Arjan. van der Flier, et.al., Endothelial alpha5 and alphav integrins cooperate in remodeling of the vasculature during development., Development (Cambridge, England), 2010, 137

http://rdf.ncbi.nlm.nih.gov/pubmed/20570943

Arjan. van der Flier, et.al., Endothelial alpha5 and alphav integrins cooperate in remodeling of the vasculature during development., Development (Cambridge, England), 2010, 137

http://rdf.ncbi.nlm.nih.gov/pubmed/

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD08229
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD08229

allele

http://purl.org/net/cito/citesAsAuthority

• Itga5<tm2.1Hyn>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4818933
• Itga5<tm2Hyn>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4818931

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• ventricular septal defect_Gt(ROSA)26Sor<tm1Sho>/0,Itga5<tm2Hyn>/Itga5<tm1Hyn>,Itgav<tm1Hyn>/Itgav<tm2Hyn>,Tg(Tek-cre)1Ywa/0
  http://metadb.riken.jp/0010402I129C57BL6SJLGtROSA26Sortm1Sho0Itga5tm2HynItga5tm1HynItgavtm1HynItgavtm2HynTgTekcre1Ywa0TgTekcre1YwaGtROSA26Sortm1ShoItga5tm1HynItgavtm2HynItga5tm2HynItgavtm1Hyn
• abnormal ascending aorta morphology_Gt(ROSA)26Sor<tm1Sho>/0,Itga5<tm2Hyn>/Itga5<tm1Hyn>,Itgav<tm1Hyn>/Itgav<tm2Hyn>,Tg(Tek-cre)1Ywa/0
  http://metadb.riken.jp/0009867I129C57BL6SJLGtROSA26Sortm1Sho0Itga5tm2HynItga5tm1HynItgavtm1HynItgavtm2HynTgTekcre1Ywa0TgTekcre1YwaGtROSA26Sortm1ShoItga5tm1HynItgavtm2HynItga5tm2HynItgavtm1Hyn
• patent ductus arteriosus_Gt(ROSA)26Sor<tm1Sho>/0,Itga5<tm2Hyn>/Itga5<tm1Hyn>,Itgav<tm1Hyn>/Itgav<tm2Hyn>,Tg(Tek-cre)1Ywa/0
  http://metadb.riken.jp/0003139I129C57BL6SJLGtROSA26Sortm1Sho0Itga5tm2HynItga5tm1HynItgavtm1HynItgavtm2HynTgTekcre1Ywa0TgTekcre1YwaGtROSA26Sortm1ShoItga5tm1HynItgavtm2HynItga5tm2HynItgavtm1Hyn
• abnormal blood vessel morphology_Itga5<tm2.1Hyn>/Itga5<tm2.1Hyn>
  http://metadb.riken.jp/0001614I129S1Sv129X1SvJC57BL6SJLItga5tm21HynItga5tm21HynItga5tm21Hyn
• postnatal lethality, incomplete penetrance_Itga5<tm2Hyn>/Itga5<tm2Hyn>,Tg(Tek-cre)1Ywa/0
  http://metadb.riken.jp/0011086B6CgItga5tm2HynTgTekcre1YwaItga5tm2HynItga5tm2HynTgTekcre1Ywa0Itga5tm2HynTgTekcre1Ywa
• patent ductus arteriosus_Itga5<tm2Hyn>/Itga5<tm2Hyn>,Tg(Tek-cre)1Ywa/0
  http://metadb.riken.jp/0003139B6CgItga5tm2HynTgTekcre1YwaItga5tm2HynItga5tm2HynTgTekcre1Ywa0Itga5tm2HynTgTekcre1Ywa
• postnatal lethality, incomplete penetrance_Gt(ROSA)26Sor<tm1Sho>/0,Itga5<tm2Hyn>/Itga5<tm1Hyn>,Itgav<tm2Hyn>/Itgav<+>,Tg(Tek-cre)1Ywa/0
  http://metadb.riken.jp/0011086I129C57BL6SJLGtROSA26Sortm1Sho0Itga5tm2HynItga5tm1HynItgavtm2HynItgavTgTekcre1Ywa0Itga5tm1HynTgTekcre1YwaGtROSA26Sortm1ShoItga5tm2HynItgavItgavtm2Hyn
• incomplete somite formation_Itga5<tm2.1Hyn>/Itga5<tm2.1Hyn>
