David L. Waning, et.al., Cul4A is required for hematopoietic cell viability and its deficiency leads to apoptosis., Blood, 2008, 112

http://rdf.ncbi.nlm.nih.gov/pubmed/18339895

David L. Waning, et.al., Cul4A is required for hematopoietic cell viability and its deficiency leads to apoptosis., Blood, 2008, 112

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Cul4a/Pcid2<tm2Ktc>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3851113
• Cul4a/Pcid2<tm2Ktc>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3805522

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased bone marrow cell number_Cul4a/Pcid2<tm2Ktc>/Cul4a/Pcid2<tm2Ktc>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0000333I129SSvEvC57BL6CBAFVBNCul4aPcid2tm2KtcCul4aPcid2tm2KtcTgMx1cre1Cgn0Cul4aPcid2tm2KtcTgMx1cre1Cgn
• thrombocytopenia_Cul4a/Pcid2<tm2Ktc>/Cul4a/Pcid2<tm2Ktc>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0003179I129SSvEvC57BL6CBAFVBNCul4aPcid2tm2KtcCul4aPcid2tm2KtcTgMx1cre1Cgn0Cul4aPcid2tm2KtcTgMx1cre1Cgn
• abnormal spleen morphology_Cul4a/Pcid2<tm2Ktc>/Cul4a/Pcid2<tm2Ktc>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0000689I129SSvEvC57BL6CBAFVBNCul4aPcid2tm2KtcCul4aPcid2tm2KtcTgMx1cre1Cgn0Cul4aPcid2tm2KtcTgMx1cre1Cgn
• decreased neutrophil cell number_Cul4a/Pcid2<tm2Ktc>/Cul4a/Pcid2<tm2Ktc>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0000222I129SSvEvC57BL6CBAFVBNCul4aPcid2tm2KtcCul4aPcid2tm2KtcTgMx1cre1Cgn0Cul4aPcid2tm2KtcTgMx1cre1Cgn
• impaired hematopoiesis_Cul4a/Pcid2<tm2Ktc>/Cul4a/Pcid2<tm2Ktc>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0001606I129SSvEvC57BL6CBAFVBNCul4aPcid2tm2KtcCul4aPcid2tm2KtcTgMx1cre1Cgn0Cul4aPcid2tm2KtcTgMx1cre1Cgn
• abnormal spleen capsule morphology_Cul4a/Pcid2<tm2Ktc>/Cul4a/Pcid2<tm2Ktc>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0002227I129SSvEvC57BL6CBAFVBNCul4aPcid2tm2KtcCul4aPcid2tm2KtcTgMx1cre1Cgn0Cul4aPcid2tm2KtcTgMx1cre1Cgn
• decreased spleen white pulp amount_Cul4a/Pcid2<tm2Ktc>/Cul4a/Pcid2<tm2Ktc>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0008479I129SSvEvC57BL6CBAFVBNCul4aPcid2tm2KtcCul4aPcid2tm2KtcTgMx1cre1Cgn0Cul4aPcid2tm2KtcTgMx1cre1Cgn
• decreased hematocrit_Cul4a/Pcid2<tm2Ktc>/Cul4a/Pcid2<tm2Ktc>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0000208I129SSvEvC57BL6CBAFVBNCul4aPcid2tm2KtcCul4aPcid2tm2KtcTgMx1cre1Cgn0Cul4aPcid2tm2KtcTgMx1cre1Cgn
• decreased monocyte cell number_Cul4a/Pcid2<tm2Ktc>/Cul4a/Pcid2<tm2Ktc>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0000223I129SSvEvC57BL6CBAFVBNCul4aPcid2tm2KtcCul4aPcid2tm2KtcTgMx1cre1Cgn0Cul4aPcid2tm2KtcTgMx1cre1Cgn
• abnormal enterocyte morphology_Cul4a/Pcid2<tm2Ktc>/Cul4a/Pcid2<tm2Ktc>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0000479I129SSvEvC57BL6CBAFVBNCul4aPcid2tm2KtcCul4aPcid2tm2KtcTgMx1cre1Cgn0Cul4aPcid2tm2KtcTgMx1cre1Cgn
• spleen hypoplasia_Cul4a/Pcid2<tm2Ktc>/Cul4a/Pcid2<tm2Ktc>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0000694I129SSvEvC57BL6CBAFVBNCul4aPcid2tm2KtcCul4aPcid2tm2KtcTgMx1cre1Cgn0Cul4aPcid2tm2KtcTgMx1cre1Cgn
