Etsuko. Ohta, et.al., Analysis of development of lesions in mice with serine palmitoyltransferase (SPT) deficiency -Sptlc2 conditional knockout mice-., Experimental animals, 2009, 58

http://rdf.ncbi.nlm.nih.gov/pubmed/19897935

Etsuko. Ohta, et.al., Analysis of development of lesions in mice with serine palmitoyltransferase (SPT) deficiency -Sptlc2 conditional knockout mice-., Experimental animals, 2009, 58

http://rdf.ncbi.nlm.nih.gov/pubmed/

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD14948
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD14948

allele

http://purl.org/net/cito/citesAsAuthority

• Sptlc2<tm1Yhir>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5523495

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal spleen morphology_Sptlc2<tm1Yhir>/Sptlc2<tm1Yhir>,Gt(ROSA)26Sor<tm9(cre/ESR1)Arte>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0000689IC57BL6C57BL6NTacSptlc2tm1YhirSptlc2tm1YhirGtROSA26Sortm9creESR1ArteGtROSA26SorGtROSA26Sortm9creESR1ArteGtROSA26SorSptlc2tm1Yhir
• abnormal large intestine crypts of Lieberkuhn morphology_Sptlc2<tm1Yhir>/Sptlc2<tm1Yhir>,Gt(ROSA)26Sor<tm9(cre/ESR1)Arte>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0004842IC57BL6C57BL6NTacSptlc2tm1YhirSptlc2tm1YhirGtROSA26Sortm9creESR1ArteGtROSA26SorGtROSA26Sortm9creESR1ArteGtROSA26SorSptlc2tm1Yhir
• decreased lymphocyte cell number_Sptlc2<tm1Yhir>/Sptlc2<tm1Yhir>,Gt(ROSA)26Sor<tm9(cre/ESR1)Arte>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0005016IC57BL6C57BL6NTacSptlc2tm1YhirSptlc2tm1YhirGtROSA26Sortm9creESR1ArteGtROSA26SorGtROSA26Sortm9creESR1ArteGtROSA26SorSptlc2tm1Yhir
• abnormal small intestine crypts of Lieberkuhn morphology_Sptlc2<tm1Yhir>/Sptlc2<tm1Yhir>,Gt(ROSA)26Sor<tm9(cre/ESR1)Arte>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0004841IC57BL6C57BL6NTacSptlc2tm1YhirSptlc2tm1YhirGtROSA26Sortm9creESR1ArteGtROSA26SorGtROSA26Sortm9creESR1ArteGtROSA26SorSptlc2tm1Yhir
• reticulocytopenia_Sptlc2<tm1Yhir>/Sptlc2<tm1Yhir>,Gt(ROSA)26Sor<tm9(cre/ESR1)Arte>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0008941IC57BL6C57BL6NTacSptlc2tm1YhirSptlc2tm1YhirGtROSA26Sortm9creESR1ArteGtROSA26SorGtROSA26Sortm9creESR1ArteGtROSA26SorSptlc2tm1Yhir
• increased blood urea nitrogen level_Sptlc2<tm1Yhir>/Sptlc2<tm1Yhir>,Gt(ROSA)26Sor<tm9(cre/ESR1)Arte>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0005565IC57BL6C57BL6NTacSptlc2tm1YhirSptlc2tm1YhirGtROSA26Sortm9creESR1ArteGtROSA26SorGtROSA26Sortm9creESR1ArteGtROSA26SorSptlc2tm1Yhir
• abnormal small intestinal villus morphology_Sptlc2<tm1Yhir>/Sptlc2<tm1Yhir>,Gt(ROSA)26Sor<tm9(cre/ESR1)Arte>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0008108IC57BL6C57BL6NTacSptlc2tm1YhirSptlc2tm1YhirGtROSA26Sortm9creESR1ArteGtROSA26SorGtROSA26Sortm9creESR1ArteGtROSA26SorSptlc2tm1Yhir