  http://metadb.riken.jp/0001689I129S1Sv129X1SvJC57BL6SJLItga5tm21HynItga5tm21HynItga5tm21Hyn
• abnormal cell adhesion_Itga5<tm1Hyn>/Itga5<tm2Hyn>,Tg(H2-K1-tsA58)11Kio/0,Tg(Tek-cre)1Ywa/0
  http://metadb.riken.jp/0003566I129C57BL6C57BL10CBACaSJLItga5tm1HynItga5tm2HynTgH2K1tsA5811Kio0TgTekcre1Ywa0TgTekcre1YwaItga5tm1HynTgH2K1tsA5811KioItga5tm2Hyn
• lethality throughout fetal growth and development, complete penetrance_Gt(ROSA)26Sor<tm1Sho>/0,Itga5<tm2Hyn>/Itga5<tm1Hyn>,Itgav<tm1Hyn>/Itgav<tm2Hyn>,Tg(Tek-cre)1Ywa/0
  http://metadb.riken.jp/0011099I129C57BL6SJLGtROSA26Sortm1Sho0Itga5tm2HynItga5tm1HynItgavtm1HynItgavtm2HynTgTekcre1Ywa0TgTekcre1YwaGtROSA26Sortm1ShoItga5tm1HynItgavtm2HynItga5tm2HynItgavtm1Hyn
• ventricular septal defect_Gt(ROSA)26Sor<tm1Sho>/0,Itga5<tm2Hyn>/Itga5<tm1Hyn>,Itgav<tm2Hyn>/Itgav<+>,Tg(Tek-cre)1Ywa/0
  http://metadb.riken.jp/0010402I129C57BL6SJLGtROSA26Sortm1Sho0Itga5tm2HynItga5tm1HynItgavtm2HynItgavTgTekcre1Ywa0Itga5tm1HynTgTekcre1YwaGtROSA26Sortm1ShoItga5tm2HynItgavItgavtm2Hyn
• abnormal cell adhesion_Itga5<tm2Hyn>/Itga5<tm2Hyn>,Itgav<tm2Hyn>/Itgav<tm2Hyn>,Tg(H2-K1-tsA58)11Kio/0
  http://metadb.riken.jp/0003566I129C57BL6SJLItga5tm2HynItga5tm2HynItgavtm2HynItgavtm2HynTgH2K1tsA5811Kio0TgH2K1tsA5811KioItgavtm2HynItga5tm2Hyn
• embryonic growth retardation_Itga5<tm2.1Hyn>/Itga5<tm2.1Hyn>
  http://metadb.riken.jp/0003984I129S1Sv129X1SvJC57BL6SJLItga5tm21HynItga5tm21HynItga5tm21Hyn
• no abnormal phenotype detected_Itga5<tm1Hyn>/Itga5<tm2Hyn>,Tg(Tek-cre)1Ywa/0
  http://metadb.riken.jp/0002169I129C57BL6SJLItga5tm1HynItga5tm2HynTgTekcre1Ywa0TgTekcre1YwaItga5tm1HynItga5tm2Hyn
• vascular ring_Gt(ROSA)26Sor<tm1Sho>/0,Itga5<tm2Hyn>/Itga5<tm1Hyn>,Itgav<tm1Hyn>/Itgav<tm2Hyn>,Tg(Tek-cre)1Ywa/0
  http://metadb.riken.jp/0010466I129C57BL6SJLGtROSA26Sortm1Sho0Itga5tm2HynItga5tm1HynItgavtm1HynItgavtm2HynTgTekcre1Ywa0TgTekcre1YwaGtROSA26Sortm1ShoItga5tm1HynItgavtm2HynItga5tm2HynItgavtm1Hyn
• retroesophageal right subclavian artery_Gt(ROSA)26Sor<tm1Sho>/0,Itga5<tm2Hyn>/Itga5<tm1Hyn>,Itgav<tm1Hyn>/Itgav<tm2Hyn>,Tg(Tek-cre)1Ywa/0
  http://metadb.riken.jp/0004160I129C57BL6SJLGtROSA26Sortm1Sho0Itga5tm2HynItga5tm1HynItgavtm1HynItgavtm2HynTgTekcre1Ywa0TgTekcre1YwaGtROSA26Sortm1ShoItga5tm1HynItgavtm2HynItga5tm2HynItgavtm1Hyn
• patent ductus arteriosus_Gt(ROSA)26Sor<tm1Sho>/0,Itga5<tm2Hyn>/Itga5<tm1Hyn>,Itgav<tm2Hyn>/Itgav<+>,Tg(Tek-cre)1Ywa/0
  http://metadb.riken.jp/0003139I129C57BL6SJLGtROSA26Sortm1Sho0Itga5tm2HynItga5tm1HynItgavtm2HynItgavTgTekcre1Ywa0Itga5tm1HynTgTekcre1YwaGtROSA26Sortm1ShoItga5tm2HynItgavItgavtm2Hyn
• embryonic lethality during organogenesis, complete penetrance_Itga5<tm2.1Hyn>/Itga5<tm2.1Hyn>
  http://metadb.riken.jp/0011098I129S1Sv129X1SvJC57BL6SJLItga5tm21HynItga5tm21HynItga5tm21Hyn