C Catharina. Müller, et.al., PEX13 deficiency in mouse brain as a model of Zellweger syndrome: abnormal cerebellum formation, reactive gliosis and oxidative stress., Disease models & mechanisms, 2011, 4

http://rdf.ncbi.nlm.nih.gov/pubmed/20959636

C Catharina. Müller, et.al., PEX13 deficiency in mouse brain as a model of Zellweger syndrome: abnormal cerebellum formation, reactive gliosis and oxidative stress., Disease models & mechanisms, 2011, 4

http://rdf.ncbi.nlm.nih.gov/pubmed/

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD19528
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD19528

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased plasmalogen level_Pex13<tm1Crne>/Pex13<tm1.1Crne>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0012217I129T2SvEmsC57BL6C57BL6JSJLPex13tm1CrnePex13tm11CrneTgNescre1Kln0TgNescre1KlnPex13tm1CrnePex13tm11Crne
• decreased brain plasmalogen level_Pex13<tm1Crne>/Pex13<tm1.1Crne>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0012218I129T2SvEmsC57BL6C57BL6JSJLPex13tm1CrnePex13tm11CrneTgNescre1Kln0TgNescre1KlnPex13tm1CrnePex13tm11Crne
• abnormal Purkinje cell morphology_Pex13<tm1Crne>/Pex13<tm1.1Crne>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0000877I129T2SvEmsC57BL6C57BL6JSJLPex13tm1CrnePex13tm11CrneTgNescre1Kln0TgNescre1KlnPex13tm1CrnePex13tm11Crne
• abnormal cerebellum external granule cell layer morphology_Pex13<tm1Crne>/Pex13<tm1.1Crne>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0000872I129T2SvEmsC57BL6C57BL6JSJLPex13tm1CrnePex13tm11CrneTgNescre1Kln0TgNescre1KlnPex13tm1CrnePex13tm11Crne
• abnormal enzyme/coenzyme activity_Pex13<tm1Crne>/Pex13<tm1.1Crne>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0005584I129T2SvEmsC57BL6C57BL6JSJLPex13tm1CrnePex13tm11CrneTgNescre1Kln0TgNescre1KlnPex13tm1CrnePex13tm11Crne
• weight loss_Pex13<tm1Crne>/Pex13<tm1.1Crne>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0001263I129T2SvEmsC57BL6C57BL6JSJLPex13tm1CrnePex13tm11CrneTgNescre1Kln0TgNescre1KlnPex13tm1CrnePex13tm11Crne
• abnormal cerebellum fissure morphology_Pex13<tm1Crne>/Pex13<tm1.1Crne>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0009267I129T2SvEmsC57BL6C57BL6JSJLPex13tm1CrnePex13tm11CrneTgNescre1Kln0TgNescre1KlnPex13tm1CrnePex13tm11Crne
• decreased body weight_Pex13<tm1Crne>/Pex13<tm1.1Crne>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0001262I129T2SvEmsC57BL6C57BL6JSJLPex13tm1CrnePex13tm11CrneTgNescre1Kln0TgNescre1KlnPex13tm1CrnePex13tm11Crne
• premature death_Pex13<tm1Crne>/Pex13<tm1.1Crne>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0002083I129T2SvEmsC57BL6C57BL6JSJLPex13tm1CrnePex13tm11CrneTgNescre1Kln0TgNescre1KlnPex13tm1CrnePex13tm11Crne
• astrocytosis_Pex13<tm1Crne>/Pex13<tm1.1Crne>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0003354I129T2SvEmsC57BL6C57BL6JSJLPex13tm1CrnePex13tm11CrneTgNescre1Kln0TgNescre1KlnPex13tm1CrnePex13tm11Crne
• abnormal cerebellum development_Pex13<tm1Crne>/Pex13<tm1.1Crne>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0000854I129T2SvEmsC57BL6C57BL6JSJLPex13tm1CrnePex13tm11CrneTgNescre1Kln0TgNescre1KlnPex13tm1CrnePex13tm11Crne