• increased hemoglobin content_Sptlc2<tm1Yhir>/Sptlc2<tm1Yhir>,Gt(ROSA)26Sor<tm9(cre/ESR1)Arte>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0005564IC57BL6C57BL6NTacSptlc2tm1YhirSptlc2tm1YhirGtROSA26Sortm9creESR1ArteGtROSA26SorGtROSA26Sortm9creESR1ArteGtROSA26SorSptlc2tm1Yhir
• abnormal circulating protein level_Sptlc2<tm1Yhir>/Sptlc2<tm1Yhir>,Gt(ROSA)26Sor<tm9(cre/ESR1)Arte>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0005416IC57BL6C57BL6NTacSptlc2tm1YhirSptlc2tm1YhirGtROSA26Sortm9creESR1ArteGtROSA26SorGtROSA26Sortm9creESR1ArteGtROSA26SorSptlc2tm1Yhir
• cellular necrosis_Sptlc2<tm1Yhir>/Sptlc2<tm1Yhir>,Gt(ROSA)26Sor<tm9(cre/ESR1)Arte>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0000316IC57BL6C57BL6NTacSptlc2tm1YhirSptlc2tm1YhirGtROSA26Sortm9creESR1ArteGtROSA26SorGtROSA26Sortm9creESR1ArteGtROSA26SorSptlc2tm1Yhir
• decreased spleen weight_Sptlc2<tm1Yhir>/Sptlc2<tm1Yhir>,Gt(ROSA)26Sor<tm9(cre/ESR1)Arte>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0004953IC57BL6C57BL6NTacSptlc2tm1YhirSptlc2tm1YhirGtROSA26Sortm9creESR1ArteGtROSA26SorGtROSA26Sortm9creESR1ArteGtROSA26SorSptlc2tm1Yhir
• abnormal pancreatic acinar cell zymogen granule morphology_Sptlc2<tm1Yhir>/Sptlc2<tm1Yhir>,Gt(ROSA)26Sor<tm9(cre/ESR1)Arte>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0009160IC57BL6C57BL6NTacSptlc2tm1YhirSptlc2tm1YhirGtROSA26Sortm9creESR1ArteGtROSA26SorGtROSA26Sortm9creESR1ArteGtROSA26SorSptlc2tm1Yhir
• increased neutrophil cell number_Sptlc2<tm1Yhir>/Sptlc2<tm1Yhir>,Gt(ROSA)26Sor<tm9(cre/ESR1)Arte>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0000219IC57BL6C57BL6NTacSptlc2tm1YhirSptlc2tm1YhirGtROSA26Sortm9creESR1ArteGtROSA26SorGtROSA26Sortm9creESR1ArteGtROSA26SorSptlc2tm1Yhir
• increased hematocrit_Sptlc2<tm1Yhir>/Sptlc2<tm1Yhir>,Gt(ROSA)26Sor<tm9(cre/ESR1)Arte>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0002608IC57BL6C57BL6NTacSptlc2tm1YhirSptlc2tm1YhirGtROSA26Sortm9creESR1ArteGtROSA26SorGtROSA26Sortm9creESR1ArteGtROSA26SorSptlc2tm1Yhir
• increased erythrocyte cell number_Sptlc2<tm1Yhir>/Sptlc2<tm1Yhir>,Gt(ROSA)26Sor<tm9(cre/ESR1)Arte>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0003131IC57BL6C57BL6NTacSptlc2tm1YhirSptlc2tm1YhirGtROSA26Sortm9creESR1ArteGtROSA26SorGtROSA26Sortm9creESR1ArteGtROSA26SorSptlc2tm1Yhir
• increased circulating alanine transaminase level_Sptlc2<tm1Yhir>/Sptlc2<tm1Yhir>,Gt(ROSA)26Sor<tm9(cre/ESR1)Arte>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0002941IC57BL6C57BL6NTacSptlc2tm1YhirSptlc2tm1YhirGtROSA26Sortm9creESR1ArteGtROSA26SorGtROSA26Sortm9creESR1ArteGtROSA26SorSptlc2tm1Yhir
