2tm1GridDll1tm2GosDll1tm1Gos