Amy E. Kiernan, et.al., The Notch ligands DLL1 and JAG2 act synergistically to regulate hair cell development in the mammalian inner ear., Development (Cambridge, England), 2005, 132

http://rdf.ncbi.nlm.nih.gov/pubmed/16141228

Amy E. Kiernan, et.al., The Notch ligands DLL1 and JAG2 act synergistically to regulate hair cell development in the mammalian inner ear., Development (Cambridge, England), 2005, 132

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Dll1<tm2Gos>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3776424

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal cochlear hair cell morphology_Dll1<tm1Gos>/Dll1<tm2Gos>,Jag2<tm1Grid>/Jag2<tm1Grid>
  http://metadb.riken.jp/0002622I129S1Sv129S1SvImJ129X1SvJC57BL6JDll1tm1GosDll1tm2GosJag2tm1GridJag2tm1GridJag2tm1GridDll1tm2GosDll1tm1Gos
• increased cochlear inner hair cell number_Jag2<tm1Grid>/Jag2<tm1Grid>
  http://metadb.riken.jp/0004395I129S1Sv129S1SvImJC57BL6JJag2tm1GridJag2tm1GridJag2tm1Grid
• increased cochlear inner hair cell number_Dll1<tm1Gos>/Dll1<+>,Jag2<tm1Grid>/Jag2<tm1Grid>
  http://metadb.riken.jp/0004395I129S1Sv129S1SvImJ129X1SvJC57BL6JDll1tm1GosDll1Jag2tm1GridJag2tm1GridDll1Dll1tm1GosJag2tm1Grid
• decreased organ of Corti supporting cell number_Dll1<tm1Gos>/Dll1<tm2Gos>,Jag2<tm1Grid>/Jag2<tm1Grid>
  http://metadb.riken.jp/0004497I129S1Sv129S1SvImJ129X1SvJC57BL6JDll1tm1GosDll1tm2GosJag2tm1GridJag2tm1GridJag2tm1GridDll1tm2GosDll1tm1Gos
• increased cochlear inner hair cell number_Dll1<tm2Gos>/Dll1<+>,Jag2<tm1Grid>/Jag2<+>
  http://metadb.riken.jp/0004395I129S1Sv129S1SvImJC57BL6JDll1tm2GosDll1Jag2tm1GridJag2Jag2tm1GridDll1tm2GosDll1Jag2
• decreased organ of Corti supporting cell number_Notch1<tm1Grid>/Notch1<tm2Rko>,Foxg1<tm1(cre)Skm>/Foxg1<+>
  http://metadb.riken.jp/0004497I129C57BL6JSwissWebsterNotch1tm1GridNotch1tm2RkoFoxg1tm1creSkmFoxg1Notch1tm1GridNotch1tm2RkoFoxg1tm1creSkmFoxg1
• increased cochlear inner hair cell number_Dll1<tm1Gos>/Dll1<+>,Jag2<tm1Grid>/Jag2<+>
  http://metadb.riken.jp/0004395I129S1Sv129S1SvImJ129X1SvJC57BL6JDll1tm1GosDll1Jag2tm1GridJag2Dll1tm1GosJag2Dll1Jag2tm1Grid
• increased cochlear outer hair cell number_Jag2<tm1Grid>/Jag2<tm1Grid>
  http://metadb.riken.jp/0004401I129S1Sv129S1SvImJC57BL6JJag2tm1GridJag2tm1GridJag2tm1Grid
• increased cochlear inner hair cell number_Notch1<tm1Grid>/Notch1<tm2Rko>,Foxg1<tm1(cre)Skm>/Foxg1<+>
  http://metadb.riken.jp/0004395I129C57BL6JSwissWebsterNotch1tm1GridNotch1tm2RkoFoxg1tm1creSkmFoxg1Notch1tm1GridNotch1tm2RkoFoxg1tm1creSkmFoxg1
• increased cochlear outer hair cell number_Dll1<tm2Gos>/Dll1<+>,Jag2<tm1Grid>/Jag2<+>
  http://metadb.riken.jp/0004401I129S1Sv129S1SvImJC57BL6JDll1tm2GosDll1Jag2tm1GridJag2Jag2tm1GridDll1tm2GosDll1Jag2
• increased cochlear inner hair cell number_Dll1<tm1Gos>/Dll1<tm2Gos>,Jag2<tm1Grid>/Jag2<tm1Grid>
  http://metadb.riken.jp/0004395I129S1Sv129S1SvImJ129X1SvJC57BL6JDll1tm1GosDll1tm2GosJag2tm1GridJag2tm1GridJag2tm1GridDll1tm2GosDll1tm1Gos
• postnatal lethality, complete penetrance_Jag2<tm1Grid>/Jag2<tm1Grid>
  http://metadb.riken.jp/0011085I129S1Sv129S1SvImJC57BL6JJag2tm1GridJag2tm1GridJag2tm1Grid
• abnormal somite development_Dll1<tm1Gos>/Dll1<tm2Gos>
  http://metadb.riken.jp/0001688I129S1Sv129X1SvJC57BL6JDll1tm1GosDll1tm2GosDll1tm2GosDll1tm1Gos
• increased cochlear outer hair cell number_Dll1<tm1Gos>/Dll1<+>,Jag2<tm1Grid>/Jag2<+>
  http://metadb.riken.jp/0004401I129S1Sv129S1SvImJ129X1SvJC57BL6JDll1tm1GosDll1Jag2tm1GridJag2Dll1tm1GosJag2Dll1Jag2tm1Grid
• abnormal orientation of cochlear hair cell stereociliary bundles_Dll1<tm1Gos>/Dll1<tm2Gos>,Jag2<tm1Grid>/Jag2<tm1Grid>
  http://metadb.riken.jp/0004522I129S1Sv129S1SvImJ129X1SvJC57BL6JDll1tm1GosDll1tm2GosJag2tm1GridJag2tm1GridJag2tm1GridDll1tm2GosDll1tm1Gos
• increased cochlear outer hair cell number_Dll1<tm1Gos>/Dll1<tm2Gos>,Jag2<tm1Grid>/Jag2<tm1Grid>
  http://metadb.riken.jp/0004401I129S1Sv129S1SvImJ129X1SvJC57BL6JDll1tm1GosDll1tm2GosJag2tm1GridJag2tm1GridJag2tm1GridDll1tm2GosDll1tm1Gos
• abnormal orientation of cochlear hair cell stereociliary bundles_Jag2<tm1Grid>/Jag2<tm1Grid>
  http://metadb.riken.jp/0004522I129S1Sv129S1SvImJC57BL6JJag2tm1GridJag2tm1GridJag2tm1Grid
• abnormal organ of Corti morphology_Dll1<tm1Gos>/Dll1<+>,Jag2<tm1Grid>/Jag2<tm1Grid>
  http://metadb.riken.jp/0000042I129S1Sv129S1SvImJ129X1SvJC57BL6JDll1tm1GosDll1Jag2tm1GridJag2tm1GridDll1Dll1tm1GosJag2tm1Grid
• abnormal organ of Corti morphology_Dll1<tm1Gos>/Dll1<tm2Gos>,Jag2<tm1Grid>/Jag2<tm1Grid>
  http://metadb.riken.jp/0000042I129S1Sv129S1SvImJ129X1SvJC57BL6JDll1tm1GosDll1tm2GosJag2tm1GridJag2tm1GridJag2tm1GridDll1tm2GosDll1tm1Gos

class

http://purl.org/net/cito/citesAsAuthority

• Dll1<tm2Gos>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3776424

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD25201
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD25201