• abnormal Purkinje cell dendrite morphology_Pex13<tm1Crne>/Pex13<tm1.1Crne>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0008572I129T2SvEmsC57BL6C57BL6JSJLPex13tm1CrnePex13tm11CrneTgNescre1Kln0TgNescre1KlnPex13tm1CrnePex13tm11Crne
• impaired coordination_Pex13<tm1Crne>/Pex13<tm1.1Crne>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0001405I129T2SvEmsC57BL6C57BL6JSJLPex13tm1CrnePex13tm11CrneTgNescre1Kln0TgNescre1KlnPex13tm1CrnePex13tm11Crne
• abnormal mitochondrial physiology_Pex13<tm1.1Crne>/Pex13<tm1.1Crne>
  http://metadb.riken.jp/0006036I129T2SvEmsC57BL6JPex13tm11CrnePex13tm11CrnePex13tm11Crne
• thin cerebellar molecular layer_Pex13<tm1Crne>/Pex13<tm1.1Crne>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0000890I129T2SvEmsC57BL6C57BL6JSJLPex13tm1CrnePex13tm11CrneTgNescre1Kln0TgNescre1KlnPex13tm1CrnePex13tm11Crne
• abnormal fatty acid level_Pex13<tm1Crne>/Pex13<tm1.1Crne>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0005280I129T2SvEmsC57BL6C57BL6JSJLPex13tm1CrnePex13tm11CrneTgNescre1Kln0TgNescre1KlnPex13tm1CrnePex13tm11Crne
• limb grasping_Pex13<tm1Crne>/Pex13<tm1.1Crne>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0001513I129T2SvEmsC57BL6C57BL6JSJLPex13tm1CrnePex13tm11CrneTgNescre1Kln0TgNescre1KlnPex13tm1CrnePex13tm11Crne
• gliosis_Pex13<tm1Crne>/Pex13<tm1.1Crne>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0002183I129T2SvEmsC57BL6C57BL6JSJLPex13tm1CrnePex13tm11CrneTgNescre1Kln0TgNescre1KlnPex13tm1CrnePex13tm11Crne
• abnormal reflex_Pex13<tm1Crne>/Pex13<tm1.1Crne>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0001961I129T2SvEmsC57BL6C57BL6JSJLPex13tm1CrnePex13tm11CrneTgNescre1Kln0TgNescre1KlnPex13tm1CrnePex13tm11Crne
• reduced cerebellar foliation_Pex13<tm1Crne>/Pex13<tm1.1Crne>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0009719I129T2SvEmsC57BL6C57BL6JSJLPex13tm1CrnePex13tm11CrneTgNescre1Kln0TgNescre1KlnPex13tm1CrnePex13tm11Crne
• abnormal cerebellar Purkinje cell layer_Pex13<tm1Crne>/Pex13<tm1.1Crne>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0000875I129T2SvEmsC57BL6C57BL6JSJLPex13tm1CrnePex13tm11CrneTgNescre1Kln0TgNescre1KlnPex13tm1CrnePex13tm11Crne
• abnormal cerebellar granule cell migration_Pex13<tm1Crne>/Pex13<tm1.1Crne>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0009977I129T2SvEmsC57BL6C57BL6JSJLPex13tm1CrnePex13tm11CrneTgNescre1Kln0TgNescre1KlnPex13tm1CrnePex13tm11Crne
• abnormal Purkinje cell differentiation_Pex13<tm1Crne>/Pex13<tm1.1Crne>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0008579I129T2SvEmsC57BL6C57BL6JSJLPex13tm1CrnePex13tm11CrneTgNescre1Kln0TgNescre1KlnPex13tm1CrnePex13tm11Crne
• kyphosis_Pex13<tm1Crne>/Pex13<tm1.1Crne>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0000160I129T2SvEmsC57BL6C57BL6JSJLPex13tm1CrnePex13tm11CrneTgNescre1Kln0TgNescre1KlnPex13tm1CrnePex13tm11Crne
• postnatal growth retardation_Pex13<tm1Crne>/Pex13<tm1.1Crne>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0001732I129T2SvEmsC57BL6C57BL6JSJLPex13tm1CrnePex13tm11CrneTgNescre1Kln0TgNescre1KlnPex13tm1CrnePex13tm11Crne
• oxidative stress_Pex13<tm1.1Crne>/Pex13<tm1.1Crne>
  http://metadb.riken.jp/0003674I129T2SvEmsC57BL6JPex13tm11CrnePex13tm11CrnePex13tm11Crne