• abnormal thymus morphology_Sptlc2<tm1Yhir>/Sptlc2<tm1Yhir>,Gt(ROSA)26Sor<tm9(cre/ESR1)Arte>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0000703IC57BL6C57BL6NTacSptlc2tm1YhirSptlc2tm1YhirGtROSA26Sortm9creESR1ArteGtROSA26SorGtROSA26Sortm9creESR1ArteGtROSA26SorSptlc2tm1Yhir
• abnormal intestinal mucosa morphology_Sptlc2<tm1Yhir>/Sptlc2<tm1Yhir>,Gt(ROSA)26Sor<tm9(cre/ESR1)Arte>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0000511IC57BL6C57BL6NTacSptlc2tm1YhirSptlc2tm1YhirGtROSA26Sortm9creESR1ArteGtROSA26SorGtROSA26Sortm9creESR1ArteGtROSA26SorSptlc2tm1Yhir
• increased circulating serum albumin level_Sptlc2<tm1Yhir>/Sptlc2<tm1Yhir>,Gt(ROSA)26Sor<tm9(cre/ESR1)Arte>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0002965IC57BL6C57BL6NTacSptlc2tm1YhirSptlc2tm1YhirGtROSA26Sortm9creESR1ArteGtROSA26SorGtROSA26Sortm9creESR1ArteGtROSA26SorSptlc2tm1Yhir
• abnormal stomach mucosa morphology_Sptlc2<tm1Yhir>/Sptlc2<tm1Yhir>,Gt(ROSA)26Sor<tm9(cre/ESR1)Arte>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0010792IC57BL6C57BL6NTacSptlc2tm1YhirSptlc2tm1YhirGtROSA26Sortm9creESR1ArteGtROSA26SorGtROSA26Sortm9creESR1ArteGtROSA26SorSptlc2tm1Yhir
• decreased thymus weight_Sptlc2<tm1Yhir>/Sptlc2<tm1Yhir>,Gt(ROSA)26Sor<tm9(cre/ESR1)Arte>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0004956IC57BL6C57BL6NTacSptlc2tm1YhirSptlc2tm1YhirGtROSA26Sortm9creESR1ArteGtROSA26SorGtROSA26Sortm9creESR1ArteGtROSA26SorSptlc2tm1Yhir
• sebaceous gland atrophy_Sptlc2<tm1Yhir>/Sptlc2<tm1Yhir>,Gt(ROSA)26Sor<tm9(cre/ESR1)Arte>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0000649IC57BL6C57BL6NTacSptlc2tm1YhirSptlc2tm1YhirGtROSA26Sortm9creESR1ArteGtROSA26SorGtROSA26Sortm9creESR1ArteGtROSA26SorSptlc2tm1Yhir
• increased adrenal gland weight_Sptlc2<tm1Yhir>/Sptlc2<tm1Yhir>,Gt(ROSA)26Sor<tm9(cre/ESR1)Arte>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0013307IC57BL6C57BL6NTacSptlc2tm1YhirSptlc2tm1YhirGtROSA26Sortm9creESR1ArteGtROSA26SorGtROSA26Sortm9creESR1ArteGtROSA26SorSptlc2tm1Yhir
• decreased bone marrow cell number_Sptlc2<tm1Yhir>/Sptlc2<tm1Yhir>,Gt(ROSA)26Sor<tm9(cre/ESR1)Arte>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0000333IC57BL6C57BL6NTacSptlc2tm1YhirSptlc2tm1YhirGtROSA26Sortm9creESR1ArteGtROSA26SorGtROSA26Sortm9creESR1ArteGtROSA26SorSptlc2tm1Yhir

article

http://www.w3.org/2000/01/rdf-schema#seeAlso

• [Blank]

BRC マウスの系統

http://purl.org/net/cito/citesAsAuthority

• B6;129(FVB)-Sptlc2<tm1.1Yhir>
  http://metadb.riken.jp/db/rikenbrc_mouse/RBRC09802

article

http://www.w3.org/2000/01/rdf-schema#seeAlso

• [Blank]