T. Iwakuma, et.al., Mtbp haploinsufficiency in mice increases tumor metastasis., Oncogene, 2008, 27

http://rdf.ncbi.nlm.nih.gov/pubmed/17906694

T. Iwakuma, et.al., Mtbp haploinsufficiency in mice increases tumor metastasis., Oncogene, 2008, 27

http://rdf.ncbi.nlm.nih.gov/pubmed/

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD12003
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD12003

allele

http://purl.org/net/cito/citesAsAuthority

• Mtbp<tm1Glo>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3794647

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased tumor incidence_Mtbp<tm1Glo>/Mtbp<+>,Trp53<tm1Tyj>/Trp53<+>
  http://metadb.riken.jp/0002020I129S2SvPas129S7SvEvBrdC57BL6JMtbptm1GloMtbpTrp53tm1TyjTrp53Trp53tm1TyjTrp53Mtbptm1GloMtbp
• embryonic lethality between implantation and somite formation, complete penetrance_Mtbp<tm1Glo>/Mtbp<tm1Glo>,Trp53<tm1Tyj>/Trp53<+>
  http://metadb.riken.jp/0011096I129S2SvPas129S7SvEvBrdC57BL6JMtbptm1GloMtbptm1GloTrp53tm1TyjTrp53Mtbptm1GloTrp53tm1TyjTrp53
• premature death_Mtbp<tm1Glo>/Mtbp<+>,Trp53<tm1Tyj>/Trp53<+>
  http://metadb.riken.jp/0002083I129S2SvPas129S7SvEvBrdC57BL6JMtbptm1GloMtbpTrp53tm1TyjTrp53Trp53tm1TyjTrp53Mtbptm1GloMtbp
• increased metastatic potential_Mtbp<tm1Glo>/Mtbp<+>,Trp53<tm1Tyj>/Trp53<+>
  http://metadb.riken.jp/0001272I129S2SvPas129S7SvEvBrdC57BL6JMtbptm1GloMtbpTrp53tm1TyjTrp53Trp53tm1TyjTrp53Mtbptm1GloMtbp
• increased leukemia incidence_Trp53<tm1Tyj>/Trp53<+>
  http://metadb.riken.jp/0002026I129SvC57BL6Trp53tm1TyjTrp53Trp53Trp53tm1Tyj
• embryonic lethality between implantation and somite formation, complete penetrance_Mtbp<tm1Glo>/Mtbp<tm1Glo>,Trp53<tm1Tyj>/Trp53<tm1Tyj>
  http://metadb.riken.jp/0011096I129S2SvPas129S7SvEvBrdC57BL6JMtbptm1GloMtbptm1GloTrp53tm1TyjTrp53tm1TyjTrp53tm1TyjMtbptm1Glo
• embryonic lethality between implantation and somite formation, complete penetrance_Mtbp<tm1Glo>/Mtbp<tm1Glo>
  http://metadb.riken.jp/0011096I129S7SvEvBrdC57BL6JMtbptm1GloMtbptm1GloMtbptm1Glo
• increased tumor incidence_Trp53<tm1Tyj>/Trp53<+>
  http://metadb.riken.jp/0002020I129SvC57BL6Trp53tm1TyjTrp53Trp53Trp53tm1Tyj
• premature death_Trp53<tm1Tyj>/Trp53<+>
  http://metadb.riken.jp/0002083I129SvC57BL6Trp53tm1TyjTrp53Trp53Trp53tm1Tyj
• increased lymphoma incidence_Trp53<tm1Tyj>/Trp53<+>
  http://metadb.riken.jp/0012431I129SvC57BL6Trp53tm1TyjTrp53Trp53Trp53tm1Tyj
• increased leukemia incidence_Mtbp<tm1Glo>/Mtbp<+>,Trp53<tm1Tyj>/Trp53<+>
  http://metadb.riken.jp/0002026I129S2SvPas129S7SvEvBrdC57BL6JMtbptm1GloMtbpTrp53tm1TyjTrp53Trp53tm1TyjTrp53Mtbptm1GloMtbp
• increased lymphoma incidence_Mtbp<tm1Glo>/Mtbp<+>,Trp53<tm1Tyj>/Trp53<+>
  http://metadb.riken.jp/0012431I129S2SvPas129S7SvEvBrdC57BL6JMtbptm1GloMtbpTrp53tm1TyjTrp53Trp53tm1TyjTrp53Mtbptm1GloMtbp