decreased bone mineral density_Ghr<tm1.1Masp>/Ghr<tm1.1Masp>,Tg(Alb-cre)21Mgn/0

http://metadb.riken.jp/0000063I129S4SvJaeSorC57BL6DBAGhrtm11MaspGhrtm11MaspTgAlbcre21Mgn0TgAlbcre21MgnGhrtm11Masp

decreased bone mineral density_Ghr<tm1.1Masp>/Ghr<tm1.1Masp>,Tg(Alb-cre)21Mgn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• growth hormone receptor
  http://metadb.riken.jp/db/mgi_rdf/MGI:95708
• transgene insertion 21, Mark A Magnuson
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176226

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ghr<tm1.1Masp>/Ghr<tm1.1Masp>,Tg(Alb-cre)21Mgn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Alb-cre)21Mgn|Ghr<tm1.1Masp>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJaeSor * C57BL/6 * DBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased bone mineral density
  http://purl.obolibrary.org/obo/MP_0000063

文献

http://purl.org/net/cito/citesAsAuthority

• Yong. Fan, et.al., Liver-specific deletion of the growth hormone receptor reveals essential role of growth hormone signaling in hepatic lipid metabolism., The Journal of biological chemistry, 2009, 284
  http://rdf.ncbi.nlm.nih.gov/pubmed/19460757