Yong. Fan, et.al., Liver-specific deletion of the growth hormone receptor reveals essential role of growth hormone signaling in hepatic lipid metabolism., The Journal of biological chemistry, 2009, 284

http://rdf.ncbi.nlm.nih.gov/pubmed/19460757

Yong. Fan, et.al., Liver-specific deletion of the growth hormone receptor reveals essential role of growth hormone signaling in hepatic lipid metabolism., The Journal of biological chemistry, 2009, 284

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Ghr<tm1.1Masp>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4359891
• Ghr<tm1.2Masp>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4359895

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• impaired glucose tolerance_Ghr<tm1.1Masp>/Ghr<tm1.1Masp>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0005293I129S4SvJaeSorC57BL6DBAGhrtm11MaspGhrtm11MaspTgAlbcre21Mgn0TgAlbcre21MgnGhrtm11Masp
• decreased kidney weight_Ghr<tm1.1Masp>/Ghr<tm1.1Masp>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0003918I129S4SvJaeSorC57BL6DBAGhrtm11MaspGhrtm11MaspTgAlbcre21Mgn0TgAlbcre21MgnGhrtm11Masp
• postnatal growth retardation_Ghr<tm1.2Masp>/Ghr<tm1.2Masp>
  http://metadb.riken.jp/0001732I129S4SvJaeSorGhrtm12MaspGhrtm12MaspGhrtm12Masp
• increased circulating growth hormone level_Ghr<tm1.1Masp>/Ghr<tm1.1Masp>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0005123I129S4SvJaeSorC57BL6DBAGhrtm11MaspGhrtm11MaspTgAlbcre21Mgn0TgAlbcre21MgnGhrtm11Masp
• decreased body size_Ghr<tm1.2Masp>/Ghr<tm1.2Masp>
  http://metadb.riken.jp/0001265I129S4SvJaeSorGhrtm12MaspGhrtm12MaspGhrtm12Masp
• decreased circulating insulin-like growth factor I level_Ghr<tm1.1Masp>/Ghr<tm1.1Masp>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0004701I129S4SvJaeSorC57BL6DBAGhrtm11MaspGhrtm11MaspTgAlbcre21Mgn0TgAlbcre21MgnGhrtm11Masp
• increased circulating free fatty acid level_Ghr<tm1.1Masp>/Ghr<tm1.1Masp>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0001554I129S4SvJaeSorC57BL6DBAGhrtm11MaspGhrtm11MaspTgAlbcre21Mgn0TgAlbcre21MgnGhrtm11Masp
• decreased liver triglyceride level_Ghr<tm1.1Masp>/Ghr<tm1.1Masp>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0009356I129S4SvJaeSorC57BL6DBAGhrtm11MaspGhrtm11MaspTgAlbcre21Mgn0TgAlbcre21MgnGhrtm11Masp
• decreased circulating triglyceride level_Ghr<tm1.1Masp>/Ghr<tm1.1Masp>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0002644I129S4SvJaeSorC57BL6DBAGhrtm11MaspGhrtm11MaspTgAlbcre21Mgn0TgAlbcre21MgnGhrtm11Masp
• decreased bone mineral density_Ghr<tm1.1Masp>/Ghr<tm1.1Masp>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0000063I129S4SvJaeSorC57BL6DBAGhrtm11MaspGhrtm11MaspTgAlbcre21Mgn0TgAlbcre21MgnGhrtm11Masp
• increased circulating insulin level_Ghr<tm1.1Masp>/Ghr<tm1.1Masp>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0002079I129S4SvJaeSorC57BL6DBAGhrtm11MaspGhrtm11MaspTgAlbcre21Mgn0TgAlbcre21MgnGhrtm11Masp
• increased liver weight_Ghr<tm1.1Masp>/Ghr<tm1.1Masp>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0002981I129S4SvJaeSorC57BL6DBAGhrtm11MaspGhrtm11MaspTgAlbcre21Mgn0TgAlbcre21MgnGhrtm11Masp
• hepatic steatosis_Ghr<tm1.1Masp>/Ghr<tm1.1Masp>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0002628I129S4SvJaeSorC57BL6DBAGhrtm11MaspGhrtm11MaspTgAlbcre21Mgn0TgAlbcre21MgnGhrtm11Masp

class

http://purl.org/net/cito/citesAsAuthority

• Ghr<tm1.1Masp>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4359891
• Ghr<tm1.2Masp>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4359895