• decreased spleen red pulp amount_Cul4a/Pcid2<tm2Ktc>/Cul4a/Pcid2<tm2Ktc>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0008477I129SSvEvC57BL6CBAFVBNCul4aPcid2tm2KtcCul4aPcid2tm2KtcTgMx1cre1Cgn0Cul4aPcid2tm2KtcTgMx1cre1Cgn
• abnormal definitive hematopoiesis_Cul4a/Pcid2<tm2Ktc>/Cul4a/Pcid2<tm2Ktc>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0002123I129SSvEvC57BL6CBAFVBNCul4aPcid2tm2KtcCul4aPcid2tm2KtcTgMx1cre1Cgn0Cul4aPcid2tm2KtcTgMx1cre1Cgn
• increased enterocyte apoptosis_Cul4a/Pcid2<tm2Ktc>/Cul4a/Pcid2<tm2Ktc>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0008885I129SSvEvC57BL6CBAFVBNCul4aPcid2tm2KtcCul4aPcid2tm2KtcTgMx1cre1Cgn0Cul4aPcid2tm2KtcTgMx1cre1Cgn
• small thymus_Cul4a/Pcid2<tm2Ktc>/Cul4a/Pcid2<tm2Ktc>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0000706I129SSvEvC57BL6CBAFVBNCul4aPcid2tm2KtcCul4aPcid2tm2KtcTgMx1cre1Cgn0Cul4aPcid2tm2KtcTgMx1cre1Cgn
• decreased lymphocyte cell number_Cul4a/Pcid2<tm2Ktc>/Cul4a/Pcid2<tm2Ktc>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0005016I129SSvEvC57BL6CBAFVBNCul4aPcid2tm2KtcCul4aPcid2tm2KtcTgMx1cre1Cgn0Cul4aPcid2tm2KtcTgMx1cre1Cgn
• decreased hematopoietic stem cell number_Cul4a/Pcid2<tm2Ktc>/Cul4a/Pcid2<tm2Ktc>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0004810I129SSvEvC57BL6CBAFVBNCul4aPcid2tm2KtcCul4aPcid2tm2KtcTgMx1cre1Cgn0Cul4aPcid2tm2KtcTgMx1cre1Cgn
• decreased spleen weight_Cul4a/Pcid2<tm2Ktc>/Cul4a/Pcid2<tm2Ktc>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0004953I129SSvEvC57BL6CBAFVBNCul4aPcid2tm2KtcCul4aPcid2tm2KtcTgMx1cre1Cgn0Cul4aPcid2tm2KtcTgMx1cre1Cgn
• abnormal leukocyte morphology_Cul4a/Pcid2<tm2Ktc>/Cul4a/Pcid2<tm2Ktc>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0008246I129SSvEvC57BL6CBAFVBNCul4aPcid2tm2KtcCul4aPcid2tm2KtcTgMx1cre1Cgn0Cul4aPcid2tm2KtcTgMx1cre1Cgn
• premature death_Cul4a/Pcid2<tm2Ktc>/Cul4a/Pcid2<tm2Ktc>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0002083I129SSvEvC57BL6CBAFVBNCul4aPcid2tm2KtcCul4aPcid2tm2KtcTgMx1cre1Cgn0Cul4aPcid2tm2KtcTgMx1cre1Cgn
• small intestinal villus atrophy_Cul4a/Pcid2<tm2Ktc>/Cul4a/Pcid2<tm2Ktc>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0014078I129SSvEvC57BL6CBAFVBNCul4aPcid2tm2KtcCul4aPcid2tm2KtcTgMx1cre1Cgn0Cul4aPcid2tm2KtcTgMx1cre1Cgn
• abnormal small intestine crypts of Lieberkuhn morphology_Cul4a/Pcid2<tm2Ktc>/Cul4a/Pcid2<tm2Ktc>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0004841I129SSvEvC57BL6CBAFVBNCul4aPcid2tm2KtcCul4aPcid2tm2KtcTgMx1cre1Cgn0Cul4aPcid2tm2KtcTgMx1cre1Cgn

class

http://purl.org/net/cito/citesAsAuthority

• Cul4a/Pcid2<tm2Ktc>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3851113
• Cul4a/Pcid2<tm2Ktc>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3805522

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD28693
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD28693
• CD13117
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD13117