decreased neutrophil cell number_Cul4a/Pcid2<tm2Ktc>/Cul4a/Pcid2<tm2Ktc>,Tg(Mx1-cre)1Cgn/0

http://metadb.riken.jp/0000222I129SSvEvC57BL6CBAFVBNCul4aPcid2tm2KtcCul4aPcid2tm2KtcTgMx1cre1Cgn0Cul4aPcid2tm2KtcTgMx1cre1Cgn

decreased neutrophil cell number_Cul4a/Pcid2<tm2Ktc>/Cul4a/Pcid2<tm2Ktc>,Tg(Mx1-cre)1Cgn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• PCI domain containing 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:2443003
• cullin 4A
  http://metadb.riken.jp/db/mgi_rdf/MGI:1914487
• transgene insertion 1, University of Cologne
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176072

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cul4a/Pcid2<tm2Ktc>/Cul4a/Pcid2<tm2Ktc>,Tg(Mx1-cre)1Cgn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Cul4a/Pcid2<tm2Ktc>|Tg(Mx1-cre)1Cgn

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S/SvEv * C57BL/6 * CBA * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased neutrophil cell number
  http://purl.obolibrary.org/obo/MP_0000222

文献

http://purl.org/net/cito/citesAsAuthority

• David L. Waning, et.al., Cul4A is required for hematopoietic cell viability and its deficiency leads to apoptosis., Blood, 2008, 112
  http://rdf.ncbi.nlm.nih.gov/pubmed/18339895