osteoporosis_Brca1<tm2.1Cxd>/Brca1<tm2.1Cxd>,Trp53<tm1Brd>/Trp53<+>

http://metadb.riken.jp/0000066I129S6SvEvTac129S7SvEvBrdBlackSwissFVBBrca1tm21CxdBrca1tm21CxdTrp53tm1BrdTrp53Trp53tm1BrdBrca1tm21CxdTrp53

osteoporosis_Brca1<tm2.1Cxd>/Brca1<tm2.1Cxd>,Trp53<tm1Brd>/Trp53<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• breast cancer 1, early onset
  http://metadb.riken.jp/db/mgi_rdf/MGI:104537
• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Brca1<tm2.1Cxd>/Brca1<tm2.1Cxd>,Trp53<tm1Brd>/Trp53<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Trp53<tm1Brd>|Brca1<tm2.1Cxd>|Trp53<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * 129S7/SvEvBrd * Black Swiss * FVB

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• osteoporosis
  http://purl.obolibrary.org/obo/MP_0000066

文献

http://purl.org/net/cito/citesAsAuthority

• Liu. Cao, et.al., Senescence, aging, and malignant transformation mediated by p53 in mice lacking the Brca1 full-length isoform., Genes & development, 2003, 17
  http://rdf.ncbi.nlm.nih.gov/pubmed/12533509