decreased bone mineral density_Lrp5<tm1Grw>/Lrp5<tm1Grw>

http://metadb.riken.jp/0000063I129S1Sv129X1SvJLrp5tm1GrwLrp5tm1GrwLrp5tm1Grw

decreased bone mineral density_Lrp5<tm1Grw>/Lrp5<tm1Grw>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• low density lipoprotein receptor-related protein 5
  http://metadb.riken.jp/db/mgi_rdf/MGI:1278315

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Lrp5<tm1Grw>/Lrp5<tm1Grw>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Lrp5<tm1Grw>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased bone mineral density
  http://purl.obolibrary.org/obo/MP_0000063

文献

http://purl.org/net/cito/citesAsAuthority

• Philippe. Clément-Lacroix, et.al., Lrp5-independent activation of Wnt signaling by lithium chloride increases bone formation and bone mass in mice., Proceedings of the National Academy of Sciences of the United States of America, 2005, 102
  http://rdf.ncbi.nlm.nih.gov/pubmed/16293698
• Rajendra. Kedlaya, et.al., Sclerostin inhibition reverses skeletal fragility in an Lrp5-deficient mouse model of OPPG syndrome., Science translational medicine, 2013, 5
  http://rdf.ncbi.nlm.nih.gov/pubmed/24225945