increased monocyte cell number_Ins2<Akita>/Ins2<+>,Prf1<tm1Sdz>/Prf1<tm1Sdz>,Rag1<tm1Mom>/Rag1<tm1Mom>

http://metadb.riken.jp/0000220NODCgRag1tm1MomIns2AkitaPrf1tm1SdzIns2AkitaIns2Prf1tm1SdzPrf1tm1SdzRag1tm1MomRag1tm1MomPrf1tm1SdzIns2Rag1tm1MomIns2Akita

increased monocyte cell number_Ins2<Akita>/Ins2<+>,Prf1<tm1Sdz>/Prf1<tm1Sdz>,Rag1<tm1Mom>/Rag1<tm1Mom>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• recombination activating gene 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:97848
• perforin 1 (pore forming protein)
  http://metadb.riken.jp/db/mgi_rdf/MGI:97551
• insulin II
  http://metadb.riken.jp/db/mgi_rdf/MGI:96573

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ins2<Akita>/Ins2<+>,Prf1<tm1Sdz>/Prf1<tm1Sdz>,Rag1<tm1Mom>/Rag1<tm1Mom>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Prf1<tm1Sdz>|Ins2<+>|Rag1<tm1Mom>|Ins2<Akita>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• NOD.Cg-Rag1<tm1Mom> Ins2<Akita> Prf1<tm1Sdz>

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased monocyte cell number
  http://purl.obolibrary.org/obo/MP_0000220

文献

http://purl.org/net/cito/citesAsAuthority

• T. Pearson, et.al., A new immunodeficient hyperglycaemic mouse model based on the Ins2Akita mutation for analyses of human islet and beta stem and progenitor cell function., Diabetologia, 2008, 51
  http://rdf.ncbi.nlm.nih.gov/pubmed/18563383