increased monocyte cell number_Tet2<tm1.1Iaai>/Tet2<tm1.1Iaai>,Tg(Vav1-cre)1Graf/0

http://metadb.riken.jp/0000220I129SSvEvC57BL6Tet2tm11IaaiTet2tm11IaaiTgVav1cre1Graf0Tet2tm11IaaiTgVav1cre1Graf

increased monocyte cell number_Tet2<tm1.1Iaai>/Tet2<tm1.1Iaai>,Tg(Vav1-cre)1Graf/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• tet methylcytosine dioxygenase 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:2443298
• transgene insertion 1, Thomas Graf
  http://metadb.riken.jp/db/mgi_rdf/MGI:3765352

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tet2<tm1.1Iaai>/Tet2<tm1.1Iaai>,Tg(Vav1-cre)1Graf/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tet2<tm1.1Iaai>|Tg(Vav1-cre)1Graf

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S/SvEv * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased monocyte cell number
  http://purl.obolibrary.org/obo/MP_0000220

文献

http://purl.org/net/cito/citesAsAuthority

• Kelly. Moran-Crusio, et.al., Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation., Cancer cell, 2011, 20
  http://rdf.ncbi.nlm.nih.gov/pubmed/21723200